Preparation and characterization of biotinylated chitosan nanoparticles

Yaoxue Xuebao

Volumn 42, Issue 5, 2007, Pages 557-561

  Yao, Qian ^a   Hou, Shi Xiang ^b   Zhang, Xuan ^b   Zhao, Gang ^a   Gou, Xiao Jun ^a   You, Jin Zong ^c  

^a CHENGDU UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c ZHEJIANG INTERNATIONAL STUDIES UNIVERSITY   (China)

Author keywords

Biotinylated; Chitosan; HepG2 cell; Nanoparticle; Preparation

Indexed keywords

BIOTIN; BIOTINYL N HYDROXYSULFOSUCCINIMIDE ESTER; BIOTINYL-N-HYDROXYSULFOSUCCINIMIDE ESTER; CHITOSAN; DRUG CARRIER; DRUG DERIVATIVE; NANOPARTICLE; SUCCINIMIDE DERIVATIVE;

ARTICLE; BIOTINYLATION; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; HUMAN; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; PARTICLE SIZE; PATHOLOGY; TUMOR CELL LINE;

BIOTIN; BIOTINYLATION; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CHITOSAN; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; HUMANS; LIVER NEOPLASMS; NANOPARTICLES; PARTICLE SIZE; SUCCINIMIDES;

EID: 34547289646     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Yingjuan L, Philip SL. Folate-mediated delivery of macromolecular anticancertherapeutio agents [ J ]. Adv Drug Deliv Rev, 2002,54:675 -688.
2. Sakahara H, Saga T. Avidin-biotin system for delivery of diagnostic agents [ J]. Adv Drug Deliv Rev, 1999,37; 89-101.
3. 99Tc-DTPA-bis-Biotin in rat AS-30D-hepatoma cells [J]. NuclMed Bio, 2003, 30:135-140.
4. Kun N, Tae B. Self-assembled nanoparticles of hydrophobically-modified polysaccharide bearing vitamin H as a targeted anti-cancer drug delivery system [ J]. Eur J Pharm Sci, 2003,18:165-173.
5. Illum L, Jabbal-Gill I, Hinchcliffe M, et al. Chitosan as a novel nasal delivery system for vaccines [ J ]. Adv Drug Deliv Rev, 2001,51:81 -96.
6. Angela MDC, Alejandro S, María JA. Chitosan nanoparticles: a new vehicle for the improvement of the delivery of drugs to the ocular surface. Application to cyclosporin A [ J]. Int J Pharm, 2001, 224:159-168.
7. Janos Z, Donald MM. Chemical synthesis of biotinylated histories and analysis by sodium dodecyl sulfatepolyacrylamide gel electrophoresis/ streptavidin-peroxidase [J]. Arch Biochem Biophys, 1999,371:83-88.
8. Jameel A, Krishna KV. Determination of d-Biotin at the microgram level [J]. Talanta, 1979,26:1025 -1026.
9. Anthony EE, Charlene H. Liquid Chromatographie determination of biotin in multivitamin-multimineral tablets [J]. J Pharm Biomed Anal, 1998,16:1311 -1315.
10. Wilchek M, Bayer EA. The avidin-biotin complex in bioanalytical applications [J]. Anal Biochem, 1988,17; 11 -32.