Rapid systemic uptake of allergens through the respiratory mucosa

Journal of Allergy and Clinical Immunology

Volumn 120, Issue 2, 2007, Pages 472-474

  Hens, Greet ^a,b   Bobic, Sonja ^a   Reekmans, Kristien ^a   Ceuppens, Jan Louis ^a,c   Hellings, Peter Wim ^a,b  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b Oto Rhino Laryngology ^*  (United States)

^c UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; HORSERADISH PEROXIDASE; OVALBUMIN;

ABSORPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BRONCHUS; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; LETTER; LOWER RESPIRATORY TRACT; LUNG ALVEOLUS; LUNG BLOOD VESSEL; MACROMOLECULE; MALE; MOUSE; NONHUMAN; NOSE CAVITY; NOSE MUCOSA; PRIORITY JOURNAL; RESPIRATORY TRACT INFLAMMATION; RESPIRATORY TRACT MUCOSA; TRACHEA; TRACHEOTOMY; UPPER RESPIRATORY TRACT;

ABSORPTION; ALLERGENS; ANIMALS; BRONCHI; INFLAMMATION; MALE; MICE; MICE, INBRED BALB C; NASAL CAVITY; OVALBUMIN; RESPIRATORY MUCOSA; TIME FACTORS;

EID: 34547222550     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2007.03.047     Document Type: Letter

References (9)

1. Greiff L., and Persson C.G.A. On the physiology of airway absorption of allergens. Allergy 54 (1999) 31-36
2. Greiff L., Wollmer P., Svensson C., Andersson M., and Persson C.G. Effect of seasonal allergic rhinitis on airway mucosal absorption of chromium-51 labelled EDTA. Thorax 48 (1993) 648-650
3. Greiff L., Lundin S., Svensson C., Andersson M., Wollmer P., and Persson C.G.A. Reduced airway absorption in seasonal allergic rhinitis. Am J Respir Crit Care Med 156 (1997) 783-786
4. Passalacqua G., Altrinetti V., Mariani G., Falagiani P., Mistrello G., Brizzolara R., et al. Pharmacokinetics of radiolabelled Par j 1 administered intranasally to allergic and healthy subjects. Clin Exp Allergy 35 (2005) 880-883
5. Togias A. Systemic effects of local allergic disease. J Allergy Clin Immunol 2004 suppl (2006) S1-S8
6. Beeh K.M., Beier J., Kornmann O., Meier C., Taeumer T., and Buhl R. A single nasal allergen challenge increases induced sputum inflammatory markers in non-asthmatic subjects with seasonal allergic rhinitis: correlation with plasma interleukin-5. Clin Exp Allergy 33 (2003) 475-482
7. Li J., Saito H., Crawford L., Inman M.D., Cyr M.M., and Denbrug J.A. Haemopoietic mechanisms in murine allergic upper and lower airway inflammation. Immunology 114 (2005) 386-396
8. Hellings P.W., Hessel E.M., Van Den Oord J.J., Kasran A., Van Hecke P., and Ceuppens J.L. Eosinophilic rhinitis accompanies the development of lower airway inflammation and hyperreactivity in sensitized mice exposed to aerosolized allergen. Clin Exp Allergy 31 (2001) 782-790
9. Seayuong J., Namju K., Soonkwan H., Euigee H., and Yang-gi M. Horseradish peroxidase permeability across rat nasal mucosa in selective stimulation of substance P innervation with capsaicin. Ann Otol Rhinol Laryngol 104 (1995) 895-898