Amorphous silicon sensors for single and multicolor detection of biomolecules

IEEE Sensors Journal

Volumn 7, Issue 9, 2007, Pages 1274-1279

  Caputo, D ^a   De Cesare, G ^a   Nascetti, A ^a   Negri, Rodolfo ^a   Scipinotti, R ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Amorphous silicon; DNA detection; Fluorochromes; Multicolor; Photosensor

Indexed keywords

AMORPHOUS SILICON; BIOMOLECULES; DNA; LUMINESCENCE; OPTIMIZATION; RADIATION EFFECTS; SIGNAL TO NOISE RATIO;

FLUOROCHROMES; MEASUREMENT EQUIPMENTS; MULTICOLOR DETECTION; PHOTOSENSORS;

CHEMICAL SENSORS;

EID: 34547452617     PISSN: 1530437X     EISSN: None     Source Type: Journal    
DOI: 10.1109/JSEN.2007.901257     Document Type: Article

References (22)

1. F. H. Kasten, "Introduction to fluorescent probes; Properties, history and applications," in Fluorescent and Luminescent Probes for Biological Activity, W. T. Mason, Ed. New York: Academic, 1993, pp. 12-33.
2. B. Valeur, Molecular Fluorescence: Principles and Applications. New York: Wiley, 2002.
3. D. L. Taylor, A. S. Waggoner, R. F. Murphy, F. Lanni, and R. Birge, Applications of Fluorescence in the Biomedical Sciences. New York: A. R. Liss, 1986.
4. W. F. Patton, "A thousand points of light: The application of fluorescence detection technologies to two-dimensional gel electrophoresis and proteomics," Electrophoresis, vol. 21, no. 6, pp. 1123-1144, 2000.
5. M. Gore, Spectrophotometry and Spectrofluorimetry: A Practical Approach, 2nd ed. Oxford, U.K.: Oxford Univ. Press, 2000.
6. I. A. Hemmila, Applications of Fluorescence in Immunoassays. New York: Wiley, 1991.
7. V. Allan, Protein Localization by Fluorescence Microscopy: A Practical Approach. Oxford, U.K.: Oxford Univ. Press, 1999.
8. M. Schena, DNA Microarray Biochip Technology. Natick, MA: BioTechniques Press, 2000.
9. D. Botwell and J. Sambrook, DNA Microarrays (A molecular Cloning Manual). New York: Cold Spring Harbor Lab. Press, 2003.
10. R. M Ostroff, D. Hopkins, A. B. Haeberli, W. Baouchi, and B. Polisky, "Thin film biosensor for rapid visual detection, of nucleic acid targets," Clin. Chem., vol. 45, pp. 1659-1164, 1999.
11. J. B. Lamture, K. L. Beattie, B. E. Burke, M. D. Eggers, D. J. Ehrlich, R. Fowler, M. A. Hollis, B. B. Kosicki, R. K. Reich, and S. R. Smith, "Direct detection of nucleic acid hybridization on the surface of a charge coupled device," Nucleic Acids Res., vol. 22, no. 1.1, pp. 2121-2125, 1994.
12. D. Caputo, G. de Cesare, A. Nascetti, and R. Negri, "Spectral tuned amoiphous silicon p-i-n for DNA detection," J. Non-Cryst. Sol., vol. 352, pp. 2004-2007, 2006.
13. F. Fixe, V. Chu, D. M. F. Prazeres, and J. P. Conde, "An on-chip thin film photodetector for the quantification of DNA probes and targets in microarrays," Nucleic Acids Res., vol. 32, no. 9, pp. e70-e75, 2004.
14. T. Kamei, B. M. Paegel, J. R. Scherer, A. M. Skelley, R. A. Street, and R. A. Mathies, "Integrated hydrogenated amorphous Si photodiode detector for microfluidic bioanalytical devices," Anal. Chem., vol. 75, pp. 5300-5305, 2003.
15. G. de Cesare, D. Caputo, A. Nascetti, C. Guiducci, and B. Riccò, "Hydrogenated amorphous silicon ultraviolet sensor for deoxyribonucleic acid analysis," Appl. Phys. Lett., vol. 88, p. 083904, 2006.
16. Fluorescence Imaging Principles and Methods Amersham Biosciences, 63-0035-28, 2002.
17. R. A. Street, Hydrogenated Amorphous Silicon. Cambridge, U.K.: Cambridge Univ. Press, 1991.
18. D. Caputo, U. Forghieri, and F. Palma, "Low-temperature admittance measurement in thin film amorphous silicon structures," J. Appl. Phys., vol. 82, no. 2, pp. 733-741, 1997.
19. D. Caputo, "Degradation and annealing of amorphous silicon solar cells by current injection-Experiment and modeling," Sol. En. Mat. and Sol. Cells, vol. 59, no. 3, pp. 289-298, 1999.
20. G. de Cesare, F. Irrera, F. Lemmi, and F. Palma, "Tunable photodetectors based on amorphous Si/SiC heterostructures," IEEE Trans. Electron Devices, vol. 42, no. 5, pp. 835-840, May 1995.
21. H. Yu, J. Chao, D. Patek, R. Mujumdar, S. Mujumdar, and A. S. Waggoner, "Cyanine dye dUTP analogs for enzymatic labeling of DNA probes," Nucleic Acids Res., vol. 22, no. 15, pp. 3226-3232, 1994.
22. "Lite and Express Microarrays Scanners: Scan Array Express," Perkin Elmer-Packard, Tech. Manual, User Manual Part No. 80M-826 Rev. B 2002.