Preparation and evaluation of nanoparticles made of chitosan or N-trimethyl chitosan and a cisplatin-alginate complex

Journal of Controlled Release

Volumn 121, Issue 1-2, 2007, Pages 110-123

  Cafaggi, S ^a   Russo, E ^a   Stefani, R ^a   Leardi, R ^a   Caviglioli, G ^a   Parodi, B ^a   Bignardi, G ^a   De Totero, D ^b   Aiello, C ^b   Viale, M ^b  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

Alginate; Cisplatin; Cytotoxic activity; Nanoparticles; Quaternized chitosan

Indexed keywords

ANIONIC CISPLATIN-ALGINATE COMPLEXES; N-TRIMETHYL CHITOSAN; POSITIVE NANOPARTICLES;

CHITIN; COMPLEXATION; COULOMB INTERACTIONS; SUBSTITUTION REACTIONS; SURFACE CHARGE; ZETA POTENTIAL;

NANOPARTICLES;

ALGINIC ACID; BUFFER; CARBOXYLIC ACID DERIVATIVE; CHITOSAN; CISPLATIN; N TRIMETHYLCHITOSAN; NANOPARTICLE; POLYELECTROLYTE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL LINE; COMPLEX FORMATION; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; CYTOTOXICITY; ELECTRICITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; NANOTECHNOLOGY; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; STATISTICAL ANALYSIS; SURFACE PROPERTY; ZETA POTENTIAL;

ALGINATES; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BUFFERS; CELL LINE, TUMOR; CHITOSAN; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROSTATICS; FEMALE; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; HYDROGEN-ION CONCENTRATION; LEUKEMIA; LUNG NEOPLASMS; MICE; NANOPARTICLES; OVARIAN NEOPLASMS; PARTICLE SIZE;

EID: 34547469938     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2007.05.037     Document Type: Article

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