Systematic analysis of the entire second extracellular loop of the V 1a vasopressin receptor: Key residues, conserved throughout a G-protein-coupled receptor family, identified

Journal of Biological Chemistry

Volumn 282, Issue 24, 2007, Pages 17405-17412

  Conner, Matthew ^a   Hawtin, Stuart R ^a,b   Simms, John ^a,c   Wootten, Denise ^a   Lawson, Zoe ^a   Conner, Alex C ^a,d   Parslow, Rosemary A ^a   Wheatley, Mark ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b NOVARTIS PHARMA AG   (Switzerland)

^c MONASH UNIVERSITY   (Australia)

^d SWANSEA UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BINDING SITES; CELL MEMBRANES; HORMONES; LIGANDS; SUBSTITUTION REACTIONS;

EXTRACELLULAR LOOP; TRANSMEMBRANE; VASOPRESSIN RECEPTORS; X RAY STRUCTURE;

PROTEINS;

ALANINE; CYSTINE; G PROTEIN COUPLED RECEPTOR; MUTANT PROTEIN; NEUROHYPOPHYSIS HORMONE; PHENYLALANINE; TRYPTOPHAN; TYROSINE; VASOPRESSIN V1A RECEPTOR;

AGONIST; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DISULFIDE BOND; EMBRYO; HUMAN; HUMAN CELL; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; RAT; SIGNAL TRANSDUCTION; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; CELL LINE; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, VASOPRESSIN; SEQUENCE ALIGNMENT;

BOVINAE;

EID: 34547130064     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M702151200     Document Type: Article

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