The Renin-Angiotensin System in Malignant Hypertension Revisited: Plasma Renin Activity, Microangiopathic Hemolysis, and Renal Failure in Malignant Hypertension

American Journal of Hypertension

Volumn 20, Issue 8, 2007, Pages 900-906

  van den Born, Bert Jan H ^a   Koopmans, Richard P ^a   van Montfrans, Gert A ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

hemolysis; malignant hypertension; renal insufficiency; Renin angiotensin system

Indexed keywords

ALDOSTERONE; ANGIOTENSIN I; CREATININE; LACTATE DEHYDROGENASE; POTASSIUM; RENIN;

ADULT; ARTICLE; BLOOD VESSEL INJURY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; ENZYME ACTIVITY; FEMALE; HEMOLYSIS; HUMAN; INTRAVASCULAR HEMOLYSIS; KIDNEY FAILURE; KIDNEY FUNCTION; MALE; MALIGNANT HYPERTENSION; MICROANGIOPATHIC HEMOLYSIS; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM;

ADULT; ALDOSTERONE; BIOLOGICAL MARKERS; CREATININE; FEMALE; FOLLOW-UP STUDIES; HEMOLYSIS; HUMANS; HYPERTENSION, MALIGNANT; KIDNEY FAILURE; MALE; MIDDLE AGED; PROGNOSIS; PROSPECTIVE STUDIES; RENIN; RENIN-ANGIOTENSIN SYSTEM; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

EID: 34547418087     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjhyper.2007.02.018     Document Type: Article

References (28)

1. Laragh J.H., Angers M., Kelly W.G., and Lieberman S. Hypotensive agents and pressor substances. The effect of epinephrine, norepinephrine, angiotensin II, and others on the secretory rate of aldosterone in man. JAMA 174 (1960) 234-240
2. Buhler F.R., Laragh J.H., Vaughan Jr. E.D., Brunner H.R., Gavras H., and Baer L. Antihypertensive action of propranolol. Specific antirenin responses in high and normal renin forms of essential, renal, renovascular and malignant hypertension. Am J Cardiol 32 (1973) 511-522
3. Linton A.L., Gavras H., Gleadle R.I., Hutchison H.E., Lawson D.H., Lever A.F., MacAdam R.F., McNicol G.P., and Robertson J.I. Microangiopathic haemolytic anaemia and the pathogenesis of malignant hypertension. Lancet 1 (1969) 1277-1282
4. Laragh J.H., Ulick S., Januszewicz V., Deming Q.B., Kelly W.G., and Lieberman S. Aldosterone secretion and primary and malignant hypertension. J Clin Invest 39 (1960) 1091-1106
5. Brown J.J., Davies D.L., Lever A.F., and Robertson J.I. Plasma renin concentration in human hypertension. II. Renin in relation to aetiology. Br Med J 5472 (1965) 1215-1219
6. Creditor M.C., and Loschky U.K. Plasma renin activity in hypertension. Am J Med 43 (1967) 371-382
7. Kincaid-Smith P. Malignant hypertension: mechanisms and management. Pharmacol Ther 9 (1980) 245-269
8. Wilson C., and Byrom F.B. Renal changes in malignant hypertension. Lancet I (1939) 136-139
9. Kincaid-Smith P. Malignant hypertension. J Hypertens 9 (1991) 893-899
10. Ganten D., Wagner J., Zeh K., Bader M., Michel J.B., Paul M., Zimmermann F., Ruf P., Hilgenfeldt U., and Ganten U. Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes. Proc Natl Acad Sci USA 89 (1992) 7806-7810
11. Mervaala E., Muller D.N., Schmidt F., Park J.K., Gross V., Bader M., Breu V., Ganten D., Haller H., and Luft F.C. Blood pressure-independent effects in rats with human renin and angiotensinogen genes. Hypertension 35 (2000) 587-594
12. Montgomery H.E., Kiernan L.A., Whitworth C.E., Fleming S., Unger T., Gohlke P., Mullins J.J., and McEwan J.R. Inhibition of tissue angiotensin converting enzyme activity prevents malignant hypertension in TGR(mREN2)27. J Hypertens 16 (1998) 635-643
13. van den Born B.J., Honnebier U.P., Koopmans R.P., and van Montfrans G.A. Microangiopathic hemolysis and renal failure in malignant hypertension. Hypertension 45 (2005) 246-251
14. Hollemans H.J., van der Meer J., and Kloosterziel W. Measurement of renin activity in plasma by a radioimmunoassay for angiotensin I. Clin Chim Acta 24 (1969) 353-357
15. Kincaid-Smith P., McMichael J., and Murphy E.A. The clinical course and pathology of hypertension with papilloedema (malignant hypertension). Q J Med 27 (1958) 117-153
16. Bali T., and Goldblatt H. On the pathogenesis of the vascular lesions of malignant hypertension in the rat; the role of elevated blood pressure and renal functional failure. Exp Med Surg 12 (1954) 460-479
17. Case D.B., Atlas S.A., Sullivan P.A., and Laragh J.H. Acute and chronic treatment of severe and malignant hypertension with the oral angiotensin-converting enzyme inhibitor captopril. Circulation 64 (1981) 765-771
18. Gavras H., Brown W.C., Brown J.J., Lever A.F., Linton A.L., MacAdam R.F., McNicol G.P., Robertson J.I., and Wardrop C. Microangiopathic hemolytic anemia and the development of the malignant phase of hypertension. Circ Res 28 Suppl II (1971) 127-141
19. Rocha R., Chander P.N., Zuckerman A., and Stier Jr. C.T. Role of aldosterone in renal vascular injury in stroke-prone hypertensive rats. Hypertension 33 (1999) 232-237
20. Rocha R., Chander P.N., Khanna K., Zuckerman A., and Stier Jr. C.T. Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats. Hypertension 31 (1998) 451-458
21. Chander P.N., Rocha R., Ranaudo J., Singh G., Zuckerman A., and Stier Jr. C.T. Aldosterone plays a pivotal role in the pathogenesis of thrombotic microangiopathy in SHRSP. J Am Soc Nephrol 14 (2003) 1990-1997
22. Kaplan N.M. Primary aldosteronism with malignant hypertension. N Engl J Med 269 (1963) 1282-1286
23. Aloia J.F., and Beutow G. Malignant hypertension with aldosteronoma producing adenoma. Am J Med Sci 268 (1974) 241-245
24. Zarifis J., Lip G.Y., Leatherdale B., and Beevers G. Malignant hypertension in association with primary aldosteronism. Blood Press 5 (1996) 250-254
25. Ideishi M., Kishikawa K., Kinoshita A., Sasaguri M., Ikeda M., Takebayashi S., and Arakawa K. High-renin malignant hypertension secondary to an aldosterone-producing adenoma. Nephron 54 (1990) 259-263
26. Oka K., Hayashi K., Nakazato T., Suzawa T., Fujiwara K., and Saruta T. Malignant hypertension in a patient with primary aldosteronism with elevated active renin concentration. Intern Med 36 (1997) 700-704
27. McLaren K.M., and MacDonald M.K. Histological and ultrastructural studies of the human juxtaglomerular apparatus in benign and malignant hypertension. J Pathol 139 (1983) 41-55
28. Hollenberg N.K., Epstein M., Basch R.I., Couch N.P., Hickler R.B., and Merrill J.P. Renin secretion in essential and accelerated hypertension. Am J Med 47 (1969) 855-859