Prevention of Salt-Induced Hypertension by an Analog of γ-Melanocyte-Stimulating Hormone in the Rat

American Journal of Hypertension

Volumn 20, Issue 8, 2007, Pages 862-865

  Ni, Xi Ping ^a   Humphreys, Michael H ^a  

^a SAN FRANCISCO GENERAL HOSPITAL   (United States)

Author keywords

dopaminergic; peptide hormone; pituitary function; Salt sensitive hypertension

Indexed keywords

BROMOCRIPTINE; GAMMA INTERMEDIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; AORTA PRESSURE; ARTICLE; HIGH SODIUM INTAKE; HORMONE DEFICIENCY; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; OSMOTIC PUMP; PRIORITY JOURNAL; RAT; TELEMETRY;

ANIMALS; BLOOD PRESSURE; BLOOD PRESSURE DETERMINATION; BROMOCRIPTINE; DISEASE MODELS, ANIMAL; DOPAMINE AGONISTS; FOLLOW-UP STUDIES; GAMMA-MSH; HORMONES; HYPERTENSION; INFUSION PUMPS, IMPLANTABLE; MALE; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHLORIDE, DIETARY; TELEMETRY; TREATMENT OUTCOME;

EID: 34547402522     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjhyper.2007.03.014     Document Type: Article

References (17)

1. Mayan H., Ling K.T., Lee E.Y., Wiedemann E., Kalinyak J.E., and Humphreys M.H. Dietary sodium intake modulates pituitary proopiomelanocortin mRNA abundance. Hypertension 28 (1996) 244-249
2. Humphreys M.H. Gamma-MSH, sodium metabolism, and salt-sensitive hypertension. Am J Physiol Regul Integr Comp Physiol 286 (2004) R417-R430
3. Mayan H., Ni X.P., Almog S., and Humphreys M.H. Suppression of gamma-melanocyte-stimulating hormone secretion is accompanied by salt-sensitive hypertension in the rat. Hypertension 42 (2003) 962-967
4. Ni X.P., Pearce D., Butler A.A., Cone R.D., and Humphreys M.H. Genetic disruption of gamma-melanocyte-stimulating hormone signaling leads to salt-sensitive hypertension in the mouse. J Clin Invest 111 (2003) 1251-1258
5. Sawyer T.K., Sanfilippo P.J., Hruby V.J., Engel M.H., Heward C.B., Burnett J.B., and Hadley M.E. 4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity. Proc Natl Acad Sci USA 77 (1980) 5754-5758
6. Chen X.W., Ying W.Z., Valentin J.P., Ling K.T., Lin S.Y., Wiedemann E., and Humphreys M.H. Mechanism of the natriuretic action of gamma-melanocyte-stimulating hormone. Am J Physiol 272 (1997) R1946-R1953
7. Ni X.P., Kesterson R.A., Sharma S.D., Hruby V.J., Cone R.D., Wiedemann E., and Humphreys M.H. Prevention of reflex natriuresis after acute unilateral nephrectomy by melanocortin receptor antagonists. Am J Physiol 274 (1998) R931-R938
8. Kok P., Roelfsema F., Frolich M., van Pelt J., Stokkel M.P., Meinders A.E., and Pijl H. Activation of dopamine D2 receptors simultaneously ameliorates various metabolic features of obese women. Am J Physiol Endocrinol Metab 291 (2006) E1038-E1043
9. Carey R.M., Van Loon G.R., Baines A.D., and Kaiser D.L. Suppression of basal and stimulated noradrenergic activities by the dopamine agonist bromocriptine in man. J Clin Endocrinol Metab 56 (1983) 595-602
10. Colao A., Di Sarno A., Guerra E., De Leo M., Mentone A., and Lombardi G. Drug insight: cabergoline and bromocriptine in the treatment of hyperprolactinemia in men and women. Nat Clin Pract Endocrinol Metab 2 (2006) 200-210
11. Stier Jr. C.T., Cowden E.A., and Allison M.E. Effects of bromocriptine on single nephron and whole-kidney function in rats. J Pharmacol Exp Ther 220 (1982) 366-370
12. Hussain T., Abdul-Wahab R., and Lokhandwala M.F. Bromocriptine stimulates Na+, K(+)-ATPase in renal proximal tubules via the cAMP pathway. Eur J Pharmacol 321 (1997) 259-263
13. Guyton A.C., Coleman T.G., Cowley Jr. A.V., Scheel K.W., Manning Jr. R.D., and Norman Jr. R.A. Arterial pressure regulation. Overriding dominance of the kidneys in long-term regulation and in hypertension. Am J Med 52 (1972) 584-594
14. Brooks V.L., Haywood J.R., and Johnson A.K. Translation of salt retention to central activation of the sympathetic nervous system in hypertension. Clin Exp Pharmacol Physiol 32 (2005) 426-432
15. Holtzman E.J., Braley L.M., Williams G.H., and Hollenberg N.K. Kinetics of sodium homeostasis in rats: rapid excretion and equilibration rates. Am J Physiol 254 (1988) R1001-R1006
16. Franchi F., Lazzeri C., Barletta G., Ianni L., and Mannelli M. Centrally mediated effects of bromocriptine on cardiac sympathovagal balance. Hypertension 38 (2001) 123-129
17. Sowers J.R. Dopaminergic control of circadian norepinephrine levels in patients with essential hypertension. J Clin Endocrinol Metab 53 (1981) 1133-1137