Suppositories in anal disorders: A review

European Review for Medical and Pharmacological Sciences

Volumn 11, Issue 3, 2007, Pages 165-170

  Gupta, Pravin J ^a  

^a Gupta Nursing Home   (India)

Author keywords

Anal; Ano rectal disorder; Proctology; Rectum; Suppositories

Indexed keywords

ALLANTOIN; ALOE VERA EXTRACT; ALUMINUM CHLORIDE; ANTIINFECTIVE AGENT; ASTRINGENT AGENT; BENZALKONIUM CHLORIDE; BENZOCAINE; BORIC ACID; CALAMINE; CENTBUCRIDINE; CINCHOCAINE; DOBESILATE CALCIUM; DYCLONINE; FRAMYCETIN; HAMAMELIS EXTRACT; HYDROCORTISONE; KERATOLYTIC AGENT; LIDOCAINE; LOCAL ANESTHETIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; PHENYLEPHRINE; POLICRESULEN; PRAMOCAINE; PREDNISOLONE; RESORCINOL; STEROID; TETRACAINE; UNINDEXED DRUG; VASOCONSTRICTOR AGENT; ZINC OXIDE;

AGRANULOCYTOSIS; ANALGESIC ACTIVITY; ANORECTAL DISEASE; ANTIINFLAMMATORY ACTIVITY; ANUS DISEASE; ANUS FISSURE; ANUS PRURITUS; BURNING SENSATION; DRUG ABSORPTION; DRUG CONTRAINDICATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG HYPERSENSITIVITY; DRUG INDICATION; DRUG INDUCED HEADACHE; DRUG MECHANISM; EVIDENCE BASED MEDICINE; FLUSHING; HEMORRHOID; HUMAN; MEDICAL LITERATURE; MEDLINE; MUCOSAL DISEASE; NONHUMAN; OUTCOME ASSESSMENT; PATIENT CARE; PROCTITIS; PRURITUS; RECTUM DISEASE; RECTUM ULCER; REVIEW; SIDE EFFECT; SKIN DEFECT; SKIN IRRITATION; SUPPOSITORY; TACHYCARDIA; UNSPECIFIED SIDE EFFECT;

ANUS DISEASES; DRUG DELIVERY SYSTEMS; HUMANS; SUPPOSITORIES;

EID: 34547494036     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (34)

1. NEIGER A. Pathogenesis, clinical aspects and conservative therapy of hemorrhoids. Schweiz Med Wochenschr 1980; 110: 1387-1390.
2. SIMON I. Use of the suppositories (anal cones) in medical practice; considerations and proposals. Athena 1956; 22: 253-258.
3. POLLINZI V, SORTINI A, RIGOBELLO P, SALA P. Clinical study of a new preparation in the treatment of anorectal varices. Minerva Chir 1977; 32: 27-34.
4. LIEBERMAN W. The place of suppositories and ointments in proctologic practice (a re-appraisal and new data). Am J Proctol 1966; 17: 371-376.
5. ZAKHARASH MP, POIDA OI. Application of preparations relief ultra and relief advance in practice of coloproctological department. Klin Khir 2005; 10: 9-12.
6. NEIGER A, HERMS E. The symptomatic therapy of hemorrhoids and anal eczema-a report of experiences from proctology practice. Schweiz Rundsch Med Prax 1990; 79: 918-920.
7. POPRZEN V, POPOVIC R. Spectrodensitometric determination of lidocaine-chloride in antihemorrhoidal agents. Vojnosanit Pregl 1989; 46:191-194.
8. SMITH RB, MOODIE J. Comparative efficacy and tolerability of two ointment and suppositories preparations ("Uniroid" and "Proctosedyl") in the treatment of second degree haemorrhoids in general practice. Curr Med Res Opin 1988; 11: 34-40.
9. NISHIKI K, KUDOH D, NISHINAGA K, IWAI K, NAKAGAWA H. Neriproct: its anti-inflammatory effect on an experimentally induced hemorrhoid model in the rat. Nippon Yakurigaku Zasshi 1988; 92: 227-240.
10. SUBRAMANYAM K, PATTERSON M, GOURLEY WK. Effects of preparation-H on wound healing in the rectum of man. Dig Dis Sci 1984; 29: 829-832.
11. SCHLUMPF R, BUCHMANN P. A new concept in the suppositories therapy of proctological diseases-aluminum hydroxychloride foam suppositories. Schweiz Rundsch Med Prax 1988; 77: 1066-1068.
12. MARSICANO LJ, PEREZ M, URQUIOLA G. Effectiveness and innocuousness of the association of calcium dobesilate, dexamethasone acetate and lidocaine versus prednisolone capronate with dibucaine clorohydrate in the treatment of hemorrhoids. G E N 1995; 49: 296-302.
13. ESPINOSA DJ. Analytical review of multicenter studies with policresulene for hemorrhoidal pathologies. Acta Gastroenterol Latinoam 2000; 30: 177-186.
14. KASPARI M, GUTZMER R, KASPARI T, KAPP A, BRODERSEN JP. Application of imiquimod by suppositories (anal tampons) efficiently prevents recurrences after ablation of anal canal condyloma. Br J Dermatol 2002; 147: 757-759.
15. HO YH, SEOW-CHOEN F, LOW JY, TAN M, LEONG AP. Randomized controlled trial of trimebutine (anal sphincter relaxant) for pain after haemorrhoidectomy. Br J Surg 1997; 84: 377-379.
16. KANAMOTO I, NAKAGAWA T, HORIKOSHI I, KOIZUMI T, TAZAWA K, FUJIMAKI M. Pharmacokinetics of two rectal dosage forms of ketoprofen in patients after anal surgery. J Pharmacobiodyn 1988; 11: 141-145.
17. CAVINA E, PAGLIAI EF. Hemorrhoids; a new method of symptomatic treatment. Sedative cryotherapy using the Criosuppost self-applicator. Minerva Med 1983; 74: 447-452.
18. FAURE H. Promethazine suppositories in the treatment of certain hemorrhoidal complications; trichloracetic acid in the treatment of anal fissures. Maroc Med 1954; 33: 1112-1113.
19. YANG XD, WANG JP, KANG JB, CHEN ZW, CAO JD, YAO LQ, YANG XQ. Comparison of the efficacy and safety of compound carraghenates cream and compound carraghenates suppositories in the treatment of mixed hemorrhoids. Zhonghua Wei Chang Wai Ke Za Zhi 2005; 8: 220-222.
20. REJMAN F. Use of Roinal suppositories in patients with anorectal complaints. Duodecim 1962; 78: 727-729.
21. MOGGIAN G. Controlled clinical trial of anti-hemorrhoidal glycofuranoside derivative for local use. Minerva Med 1973; 64: 215-218.
22. MIYASHITA F, NISHITANI R. Treatment of hemorrhoid with Indacin suppositories-including experiences in administration after anal operation. Nippon Daicho Komonbyo Gakkai Zasshi 1970; 23: 22-26.
23. KNOCH HG. Use of Prothanon suppositories in the treatment of hemorrhoids. Pharmazie 1970; 25: 113-115.
24. MILSTEIN J. Clinical Experiments on suppositories with a base of Anthraquinone Glycosides from Rhubarb (sodium derivates) and from Aloe (silver derivatives) in hemorrhoidal disease. Clinique (Paris) 1963; 58: 677-682.
25. MILSTEIN MJ. Therapeutic trial of phenylindanedione ("pindione") in suppositories form in hemorrhoids. Concours Med 1960; 82:1509-1512.
26. REZNIK BN, DUL'TSEV IUV, NIKITIN AM, KAPULLER LL, KOPLATADZE AM. Treatment of internal hemorrhoids by the method of nonsurgical ligature combined with proctoglivenol. Vestn Khir Im I I Grek 1976; 117: 46-49.
27. ABD-EL-MAEBOUD KH, EL-NAGGAR T, EL-HAWI EM, MAHMOUD SA, ABD-EL-HAY S. Rectal suppositories: Commonsense and mode of insertion. Lancet 1991; 338: 798-800.
28. D'HAENS G, BREYSEM Y, RUTGEERTS P, VAN BESIEN B, GEBOES K, PONETTE E, VANTRAPPEN G.. Proctitis and rectal stenosis induced by nonsteroidal anti-inflammatory suppositories. J Clin Gastroenterol 1993; 17: 207-212.
29. GIZZI G, VILLANI V, BRANDI G, PAGANELLI GM, DI FEBO G, BIASCO G. Ano-rectal lesions in patients taking suppositories containing non-steroidal anti-inflammatory drugs (NSAID). Endoscopy 1990; 22: 146-148.
30. LANTHIER P, DETRY R, DEBONGNIE JC, MAHIEU P, VANHEUVERZWYN R. Solitary lesions of the rectum caused by suppositories combining acetylsalicylic acid and paracetamol. Gastroenterol Clin Biol 1987; 11: 250-253.
31. CHAMBRE JF, PERARNAU JM, ULRICH J, ARBOGAST J. Peri-rectal infectious cellulitis with septicemia of anal origin. Suppositories on trial. Therapie 1991; 46: 383-385.
32. ALLAIN H, RAMELET AA, POLARD E, BENTUE-FERRER D. Safety of calcium dobesilate in chronic venous disease, diabetic retinopathy and haemorrhoids. Drug Saf 2004; 27: 649-660.
33. ARNOLD K, AUEL H, Multicenter clinical study of a novel steroid-free preparation in proctology. Arzneimittelforschung 1976; 26: 96-99.
34. MENTES BB, GORGUL A, TATLICIOGLU E, AYOGLU F, UNAL S. Efficacy of calcium dobesilate in treating acute attacks of hemorrhoidal disease. Dis Colon Rectum 2001; 44: 1489-1495.