Effect of a 40% chlorhexidine varnish on demineralization of dentin surfaces in situ

American Journal of Dentistry

Volumn 20, Issue 3, 2007, Pages 193-197

  Bizhang, Mozhgan ^a   Seemann, Rainer ^b   Römhild, Gregor ^b   Chun, Yong Hee P ^c   Umland, Niklas ^d   Lang, Hermann ^a   Zimmer, Stefan ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c UNIVERSITY OF MICHIGAN   (United States)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CERVITEC; CHLORHEXIDINE; DISINFECTANT AGENT; THYMOL; UNCLASSIFIED DRUG;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DENTAL SURGERY; DRUG COMBINATION; FEMALE; HUMAN; MALE; NONPARAMETRIC TEST; RADIOGRAPHY; RANDOMIZED CONTROLLED TRIAL; TOOTH DISEASE;

ADULT; ANALYSIS OF VARIANCE; CHLORHEXIDINE; DENTAL CAVITY LINING; DENTAL DISINFECTANTS; DRUG COMBINATIONS; FEMALE; HUMANS; MALE; STATISTICS, NONPARAMETRIC; THYMOL; TOOTH DEMINERALIZATION;

EID: 34547267791     PISSN: 08948275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Summney DL, Jordan HV. Characterization of bacteria isolated from human root surface caries. Arch Oral Biol 1974; 17: 343-351.
2. Clarkson JE. Epidemiology of root caries. Am J Dent 1995; 8: 329-334.
3. Jones JA. Root caries: Prevention and chemotherapy. Am J Dent 1995; 8: 352-357.
4. Bowden GH, Ekstrand J, McNaughton B, Challacombe SJ. Association of selected bacteria with the lesions of root surface caries. Oral Microbiol Immunol 1990; 5: 346-351.
5. Loesche WJ. Role of Streptococcus mutons in human dental decay. Microbiol Rev 1986; 50: 353-380.
6. 2 on glucan formation by salivary and culture supernatant GTF adsorbed to hydroxyapatite. Scand J Dent Res 1987; 95: 532-535.
7. Rolla G, Melsen B. On the mechanism of the plaque inhibition by chlorhexidine. J Dent Res 1975; 54 (Sp Is B): 57-62.
8. Emilson CG. Outlook for Hibitane in dental caries. J Clin Periodontol 1977; 4: 136-143.
9. Kidd EA. Role of chlorhexidine in the management of dental caries. Int Dent J 1991; 41: 279-286.
10. Loesche WJ. Antimicrobials, can they be effective? In: Guggenheim B. Cariology today. Zürich: Karger; 1984. 293-300.
11. Meurman JH. Chemotherapy of Streptococcus mutons. Proc Finn Dent Soc 1986; 82: 305-311.
12. Emilson CG. Effect of chlorhexidine gel treatment on Streptococcus mutons population in human saliva and dental plaque. Scand J Dent Res 1981; 89: 239-246.
13. Maltz M, Zickert I, Krasse B. Effect of intensive treatment with chlorhexidine on number of Streptococcus mutans in saliva. Scand J Dent Res 1981; 89: 445-449.
14. Zickert I, Emilson CG, Ekblom K, Krasse B. Prolonged oral reduction of Streptococcus mutons in humans after chlorhexidine disinfection followed by fluoride treatment. Scand J Dent Res 1987; 95: 315-319.
15. Bratthall D, Serinirach R, Rapisuwon S, Kuratana M, Luangjarmekorn V, Luksila K, Chaipanich P. A study into the prevention of fissure caries using an antimicrobial varnish. Int Dent J 1995; 45: 245-254.
16. Joharji RM, Adenubi JO. Prevention of pit and fissure caries using an antimicrobial varnish: 9 month clinical evaluation. J Dent 2001; 29: 247-254.
17. Splieth C, Steffen H, Rosin M, Welk A. Caries prevention with chlorhexidine-thymol varnish in high risk schoolchildren. Community Dent Oral Epidemiol 2000; 28: 419-423.
18. Twetman S, Petersson LG. Interdental caries incidence and progression in relation to mutans streptococci suppression after chlorhexidine-thymol varnish treatments in schoolchildren. Acta Odontol Scand 1999; 57: 144-148.
19. Petersson LG, Magnusson K, Andersson H, Almquist B, Twetman S. Effect of quarterly treatments with a chlorhexidine and a fluoride varnish on approximal caries in caries-susceptible teenagers: A 3-year clinical study. Caries Res 2000; 34: 140-143.
20. Petersson LG, Magnusson K, Andersson H, Deierboig G, Twetman S. Effect of semi-annual applications of a chlorhexidirie/fluoride varnish mixture on approximal caries incidence in schoolchildren. A three-year radiographic study. Eur J Oral Sci 1998; 106: 623-627.
21. Ie YL, Schaeken MJ. Effect of single and repeated application of chlorhexidine varnish on mutans streptococci in plaque from fissures of premolar and molar teeth. Caries Res 1993; 27: 303-306.
22. Persson RE, Truelove EL, LeResche L, Robinovitch MR. Therapeutic effects of daily or weekly chlorhexidine rinsing on oral health of a geriatric population. Oral Surg Oral Med Oral Pathol 1991; 72: 184-191.
23. Sandham HJ, Brown J, Chan KH, Phillips HI, Burgess RC, Stokl AJ. Clinical trial in adults of an antimicrobial varnish for reducing mutans streptococci. J Dent Res 1991; 70: 1401-1408.
24. Schaeken MJ, Keltjens HM, van der Hoeven JS. Effects of fluoride and chlorhexidine on the microflora of dental root surfaces and progression of root-surface caries. J Dent Res 1991; 70: 150-153.
25. Schaeken MJ, van der Hoeven JS, Hendriks JC. Effects of varnishes containing chlorhexidine on the human dental plaque flora. J Dent Res 1989; 68: 1786-1789.
26. Twetman S, Hallgren A, Petersson LG. Effect of an antibacterial varnish on mutans streptococci in plaque from enamel adjacent to orthodontic appliances. Caries Res 1995; 29: 188-191.
27. Arends J, Duschner H, Ruben JL. Penetration of varnishes into demineralized root dentine in vitro. Caries Res 1997; 31: 201-205.
28. Balanyk TE, Sandham HJ. Development of sustained-release antimicrobial dental varnishes effective against Streptococcus mutans in vitro. J Dent Res 1985; 64: 1356-1360.
29. Huizinga ED, Ruben J, Arends J. Effect of an antimicrobial-containing varnish on root demineralisation in situ. Caries Res 1990; 24: 130-132.
30. Schaeken MJ, de Haan P. Effects of sustained-release chlorhexidine acetate on the human dental plaque flora. J Dent Res 1989; 68: 119-123.
31. van Lunsen DM, de Soet JJ, Weerheijm KL, Groen HJ, Veerkamp JS. Effects of dental treatment and single application of a 40% chlorhexidine varnish on mutans Streptococci in young children under intravenous anaesthesia. Caries Res 2000; 34: 268-274.
32. Keltjens HM, Creugers TJ, Schaeken MJ, Van der Hoeven JS. Effects of chlorhexidine-containing gel and varnish on abutment teeth in patients with overdentures. J Dent Res 1992; 71: 1582-1186.
33. Pienihakkinen K, Soderling E, Ostela I, Leskela I, Tenovuo J. Comparison of the efficacy of 40% chlorhexidine varnish and 1% chlorhexidine-fluoride gel in decreasing the level of salivary mutans streptococci. Caries Res 1995; 29: 62-67.
34. Sandham HJ, Brown J, Phillips HI, Chan KH. A preliminary report of long-term elimination of detectable mutans streptococci in man. J Dent Res 1988; 67: 9-14.
35. de Josselin de Jong E, ten Bosch JJ, Noordmans J. Optimised microcomputer-guided quantitative microradiography on dental mineralised tissue slices. Phys Med Biol 1987; 32: 887-899.
36. Bortz J. Statistics for social scientists. 1993: Berlin:Springer, p.374. (In German).
37. Huizinga ED, Ruben JL, Arends J. Chlorhexidine and thymol release from a varnish system. J Biol Buccale 1991; 19: 343-348.
38. Marren PV, Lynch E, Heath MR. Cervitec's effect on plaque mutans streptococci covering health root surfaces. J Dent Res 1997; 76: 93 (Abstr 635).
39. Sandham HJ, Brown J, Chan KH. Clinical elimination of Streptococcus mutans with Chlorzoin and polyurethane varnishes. J Dent Res 1985; 64: 213 (Abstr 343).
40. Weiger R, Friedrich C, Netuschil L, Schlagenhauf U. Effect of chlorhexidine-containing varnish (Cervitec) on microbial vitality and accumulation of supragingival dental plaque in humans. Caries Res 1994; 28: 267-271.
41. van Loveren C, Buijs JF, Buijs MJ, ten Cate JM. Protection of bovine enamel and dentine by chlorhexidine and fluoride varnishes in a bacterial demineralization model. Caries Res 1996; 30: 45-51.