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Volumn 212, Issue 7, 2007, Pages 537-547

IL-21 enhances dendritic cell ability to induce interferon-γ production by natural killer T cells

Author keywords

Cytokine production; Dendritic cells; IFN ; IL 21; NKT cells

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; CD1D ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 21; INTERLEUKIN 4;

EID: 34547156550     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2007.03.007     Document Type: Article
Times cited : (24)

References (57)
  • 1
    • 0242580118 scopus 로고    scopus 로고
    • Different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos
    • Agrawal S., Agrawal A., Doughty B., Gerwitz A., Blenis J., Van D.T., and Pulendran B. Different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. J. Immunol. 171 (2003) 4984-4989
    • (2003) J. Immunol. , vol.171 , pp. 4984-4989
    • Agrawal, S.1    Agrawal, A.2    Doughty, B.3    Gerwitz, A.4    Blenis, J.5    Van, D.T.6    Pulendran, B.7
  • 2
    • 0026645233 scopus 로고
    • An NK1.1+CD4+8- single-positive thymocyte subpopulation that expresses a highly skewed T-cell antigen receptor Vβ family
    • Arase H., Arase N., Ogasawara K., Good R.A., and Onoé K. An NK1.1+CD4+8- single-positive thymocyte subpopulation that expresses a highly skewed T-cell antigen receptor Vβ family. Proc. Natl. Acad. Sci. USA 89 (1992) 6506-6510
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6506-6510
    • Arase, H.1    Arase, N.2    Ogasawara, K.3    Good, R.A.4    Onoé, K.5
  • 3
  • 4
    • 0028352752 scopus 로고
    • Cytotoxicity of fresh NK1.1+ T cell receptor α/β+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target
    • Arase H., Arase N., Kobayashi Y., Nishimura Y., Yonehara S., and Onoé K. Cytotoxicity of fresh NK1.1+ T cell receptor α/β+ thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target. J. Exp. Med. 180 (1994) 423-432
    • (1994) J. Exp. Med. , vol.180 , pp. 423-432
    • Arase, H.1    Arase, N.2    Kobayashi, Y.3    Nishimura, Y.4    Yonehara, S.5    Onoé, K.6
  • 5
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J., and Steinman R.M. Dendritic cells and the control of immunity. Nature 392 (1998) 245-252
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 6
    • 0842278642 scopus 로고    scopus 로고
    • IL-21 induces the functional maturation of murine NK cells
    • Brady J., Hayakawa Y., Smyth M.J., and Nutt S.L. IL-21 induces the functional maturation of murine NK cells. J. Immunol. 172 (2004) 2048-2058
    • (2004) J. Immunol. , vol.172 , pp. 2048-2058
    • Brady, J.1    Hayakawa, Y.2    Smyth, M.J.3    Nutt, S.L.4
  • 7
    • 0345257344 scopus 로고    scopus 로고
    • Interleukin-21 inhibits dendritic cell activation and maturation
    • Brandt K., Bulfone-Paus S., Foster D.C., and Ruckert R. Interleukin-21 inhibits dendritic cell activation and maturation. Blood 102 (2003) 4090-4098
    • (2003) Blood , vol.102 , pp. 4090-4098
    • Brandt, K.1    Bulfone-Paus, S.2    Foster, D.C.3    Ruckert, R.4
  • 8
    • 0034332450 scopus 로고    scopus 로고
    • Generation of murine dendritic cells from flt3-ligand-supplemented bone marrow cultures
    • Brasel K., De Smedt T., Smith J.L., and Maliszewski C.R. Generation of murine dendritic cells from flt3-ligand-supplemented bone marrow cultures. Blood 96 (2000) 3029-3039
    • (2000) Blood , vol.96 , pp. 3029-3039
    • Brasel, K.1    De Smedt, T.2    Smith, J.L.3    Maliszewski, C.R.4
  • 9
    • 0035478713 scopus 로고    scopus 로고
    • Histamine polarizes human dendritic cells into Th2 cell-promoting effector dendritic cells
    • Caron G., Delneste Y., Roelandts E., Duez C., Bonnefoy J.Y., Pestel J., and Jeannin P. Histamine polarizes human dendritic cells into Th2 cell-promoting effector dendritic cells. J. Immunol. 167 (2001) 3682-3686
    • (2001) J. Immunol. , vol.167 , pp. 3682-3686
    • Caron, G.1    Delneste, Y.2    Roelandts, E.3    Duez, C.4    Bonnefoy, J.Y.5    Pestel, J.6    Jeannin, P.7
  • 10
    • 2942755979 scopus 로고    scopus 로고
    • T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells
    • Chtanova T., Tangye S.G., Newton R., Frank N., Hodge M.R., Rolph M.S., and Mackay C.R. T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells. J. Immunol. 173 (2004) 68-78
    • (2004) J. Immunol. , vol.173 , pp. 68-78
    • Chtanova, T.1    Tangye, S.G.2    Newton, R.3    Frank, N.4    Hodge, M.R.5    Rolph, M.S.6    Mackay, C.R.7
  • 12
    • 1842477227 scopus 로고    scopus 로고
    • A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells
    • Dillon S., Agrawal A., Dyke T.V., Landreth G., McCauley L., Koh A., Maliszewski C., Akira S., and Pulendran B. A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells. J. Immunol. 172 (2004) 4733-4743
    • (2004) J. Immunol. , vol.172 , pp. 4733-4743
    • Dillon, S.1    Agrawal, A.2    Dyke, T.V.3    Landreth, G.4    McCauley, L.5    Koh, A.6    Maliszewski, C.7    Akira, S.8    Pulendran, B.9
  • 13
    • 0027239843 scopus 로고
    • Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes
    • Finkelman F.D., Madden K.B., Morris S.C., Holmes J.M., Boiani N., Katona I.M., and Maliszewski C.R. Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes. J. Immunol. 151 (1993) 1235-1244
    • (1993) J. Immunol. , vol.151 , pp. 1235-1244
    • Finkelman, F.D.1    Madden, K.B.2    Morris, S.C.3    Holmes, J.M.4    Boiani, N.5    Katona, I.M.6    Maliszewski, C.R.7
  • 14
    • 0036735859 scopus 로고    scopus 로고
    • Prolonged IFN-γ-producing NKT response induced with α-galactosylceramide-loaded DCs
    • Fujii S., Shimizu K., Kronenberg M., and Steinman R.M. Prolonged IFN-γ-producing NKT response induced with α-galactosylceramide-loaded DCs. Nat. Immunol. 3 (2002) 867-874
    • (2002) Nat. Immunol. , vol.3 , pp. 867-874
    • Fujii, S.1    Shimizu, K.2    Kronenberg, M.3    Steinman, R.M.4
  • 16
    • 0030781916 scopus 로고    scopus 로고
    • Dendritic cells: unique leukocyte populations which control the primary immune response
    • Hart D.N. Dendritic cells: unique leukocyte populations which control the primary immune response. Blood 90 (1997) 3245-3287
    • (1997) Blood , vol.90 , pp. 3245-3287
    • Hart, D.N.1
  • 17
    • 0034970326 scopus 로고    scopus 로고
    • Critical contribution of IFN-γ and NK cells, but not perforin-mediated cytotoxicity, to anti-metastatic effect of α-galactosylceramide
    • Hayakawa Y., Takeda K., Yagita H., Kakuta S., Iwakura Y., Van Kaer L., Saiki I., and Okumura K. Critical contribution of IFN-γ and NK cells, but not perforin-mediated cytotoxicity, to anti-metastatic effect of α-galactosylceramide. Eur. J. Immunol. 31 (2001) 1720-1727
    • (2001) Eur. J. Immunol. , vol.31 , pp. 1720-1727
    • Hayakawa, Y.1    Takeda, K.2    Yagita, H.3    Kakuta, S.4    Iwakura, Y.5    Van Kaer, L.6    Saiki, I.7    Okumura, K.8
  • 18
    • 0343618469 scopus 로고    scopus 로고
    • Differential expression of NK T cell Vα24JαQ invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy
    • Illés Z., Kondo T., Newcombe J., Oka N., Tabira T., and Yamamura T. Differential expression of NK T cell Vα24JαQ invariant TCR chain in the lesions of multiple sclerosis and chronic inflammatory demyelinating polyneuropathy. J. Immunol. 164 (2000) 4375-4381
    • (2000) J. Immunol. , vol.164 , pp. 4375-4381
    • Illés, Z.1    Kondo, T.2    Newcombe, J.3    Oka, N.4    Tabira, T.5    Yamamura, T.6
  • 19
    • 0034689004 scopus 로고    scopus 로고
    • The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli
    • Inaba K., Turley S., Iyoda T., Yamaide F., Shimoyama S., Reis e Sousa C., Germain R.N., Mellman I., and Steinman R.M. The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli. J. Exp. Med. 191 (2000) 927-936
    • (2000) J. Exp. Med. , vol.191 , pp. 927-936
    • Inaba, K.1    Turley, S.2    Iyoda, T.3    Yamaide, F.4    Shimoyama, S.5    Reis e Sousa, C.6    Germain, R.N.7    Mellman, I.8    Steinman, R.M.9
  • 20
    • 0035869436 scopus 로고    scopus 로고
    • Defective development of NK1.1+ T-cell antigen receptor áâ+ cells in zeta-associated protein 70 null mice with an accumulation of NK1.1+ CD3- NK-like cells in the thymus
    • Iwabuchi K., Iwabuchi C., Tone S., Itoh D., Tosa N., Negishi I., Ogasawara K., Uede T., and Onoé K. Defective development of NK1.1+ T-cell antigen receptor áâ+ cells in zeta-associated protein 70 null mice with an accumulation of NK1.1+ CD3- NK-like cells in the thymus. Blood 97 (2001) 1765-1775
    • (2001) Blood , vol.97 , pp. 1765-1775
    • Iwabuchi, K.1    Iwabuchi, C.2    Tone, S.3    Itoh, D.4    Tosa, N.5    Negishi, I.6    Ogasawara, K.7    Uede, T.8    Onoé, K.9
  • 21
    • 0031179646 scopus 로고    scopus 로고
    • IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells
    • Kalinski P., Hilkens C.M., Snijders A., Snijdewint F.G., and Kapsenberg M.L. IL-12-deficient dendritic cells, generated in the presence of prostaglandin E2, promote type 2 cytokine production in maturing human naive T helper cells. J. Immunol. 159 (1997) 28-35
    • (1997) J. Immunol. , vol.159 , pp. 28-35
    • Kalinski, P.1    Hilkens, C.M.2    Snijders, A.3    Snijdewint, F.G.4    Kapsenberg, M.L.5
  • 23
    • 0037245009 scopus 로고    scopus 로고
    • Tumour necrosis factor-α but not lipopolysaccharide enhances preference of murine dendritic cells for Th2 differentiation
    • Kikuchi K., Yanagawa Y., Aranami T., Iwabuchi C., Iwabuchi K., and Onoé K. Tumour necrosis factor-α but not lipopolysaccharide enhances preference of murine dendritic cells for Th2 differentiation. Immunology 108 (2003) 42-49
    • (2003) Immunology , vol.108 , pp. 42-49
    • Kikuchi, K.1    Yanagawa, Y.2    Aranami, T.3    Iwabuchi, C.4    Iwabuchi, K.5    Onoé, K.6
  • 24
    • 10744230081 scopus 로고    scopus 로고
    • Interleukin (IL)-21 and IL-15 genetic transfer synergistically augments therapeutic antitumor immunity and promotes regression of metastatic lymphoma
    • Kishida T., Asada H., Itokawa Y., Cui F.D., Shin-Ya M., Gojo S., Yasutomi K., Ueda Y., Yamagishi H., Imanishi J., and Mazda O. Interleukin (IL)-21 and IL-15 genetic transfer synergistically augments therapeutic antitumor immunity and promotes regression of metastatic lymphoma. Mol. Ther. 8 (2003) 552-558
    • (2003) Mol. Ther. , vol.8 , pp. 552-558
    • Kishida, T.1    Asada, H.2    Itokawa, Y.3    Cui, F.D.4    Shin-Ya, M.5    Gojo, S.6    Yasutomi, K.7    Ueda, Y.8    Yamagishi, H.9    Imanishi, J.10    Mazda, O.11
  • 25
    • 25444434157 scopus 로고    scopus 로고
    • Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation
    • Leonard W.J., and Spolski R. Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation. Nat. Rev. Immunol. 5 (2005) 688-698
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 688-698
    • Leonard, W.J.1    Spolski, R.2
  • 26
    • 0038784488 scopus 로고    scopus 로고
    • IL-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of IFN-γ
    • Ma H.L., Whitters M.J., Konz R.F., Senices M., Young D.A., Grusby M.J., Collins M., and Dunussi-Joannopoulos K. IL-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of IFN-γ. J. Immunol. 171 (2003) 608-615
    • (2003) J. Immunol. , vol.171 , pp. 608-615
    • Ma, H.L.1    Whitters, M.J.2    Konz, R.F.3    Senices, M.4    Young, D.A.5    Grusby, M.J.6    Collins, M.7    Dunussi-Joannopoulos, K.8
  • 28
    • 0035887907 scopus 로고    scopus 로고
    • Regulation of NKT cells by Ly49: analysis of primary NKT cells and generation of NKT cell line
    • Maeda M., Lohwasser S., Yamamura T., and Takei F. Regulation of NKT cells by Ly49: analysis of primary NKT cells and generation of NKT cell line. J. Immunol. 167 (2001) 4180-4186
    • (2001) J. Immunol. , vol.167 , pp. 4180-4186
    • Maeda, M.1    Lohwasser, S.2    Yamamura, T.3    Takei, F.4
  • 29
    • 0035668614 scopus 로고    scopus 로고
    • Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization
    • Mazzoni A., Young H.A., Spitzer J.H., Visintin A., and Segal D.M. Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization. J. Clin. Invest. 108 (2001) 1865-1873
    • (2001) J. Clin. Invest. , vol.108 , pp. 1865-1873
    • Mazzoni, A.1    Young, H.A.2    Spitzer, J.H.3    Visintin, A.4    Segal, D.M.5
  • 30
  • 31
    • 23944522338 scopus 로고    scopus 로고
    • Negative feedback regulation of T helper type 1 (Th1)/Th2 cytokine balance via dendritic cell and natural killer T cell interactions
    • Minami K., Yanagawa Y., Iwabuchi K., Shinohara N., Harabayashi T., Nonomura K., and Onoé K. Negative feedback regulation of T helper type 1 (Th1)/Th2 cytokine balance via dendritic cell and natural killer T cell interactions. Blood 106 (2005) 1685-1693
    • (2005) Blood , vol.106 , pp. 1685-1693
    • Minami, K.1    Yanagawa, Y.2    Iwabuchi, K.3    Shinohara, N.4    Harabayashi, T.5    Nonomura, K.6    Onoé, K.7
  • 32
    • 0035807302 scopus 로고    scopus 로고
    • A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells
    • Miyamoto K., Miyake S., and Yamamura T. A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 413 (2001) 531-534
    • (2001) Nature , vol.413 , pp. 531-534
    • Miyamoto, K.1    Miyake, S.2    Yamamura, T.3
  • 33
    • 2542595794 scopus 로고    scopus 로고
    • IL-21 enhances and sustains CD8+ T cell responses to achieve durable tumor immunity: comparative evaluation of IL-2, IL-15, and IL-21
    • Moroz A., Eppolito C., Li Q., Tao J., Clegg C.H., and Shrikant P.A. IL-21 enhances and sustains CD8+ T cell responses to achieve durable tumor immunity: comparative evaluation of IL-2, IL-15, and IL-21. J. Immunol. 173 (2004) 900-909
    • (2004) J. Immunol. , vol.173 , pp. 900-909
    • Moroz, A.1    Eppolito, C.2    Li, Q.3    Tao, J.4    Clegg, C.H.5    Shrikant, P.A.6
  • 35
    • 0034606290 scopus 로고    scopus 로고
    • Fas engagement induces the maturation of dendritic cells (DCs), the release of interleukin (IL) -1â, and the production of interferon ã in the absence of IL-12 during DC-T cell cognate interaction: a new role for Fas ligand in inflammatory responses
    • Rescigno M., Piguet V., Valzasina B., Lens S., Zubler R., French L., Kindler V., Tschopp J., and Ricciardi-Castagnoli P. Fas engagement induces the maturation of dendritic cells (DCs), the release of interleukin (IL) -1â, and the production of interferon ã in the absence of IL-12 during DC-T cell cognate interaction: a new role for Fas ligand in inflammatory responses. J. Exp. Med. 192 (2000) 1661-1668
    • (2000) J. Exp. Med. , vol.192 , pp. 1661-1668
    • Rescigno, M.1    Piguet, V.2    Valzasina, B.3    Lens, S.4    Zubler, R.5    French, L.6    Kindler, V.7    Tschopp, J.8    Ricciardi-Castagnoli, P.9
  • 39
    • 0033198183 scopus 로고    scopus 로고
    • Activation of NK T cells by CD1d and α-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype
    • Singh N., Hong S., Scherer D.C., Serizawa I., Burdin N., Kronenberg M., Koezuka Y., and Kaer L.V. Activation of NK T cells by CD1d and α-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype. J. Immunol. 163 (1999) 2373-2377
    • (1999) J. Immunol. , vol.163 , pp. 2373-2377
    • Singh, N.1    Hong, S.2    Scherer, D.C.3    Serizawa, I.4    Burdin, N.5    Kronenberg, M.6    Koezuka, Y.7    Kaer, L.V.8
  • 40
    • 0035911242 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon γ-dependent natural killer cell protection from tumor metastasis
    • Smyth M.J., Cretney E., Takeda K., Wiltrout R.H., Sedger L.M., Kayagaki N., Yagita H., and Okumura K. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon γ-dependent natural killer cell protection from tumor metastasis. J. Exp. Med. 193 (2001) 661-670
    • (2001) J. Exp. Med. , vol.193 , pp. 661-670
    • Smyth, M.J.1    Cretney, E.2    Takeda, K.3    Wiltrout, R.H.4    Sedger, L.M.5    Kayagaki, N.6    Yagita, H.7    Okumura, K.8
  • 41
    • 0037082487 scopus 로고    scopus 로고
    • Sequential production of interferon-γ by NK1.1+ T cells and natural killer cells is essential for the antimetastatic effect of α-galactosylceramide
    • Smyth M.J., Crowe N.Y., Pellicci D.G., Kyparissoudis K., Kelly J.M., Takeda K., Yagita H., and Godfrey D.I. Sequential production of interferon-γ by NK1.1+ T cells and natural killer cells is essential for the antimetastatic effect of α-galactosylceramide. Blood 99 (2002) 1259-1266
    • (2002) Blood , vol.99 , pp. 1259-1266
    • Smyth, M.J.1    Crowe, N.Y.2    Pellicci, D.G.3    Kyparissoudis, K.4    Kelly, J.M.5    Takeda, K.6    Yagita, H.7    Godfrey, D.I.8
  • 42
    • 22344451592 scopus 로고    scopus 로고
    • Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer
    • Smyth M.J., Wallace M.E., Nutt S.L., Yagita H., Godfrey D.I., and Hayakawa Y. Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer. J. Exp. Med. 201 (2005) 1973-1985
    • (2005) J. Exp. Med. , vol.201 , pp. 1973-1985
    • Smyth, M.J.1    Wallace, M.E.2    Nutt, S.L.3    Yagita, H.4    Godfrey, D.I.5    Hayakawa, Y.6
  • 43
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • Steinman R.M. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 9 (1991) 271-296
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 271-296
    • Steinman, R.M.1
  • 45
    • 0038228956 scopus 로고    scopus 로고
    • The regulatory role of Vα14 NKT cells in innate and acquired immune response
    • Taniguchi M., Harada M., Kojo S., Nakayama T., and Wakao H. The regulatory role of Vα14 NKT cells in innate and acquired immune response. Annu. Rev. Immunol. 21 (2003) 483-513
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 483-513
    • Taniguchi, M.1    Harada, M.2    Kojo, S.3    Nakayama, T.4    Wakao, H.5
  • 46
    • 0037347311 scopus 로고    scopus 로고
    • Expression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hosts
    • Ugai S., Shimozato O., Kawamura K., Wang Y.Q., Yamaguchi T., Saisho H., Sakiyama S., and Tagawa M. Expression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hosts. Cancer Gene Ther. 10 (2003) 187-192
    • (2003) Cancer Gene Ther. , vol.10 , pp. 187-192
    • Ugai, S.1    Shimozato, O.2    Kawamura, K.3    Wang, Y.Q.4    Yamaguchi, T.5    Saisho, H.6    Sakiyama, S.7    Tagawa, M.8
  • 49
    • 0036256943 scopus 로고    scopus 로고
    • Immunotherapy with ligands of natural killer T cells
    • Wilson M.T., Singh A.K., and Van Kaer L. Immunotherapy with ligands of natural killer T cells. Trends Mol. Med. 8 (2002) 225-231
    • (2002) Trends Mol. Med. , vol.8 , pp. 225-231
    • Wilson, M.T.1    Singh, A.K.2    Van Kaer, L.3
  • 51
    • 0037037544 scopus 로고    scopus 로고
    • Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon γ-producing Th1 cells
    • Wurster A.L., Rodgers V.L., Satoskar A.R., Whitters M.J., Young D.A., Collins M., and Grusby M.J. Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon γ-producing Th1 cells. J. Exp. Med. 196 (2002) 969-977
    • (2002) J. Exp. Med. , vol.196 , pp. 969-977
    • Wurster, A.L.1    Rodgers, V.L.2    Satoskar, A.R.3    Whitters, M.J.4    Young, D.A.5    Collins, M.6    Grusby, M.J.7
  • 52
    • 0042512461 scopus 로고    scopus 로고
    • Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells
    • Yamazaki S., Iyoda T., Tarbell K., Olson K., Velinzon K., Inaba K., and Steinman R.M. Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J. Exp. Med. 198 (2003) 235-247
    • (2003) J. Exp. Med. , vol.198 , pp. 235-247
    • Yamazaki, S.1    Iyoda, T.2    Tarbell, K.3    Olson, K.4    Velinzon, K.5    Inaba, K.6    Steinman, R.M.7
  • 53
    • 0037105462 scopus 로고    scopus 로고
    • CCL19 induces rapid dendritic extension of murine dendritic cells
    • Yanagawa Y., and Onoé K. CCL19 induces rapid dendritic extension of murine dendritic cells. Blood 100 (2002) 1948-1956
    • (2002) Blood , vol.100 , pp. 1948-1956
    • Yanagawa, Y.1    Onoé, K.2
  • 54
    • 0037707281 scopus 로고    scopus 로고
    • CCR7 ligands induce rapid endocytosis in mature dendritic cells with concomitant up-regulation of Cdc42 and Rac activities
    • Yanagawa Y., and Onoé K. CCR7 ligands induce rapid endocytosis in mature dendritic cells with concomitant up-regulation of Cdc42 and Rac activities. Blood 101 (2003) 4923-4929
    • (2003) Blood , vol.101 , pp. 4923-4929
    • Yanagawa, Y.1    Onoé, K.2
  • 55
    • 33645017942 scopus 로고    scopus 로고
    • Distinct regulation of CD40-mediated interleukin-6 and interleukin-12 productions via mitogen-activated protein kinase and nuclear factor κB-inducing kinase in mature dendritic cells
    • Yanagawa Y., and Onoé K. Distinct regulation of CD40-mediated interleukin-6 and interleukin-12 productions via mitogen-activated protein kinase and nuclear factor κB-inducing kinase in mature dendritic cells. Immunology 117 (2006) 526-535
    • (2006) Immunology , vol.117 , pp. 526-535
    • Yanagawa, Y.1    Onoé, K.2
  • 56
    • 0036141344 scopus 로고    scopus 로고
    • Activation of extracellular signal-related kinase by TNF-α controls the maturation and function of murine dendritic cells
    • Yanagawa Y., Iijima N., Iwabuchi K., and Onoé K. Activation of extracellular signal-related kinase by TNF-α controls the maturation and function of murine dendritic cells. J. Leukoc. Biol. 71 (2002) 125-132
    • (2002) J. Leukoc. Biol. , vol.71 , pp. 125-132
    • Yanagawa, Y.1    Iijima, N.2    Iwabuchi, K.3    Onoé, K.4


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