Interactions of primary neuroepithelial progenitor and brain endothelial cells: Distinct effect on neural progenitor maintenance and differentiation by soluble factors and direct contact

Cell Research

Volumn 17, Issue 7, 2007, Pages 619-626

  Sosa, Miguel A Gama ^a,c   De Gasperi, Rita ^a,c   Rocher, Anne B ^b   Perez, Gissel M ^a,c   Simons, Keila ^a,c   Cruz, Daniel E ^a,c   Hof, Patrick R ^b   Elder, Gregory A ^a,c  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Culture; Differentiation; Endothelial cells; Neuroepithelial cells

Indexed keywords

CD31 ANTIGEN; FIBRONECTIN; VON WILLEBRAND FACTOR;

ANIMAL; ARTICLE; BRAIN; CELL CULTURE; CELL DIFFERENTIATION; COCULTURE; CONFOCAL MICROSCOPY; CYTOLOGY; ENDOTHELIUM CELL; METABOLISM; MOUSE; NEUROEPITHELIUM; PHYSIOLOGY; PRENATAL DEVELOPMENT; STEM CELL;

ANIMALS; ANTIGENS, CD31; BRAIN; CELL DIFFERENTIATION; CELLS, CULTURED; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; FIBRONECTINS; MICE; MICROSCOPY, CONFOCAL; NEUROEPITHELIAL CELLS; STEM CELLS; VON WILLEBRAND FACTOR;

EID: 34547226651     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2007.53     Document Type: Article

References (18)

1. Harrigan MR. Angiogenic factors in the central nervous system. Neurosurgery 2003; 53:639-660.
2. Autiero M, De Smet F, Claes F, Carmeliet P. Role of neural guidance signals in blood vessel navigation. Cardiovasc Res 2005; 65:629-638.
3. Eichmann A, Le Noble F, Autiero M, Carmeliet P. Guidance of vascular and neural network formation. Curr Opin Neurobiol 2005; 15:108-115.
4. Eichmann A, Makinen T, Alitalo K. Neural guidance molecules regulate vascular remodeling and vessel navigation. Genes Dev 2005; 19:1013-1021.
5. Park JA, Choi KS, Kim SY, Kim KW Coordinated interaction of the vascular and nervous systems: from molecule-to cell-based approaches. Biochem Biophys Res Commun 2003; 311:247-253.
6. Storkebaum E, Lambrechts D, Carmeliet P. VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection. Bioessays 2004; 26:943-954.
7. Ward NL, LaManna JC. The neurovascular unit and its growth factors: coordinated response in the vascular and nervous systems. Neurol Res 2004; 26:870-883.
8. Raab S, Beck H, Gaumann A, et al. Impaired brain angiogenesis and neuronal apoptosis induced by conditional homozygous inactivation of vascular endothelial growth factor. Thromb Haemost 2004; 91:595-605.
9. Alvarez-Buylla A, Lim DA. For the long run: maintaining germinal niches in the adult brain. Neuron 2004; 41:683-686.
10. Shen Q, Goderie SK, Jin L, et al. Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science 2004; 304:1338-1340.
11. Song L, Pachter JS. Culture of murine brain microvascular endothelial cells that maintain expression and cytoskeletal association of tight junction-associated proteins. In Vitro Cell Dev Biol Anim 2003; 39:313-320.
12. Voyta JC, Via DP, Butterfield CE, Zetter BR. Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein. J Cell Biol 1984; 99:2034-2040.
13. Ali SA, Pappas IS, Parnavelas JG. Collagen type IV promotes the differentiation of neuronal progenitors and inhibits astroglial differentiation in cortical cell cultures. Dev Brain Res 1998; 110:31-38.
14. Lo EH, Dalkara T, Moskowitz MA. Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci 2003; 4:399-415.
15. Jung SS, Levy E. Murine cerebrovascular cells as a cell culture model for cerebral amyloid angiopathy: isolation of smooth muscle and endothelial cells from mouse brain. Methods Mol Biol 2005; 299:211-219.
16. Schiera G, Sala S, Gallo A, et al. Permeability properties of a three-cell type in vitro model of blood-brain barrier. J Cell Mol Med 2005; 9:373-379.
17. Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 2000; 6:389-395.
18. Risau W. Mechanisms of angiogenesis. Nature 1997; 386:671-674.