Selective oxidation of Zn2+ - Insulin catalyzed by Cu 2+

Journal of Pharmaceutical Sciences

Volumn 96, Issue 7, 2007, Pages 1844-1847

  Sadineni, Vikram ^a   Schöneich, Christian ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

Formulation; Mass spectrometry; Oxidation; Proteins; Stability

Indexed keywords

ASCORBIC ACID; CHROMIUM; COBALT; COPPER ION; HISTIDINE; IRON; MANGANESE; NICKEL; RECOMBINANT HUMAN INSULIN; ZINC ION; ANTIDIABETIC AGENT; ANTIOXIDANT; COPPER; INSULIN; PROTEIN SUBUNIT; RECOMBINANT PROTEIN; ZINC;

ARTICLE; CATALYSIS; DRUG FORMULATION; DRUG STABILITY; DRUG STRUCTURE; INTERMETHOD COMPARISON; OXIDATION; OXIDATION REDUCTION REACTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN;

ANTIOXIDANTS; ASCORBIC ACID; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COPPER; HISTIDINE; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; ZINC;

EID: 34547199495     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.20834     Document Type: Article

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