A small dopamine permeability of storage vesicle membranes and end product inhibition of tyrosine hydroxylase are sufficient to explain changes occurring in dopamine synthesis and storage after inhibition of neuron firing

Synapse

Volumn 61, Issue 9, 2007, Pages 715-723

  Wallace, Lane J ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b NONE   (United States)

Author keywords

Computational model; Striatum

Indexed keywords

DOPAMINE TRANSPORTER; NEUROTRANSMITTER; TYROSINE 3 MONOOXYGENASE;

ARTICLE; COMPUTER SIMULATION; CYTOSOL; DOPAMINE METABOLISM; DOPAMINERGIC NERVE CELL; ENZYME INHIBITION; EXOCYTOSIS; NONHUMAN; PRIORITY JOURNAL; SYNAPSE; VARICOSIS;

ANIMALS; DOPAMINE; METABOLIC NETWORKS AND PATHWAYS; MODELS, NEUROLOGICAL; NEURAL INHIBITION; NEURONS; PROTEIN TRANSPORT; TIME FACTORS; TYROSINE 3-MONOOXYGENASE; VESICULAR MONOAMINE TRANSPORT PROTEINS;

EID: 34547217486     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20408     Document Type: Article

References (47)

1. Aghajanian GK, Roth RH. 1970. γ-Hydroxybutyrate-induced increase in brain dopamine: Localization by fluorescence microscopy. J Pharmacol Exp Ther 175:131-137.
2. Anden NE, Magnusson T, Stock G. 1973. Effects of drugs influencing monoamine mechanisms on the increase in brain dopamine produced by axotomy or treatment with γ hydroxybutyric acid. Naunyn Schmiedeberg's Arch Pharmacol 278:363-372.
3. Anden NE, Fuxe K, Hamberger B, Hokfelt T. 1966. A quantitative study on the nigro-neostriatal dopamine neuron system in the rat. Acta Physiol Scand 67:306-312.
4. Bannon MJ, Michaud RL, Roth RH. 1981. Mesocortical dopamine neurons. Lack of autoreceptors modulating dopamine synthesis. Mol Pharmacol 19:270-275.
5. Bannon MJ, Wolfe ME, Roth RH. 1983. Pharmacology of dopamine neurons innervating the prefrontal, cingulate and piriform cortices. Eur J Pharmacol 91:119-125.
6. 3H]GBR 12783 binding to a specific site associated with the neuronal dopamine uptake complex in the central nervous system. Eur J Pharmacol 126:211-222.
7. Bunney BS, Aghajanian GK, Roth RH. 1973. Comparison of effects of L-DOPA, amphetamine and apomorphine on firing rate of rat dopaminergic neurons. Nat New Biol 245:123-125.
8. Chen NH, Ding JH, Wang YL, Reith MEA. 1997. Potential misconceptions in dopamine transporter assays arising from the binding of [I-125]RTI-121 to filters: Effect of ions and cocaine. J Neurosci Methods 75:179-186.
9. Darchen F, Masuo Y, Vial M, Rostene W, Scherman D. 1989. Quantitative autoradiography of the rat-brain vesicular monoamine transporter using the binding of [H-3] dihydrotetrabenazine and 7-amino-8-[I-125]iodoketanserin. Neuroscience 33:341-349.
10. Demarest KT, Moore KE. 1979. Comparison of dopamine synthesis regulation in the terminals of nigrostriatal, mesolimbic, tuberoinfundibular and tuberohypophyseal neurons. J Neural Transm 46:263-277.
11. Demarest KT, Lawson-Wendling KL, Moore KE. 1983. d-Amphetamine and γ-butyrolactone alteration of dopamine synthesis in the terminals of nigrostriatal and mesolimbic neurons. Possible role of various autoreceptor sensitivities. Biochem Pharmacol 32:691-697.
12. Doucet G, Descarries L, Garcia S. 1986. Quantification of the dopamine innervation in adult-rat neostriatum. Neuroscience 19:427-445.
13. 3H]nomifensine to striatal membranes. Biochem Pharmacol 34:1137-1144.
14. Dunkley PR, Bobrovskaya L, Graham ME, von Nagy-Felsobuki EI, Dickson PW. 2004. Tyrosine hydroxylase phosphorylation: Regulation and consequences. J Neurochem 91:1025-1043.
15. Floor E, Leventhal PS, Wang Y, Meng L, Chen WQ. 1995. Dynamic storage of dopamine in rat brain synaptic vesicles in vitro. J Neurochem 64:689-699.
16. Glick SD, Dong N, Keller RW, Carlson JN. 1994. Estimating extracellular concentrations of dopamine and 3,4-dihydroxyphenylacetic acid in nucleus-accumbens and striatum using microdialysis - Relationships between in vitro and in vivo recoveries. J Neurochem 62:2017-2021.
17. Gu H, Wall SC, Rudnick G. 1994. Stable expression of biogenicamine transporters reveals differences in inhibitor sensitivity, kinetics, and ion dependence. J Biol Chem 269:7124-7130.
18. 3H]GBR-12935 binding in brain: A radioligand for selective labelling of thedopamine transport complex. J Neurochem 46:1272-1276.
19. Janowsky A, Mah C, Johnson RA, Cunningham CL, Phillips TJ, Crabbe JC, Eshleman AJ, Belknap JK. 2001. Mapping genes that regulate density of dopamine transporters and correlated behaviors in recombinant inbred mice. J Pharmacol Exp Ther 298:634-643.
20. Johnson RG Jr. 1988. Accumulation of biological amines into chromaffine granules: A model for hormone and neurotransmitter transport. Physiol Rev 68:232-307.
21. Jones SR, Gainetdinov RR, Jaber M, Giros B, Wightman RM, Caron MG. 1998. Profound neuronal plasticity in response to inactivation of the dopamine transporter. Proc Natl Acad Sci USA 95:4029-4034.
22. Jones SR, Joseph JD, Barak LS, Caron MG, Wightman RM. 1999. Dopamine neuronal transport kinetics and effects of amphetamine. J Neurochem 73:2406-2414.
23. Kalivas PW, Duffy P. 1993. Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals. J Neurosci 13:266-275.
24. Kilbourn M, Frey K. 1996. Striatal concentrations of vesicular monoamine transporters are identical in MPTP-sensitive (C57BL/6) and -insensitive (CD-1) mouse strains. Eur J Pharmacol 307:227-232.
25. Kilts CD, Anderson CM, Ely TD, Nishita JK. 1987. Absence of synthesis-modulating nerve-terminal autoreceptors on mesoamygdaloid and other mesolimbic dopamine neuronal populations. J Neurosci 7:3961-3975.
26. 3 receptor mutant mice. J Neurosci 18:2231-2238.
27. Liljequist S, Engel J. 1979. Attenuation of the γ-butyrolactone- induced increase in DOPA accumulation by chronic ethanol administration. J Neural Transm 46:195-204.
28. Lindgren N, Xu ZQD, Herrera-Marschitz M, Haycock J, Hokfelt T, Fisone G. 2001. Dopamine D-2 receptors regulate tyrosine hydroxylase activity and phosphorylation at Ser40 in rat striatum. Eur J Neurosci 13:773-780.
29. Lindgren N, Usiello A, Goiny M, Haycock J, Erbs E, Greengard P, Hokfelt T, Borrelli E, Fisone G. 2003. Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sites. Proc Natl Acad Sci USA 100:4305-4309.
30. Marshall JF, Odell SJ, Navarrete R, Rosenstein AJ. 1990. Dopamine high-affinity transport site topography in rat-brain - Major differences between dorsal and ventral striatum. Neuroscience 37:11-21.
31. McMillen BA, Shore PA. 1980. Role of dopamine storage function in the control of rat striatal tyrosine hydroxylase activity. Naunyn Schmiedebergs Arch Pharmacol 313:39-44.
32. Nagatsu T, Levitt M, Udenfriend S. 1964. Tyrosine hydroxylase: The initial step in norepinephrine biocynthesis. J Biol Chem 239:2910-2917.
33. Near JA, Bigelow JC, Wightman RM. 1988. Comparison Of uptake of dopamine in rat striatal chopped tissue and synaptosomes. J Pharmacol Exp Ther 245:921-927.
34. Partilla JS, Dempsey AG, Nagpal AS, Blough BE, Baumann MH, Rothman RB. 2006. Interaction of amphetamines and related compounds at the vesicular monoamine transporter. J Pharmacol Exp Ther 319:237-246.
35. Rehavi M, Goldin M, Roz N, Weizman A. 1998. Regulation of rat brain vesicular monoamine transporter by chronic treatment with ovarian hormones. Mol Brain Res 57:31-37.
36. Roth RH, Walters JR, Aghajanian GK. 1973.Effect of impulse flow on the release and synthesis of DA in the rat striatum. In: Usdin E, Snyder SH, editors. Frontiers in catecholamine research. New York: Pergamon Press. p 556-574.
37. Rothman RB, Cadet JL, Akunne HC, Silverthorn ML, Baumann MH, Carroll FI, Rice KC, Decosta BR, Partilla JS, Wang JB, Uhl G, Glowa JR, Dersch CM. 1994. Studies of the biogenic-amine transporters. IV. Demonstration of a multiplicity of binding-sites in rat caudate membranes for the cocaine analog [I-125] Rti-55. J Pharmacol Exp Ther 270:296-309.
38. Scherman D. 1986. Dihydrotetrabenazine binding and monoamine uptake in mouse-brain regions. J Neurochem 47:331-339.
39. Scherman D, Boschi G. 1988. Time required for transmitter accumulation inside monoaminergic storage-vesicles differs in peripheral and in central systems. Neuroscience 27:1029-1035.
40. Scherman D, Boschi G, Rips R, Henry JP. 1986. The regionalization of [H-3] dihydrotetrabenazine binding-sites in the mouse-brain and its relationship to the distribution of monoamines and their metabolites. Brain Res 370:176-181.
41. Sitte HH, Huck S, Reither H, Boehm S, Singer EA, Pifl C. 1998. Carrier-mediated release, transport rates, and charge transfer induced by amphetamine, tyramine, and dopamine in mammalian cells transfected with the human dopamine transporter. J Neurochem 71:1289-1297.
42. Takahashi N, Miner LL, Sora I, Ujike H, Revay RS, Kostic V, Jackson-Lewis V, Przedborski S, Uhl GR. 1997. VMAT2 knockout mice: Heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity. Proc Natl Acad Sci USA 94:9938-9943.
43. Walters JR, Roth RH. 1972. Effect of gamma-hydroxybutyrate on dopamine and dopamine metabolites in the rat striatum. Biochem Pharmacol 21:2111-2121.
44. Walters JR, Roth RH. 1974. Dopaminergic neurons: Drug-induced antagonism of the increase in tyrosine hydroxylase activity produced by cessation of impulse flow. J Pharmacol Exp Ther 191:82-91.
45. Walters JR, Roth RH. 1976. Dopaminergic neurons: An in vivo system for measuring drug interactions with presynaptic receptors. Naunyn Schmiedebergs Arch Pharmacol 296:5-14.
46. Walters JR, Aghajanian GK, Roth RH. 1972. Dopaminergic neurons: Inhibition of firing by γ-hydroxybutyrate. In: Bloom FE, Acheson GH, editors. Proceedings of the Fifth International Congress on Pharmacology. Basal: Karger. p 246.
47. Walters JR, Roth RH, Aghajanian GK. 1973. Dopaminergic neuron: Similar biochemical and histochemical effects of γ-hydroxybuty-rate and acute lesions of the nigro-neostriatal pathway. J Pharmacol Exp Ther 186:630-639.