The toxic origins of disease

PLoS Biology

Volumn 5, Issue 7, 2007, Pages 1392-1398

  Gross, Liza ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; DIETHYLSTILBESTROL; ENDOCRINE DISRUPTOR; ESTROGEN; PESTICIDE; PLASTIC; POLYCARBONATE; PHENOL DERIVATIVE;

CHEMICAL INDUSTRY; CHROMOSOME; DISEASE ASSOCIATION; EMBRYO DEVELOPMENT; ENDOCRINE SYSTEM; ENVIRONMENTAL HEALTH; EXPERIMENTAL STUDY; GENITAL SYSTEM; HEALTH HAZARD; HORMONE DETERMINATION; HUMAN; MEDICAL RESEARCH; MOLECULAR BIOLOGY; OBESITY; OOCYTE DEVELOPMENT; PREGNANT WOMAN; REPRODUCTIVE TOXICITY; REVIEW; TOXICOLOGY; WEIGHT GAIN; ANIMAL; ARTICLE; DRUG EFFECT; FEMALE; HISTORY; MALE; MALE GENITAL SYSTEM; PREGNANCY; PRENATAL EXPOSURE; RISK ASSESSMENT; UNITED STATES;

ANIMALS; ENDOCRINE DISRUPTORS; ESTROGENS, NON-STEROIDAL; FEMALE; GENITALIA, MALE; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; MALE; OBESITY; PHENOLS; PLASTICS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RISK ASSESSMENT; UNITED STATES;

EID: 34547122256     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0050193     Document Type: Review

References (22)

1. vom Saal FS, Timms BG, Montano MM, Palanza P, Thayer KA, et al. (1997) Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at low doses. Proc Natl Acad Sci U S A 94: 2056-2061
2. Nagel SC, vom Saal FS, Thayer KA, Dhar MG, Boechler M, et al. (1997) Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo bioactivity of the xenoestrogens bisphenol A and octylphenol. EnvironHealth Perspect 105: 70-76.
3. vom Saal FS, Cooke PS, Buchanan DL, Palanza P, Thayer KA, et al. (1998) A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior. Toxicol Indust Health 14: 239-260.
4. Ashby J (1999) Endocrine disruption: Lessons learned. Environ Health Perspect 107: A488-A489.
5. Ashby J, Tinwell H, Haseman J (1999) Lack of effects for low dose levels of bisphenol A and diethylstilbestrol on the prostate gland of CF1 mice exposed in utero. Regul Toxicol Pharmacol 30: 156-66.
6. Ashby J, Odum J, Paton D, Lefevre PA, Beresford N, et al. (2000) Re-evaluation of the first synthetic estrogen, 1-keto-1,2,3, 4-tetrahydrophenanthrene, and bisphenol A, using both the ovariectomised rat model used in 1933 and additional assays. Toxicol Lett 115: 231-238.
7. Tinwell H, Joiner R, Pate I, Soames A, Foster J, Ashby J (2000) Uterotrophic activity of bisphenol A in the immature mouse. Regul Toxicol Pharmacol 32: 118-126.
8. Ashby J (2000) Validation of in vitro and in vivo methods for assessing endocrine disrupting chemicals. Toxicol Pathol 28: 432-7.
9. Cagen SZ, Waechter Jr JM, Dimond SS, Breslin WJ, Butala JH (1999) Normal reproductive organ development in CF-1 mice following prenatal exposure to bisphenol A. Toxicol Sci 50: 36-44.
10. Gupta C (1999) Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals. Proc Soc Exp Biol Med 224: 61-68.
11. Timms BG, Howdeshell KL, Barton L, Bradley S, Richter CA (2005) Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra. Proc Natl Acad Sci U S A 102: 7014-7019
12. Elswick BA, Miller FJ, Welsch F (2001) Comments to the editor concerning the paper entitled "Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals" by C. Gupta. Proc Soc Exp Biol Med 226: 74-75.
13. Gupta C (2001) Response to the letter by B. Elswick et al. from the Chemical Industry Institute of Toxicology. Proc Soc Exp Biol Med 226: 76-77.
14. NTP (2001) National Toxicology Program's report of the endocrine disruptors low dose peer review. Research Triangle Park (North Carolina): National Toxicology Program. Available: http://ntp.niehs.nih.gov/index.cfm? objectid=06F5CE98-E82F-8182-7FA81C02D3690D47. Accessed 24 May 2007.
15. Gray GM, Cohen JT, Cunha G, Hughes C, McConnell EE (2004) Weight of the evidence evaluation of low-dose reproductive and developmental effects of bisphenol A. Hum Ecol Risk Assess 10: 875-921.
16. vom Saal FS, Hughes C (2005) An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment.. Environ Health Perspect 113: 926-933.
17. Goodman JE, McConnel EE, Sipes IG, Witorsch RJ, Slayton TM, et al. (2006) An updated weight of the evidence evaluation of reproductive and developmental effects of low doses of bisphenol A. Crit Rev Toxicol 36: 387-457.
18. Hunt PA, Koehler KE, Susiarjo M, Hodges CA, Ilagan A, et al. (2003) Bisphenol A exposure causes meiotic aneuploidy in the female mouse. Curr Biol 13: 546-53.
19. Susiarjo M, Hasold TJ, Freeman E, Hunt PA (2007) Bisphenol A exposure in utero disrupts early oogenesis in the mouse. PLoS Genetics 3(1): e5. doi:10.1371/journal.pgen.0030005.
20. Calafat AM, Kuklenyik Z, Reidy JA, Caudill SP, Ekong J, et al. (2005) Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population. Environ Health Perspect 113: 391-395.
21. Baillie-Hamilton PF (2002) Chemical toxins: A hypothesis to explain the global obesity epidemic. J Alt Comp Med 8: 185-192.
22. Grun F, Blumberg B (2006) Environmental obesogens: Organotins and endocrine disruption via nuclear receptor signaling. Endocrinology 147: s50-s55.