Varenicline (Chantix) for smoking cessation

American Family Physician

Volumn 76, Issue 2, 2007, Pages 279-

  Love, Bryan L ^a   Merz, Tonja ^a  

^a WINGATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; NICOTINE; NICOTINIC RECEPTOR; PLACEBO; VARENICLINE;

ABNORMAL DREAMING; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; FLATULENCE; HEADACHE; HUMAN; INSOMNIA; NAUSEA; REVIEW; SMOKING; SMOKING CESSATION; STIMULATION; THEORY; WITHDRAWAL SYNDROME;

EID: 34547143760     PISSN: 0002838X     EISSN: 0002838X     Source Type: Journal    
DOI: None     Document Type: Review

References (8)

1. Coe JW, Brooks PR, Vetelino MG, Wirtz MC, Arnold EP, Huang J, et al. Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation. J Med Chem 2005;48:3474-7.
2. Chantix (varenicline) tablets [Prescribing information]. New York, N.Y.: Pfizer Labs, 2006. Accessed April 17, 2007, at: http://www.pfizer.com/pfizer/ download/uspi_chantix.pdf.
3. Oncken C, Gonzales D, Nides M, Rennard S, Watsky E, Billing CB, et al. Efficacy and safety of the novel selective nicotinic acetylcholine receptor partial agonist, varenicline, for smoking cessation. Arch Intern Med 2006;166:1571-7.
4. Tonstad S, Tonnesen P, Hajek P, Williams KE, Billing CB, Reeves KR, for the Varenicline Phase 3 Study Group. Effect of maintenance therapy with varenicline on smoking cessation: a randomized controlled trial. JAMA 2006;296:64-71.
5. Gonzales D, Rennard SI, Nides M, Oncken C, Azoulay S, Billing CB, et al., for the Varenicline Phase 3 Study Group. Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs. sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial. JAMA 2006;296:47-55.
6. Jorenby DE, Hays JT, Rigotti NA, Azoulay SA, Watsky EJ, Williams KE, et al., for the Varenicline Phase 3 Study Group. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs. placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial [Published correction appears in JAMA 2006;296:1355]. JAMA 2006;296:56-63.
7. Nides M, Oncken C, Gonzales D, Rennard S, Watsky EJ, Anziano R, et al. Smoking cessation with varenicline, a selective alpha4beta2 nicotinic receptor partial agonist: results from a 7-week, randomized, placebo- and bupropion-controlled trial with 1-year follow-up. Arch Intern Med 2006;166:1561-8.
8. Campaign for Tobacco-Free Kids. State cigarette prices, taxes, and costs per pack. Accessed April 17, 2007, at: http://www.tobaccofreekids.org/research/ factsheets/pdf/0207.pdf.