Identification and characterization of an anomalous racemate

Fluid Phase Equilibria

Volumn 258, Issue 2, 2007, Pages 140-147

  Tabora, J E ^a   Corry, J ^a   Osifchin, R ^a   Lepore, J V ^a   Davidson, O A ^a   Thien, M P ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Addition compound; Anomalous racemate; Crystallization; Enantiomer; Prigogine Defay equation

Indexed keywords

CRYSTALLIZATION; NUMERICAL METHODS; SOLVENTS; STOICHIOMETRY;

ADDITION COMPOUND; ANOMALOUS RACEMATE; BUTANOIC ACID; PRIGOGINE-DEFAY EQUATION;

ENANTIOMERS;

CRYSTALLIZATION; ENANTIOMERS; NUMERICAL METHODS; SOLVENTS; STOICHIOMETRY;

EID: 34547131321     PISSN: 03783812     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fluid.2007.05.008     Document Type: Article

References (21)

1. Strong M. FDA policy and regulation of stereoisomers: paradigm shift and the future of safer, more effective drugs. Food Drug Law J. 54 (1999) 463
2. Kraushaar K.J. Market exclusivity after a prescription to nonprescription drug switch: striking the right balance between innovation and competition. Food Drug J. 54 (2000) 243-244
3. Hindmarch I. The enantiomer debate: current status and future directions 16. Hum. Psychopharmacol. Clin. Exp. 16 (2001) S101-S104
4. Pifferi G., and Perucca E. The cost benefit ratio of enantiomeric drugs. Eur. J. Drug Metab. Pharmacokinet. 20 (1995) 15-25
5. De Camp W.H. Chiral drugs: the FDA perspective on manufacturing and control. J. Pharmaceut. Biomed. Anal. 11 (1993) 1167-1172
6. Beck G. Synthesis of chiral drug substances. Synlett 6 (2002) 837-850
7. Schaus J.V. The emergence of chiral drugs. C.&En.News 78 (2000) 55-78
8. Rouhi A.M. Chiral chemistry. C.&En.News 81 (2003) 45
9. Schroer J.E., Wibowo C., and Ng K.N. Synthesis of chiral crystallization processes. AIChE J. 47 (2001) 387
10. Collet A. Separation and purification of enantiomers by crystallisation [sic] methods. Enantiomer 4 (1999) 157
11. Jacques J., Collet A., and Wilen S.H. Enantiomers Racemates and Resolutions (1994), Krieger Publishing Company, Florida
12. Flack H.D. Chiral achiral crystal structures. Helv. Chim. Acta 86 (2003) 905
13. Prigogine I., and Defay R. Chemical Thermodynamics (1962), John Wiley & Sons Inc., New York (Translated by D.H. Everett)
14. Bergmann M., and Lissitzin M. Die überzähligen steroisomeren der γ-amino-β-oxy-buttersäure. Ber. Dtsch. Chem. Ges. 63 (1930) 310-313
15. Andersson M., and Fredga A. Anomalous racemates of malic acid. Acta Chem. Scand. 20 (1966) 1060-1061
16. Toke L., Ács M., Fogassy E., Faighl F., Gál S., and Sztatisz J. A new anomalous racemate. Acta Chim. Acad. Sci. Hung. 102 (1979) 59
17. 3CO. Chem. Commun. (1969) 899
18. Gallis H., van Ekeren P.J., van Miltenburg J.C., and Oonk H.A.J. Mixtures of d- and l-carvone. IV. Transformation from a solid solution to a racemic compound. Thermochim. Acta 326 (1999) 83
19. Cox P.J., Jaspars M., Kumarasamy Y., Nahar L., and Sarker A.D. An anomalous racemate of naringenin at 120 K. Acta Crystallogr. Section E 59 (2003) 46
20. In: Kozma D. (Ed). CRC Hanbook of Optical Resolution via Diastereomeric Salt Formation (2001), CRC Press
21. Ács M., Kozma D., and Fogassy E. Enantiomer separation via diastereoisomeric salt formation by liquid-liquid phase transition. ACH Models Chem. 132 (1995) 475-479