Cell cannibalism and nucleus-fragmented cells in voided urine: Useful parameters for cytologic diagnosis of low-grade urothelial carcinoma

Acta Cytologica

Volumn 51, Issue 4, 2007, Pages 547-551

  Hattori, Manabu ^a   Nishino, Yuki ^a   Kakinuma, Hirokuni ^b   Matsumoto, Kazumasa ^a   Ohbu, Makoto ^a   Okayasu, Isao ^a  

^a KITASATO UNIVERSITY   (Japan)

^b KITASATO UNIVERSITY HOSPITAL   (Japan)

Author keywords

Carcinoma, urothelial; Cell cannibalism; Cell, nucleus fragmented; Cytology; Urine

Indexed keywords

ADULT; AGED; ARTICLE; CANCER CYTODIAGNOSIS; CANCER GRADING; CELL CANNIBALISM; CELL KILLING; CELL TYPE; CLINICAL ARTICLE; DIAGNOSTIC ACCURACY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; NUCLEUS FRAGMENTED CELL; PRIORITY JOURNAL; URINALYSIS; URINARY TRACT CANCER; UROTHELIUM; UROTHELIUM CANCER;

EID: 34547118559     PISSN: 00015547     EISSN: 19382650     Source Type: Journal    
DOI: 10.1159/000325792     Document Type: Article

References (17)

1. Koss LG, Deitch D, Ramanathan R, Sherman AB: Diagnostic value of cytology of voided urine. Acta Cytol 1985;29:810-816
2. Matzkin H, Moinuddin SM, Soloway MS: Value of urine cytology versus bladder washing in bladder cancer. Urology 1992;39:201-203
3. Zein TA, Milad MF: Urine cytology in bladder tumors. Int Surg 1991;76:52-54
4. Bauchwitz MA: The "bird eye cell": Cannibalism or abnormal division of tumor cells? Acta Cytol 1981;25:92
5. Shimauchi K, Nishi K, Fujii T: Cytology of Urological Diseases (Shin Saiboushin no Susumekata). Edited by K Nishi, Tokyo, Kindai Shuppan, 1990, p 36 (in Japanese)
6. Goldstein ML, Whitman T, Renshaw AA: Significance of cell groups in voided urine. Acta Cytol 1998;42:290-294
7. Suprun H, Bitterman W: A correlative cytohistologic study on the interrelationship between exfoliated urinary bladder carcinoma cell types and the staging and grading of these tumors. Acta Cytol 1975;19:265-273
8. Uei Y, Watanabe Y, Hirota T, Yamamoto H, Watanabe H: Cytologic diagnosis of breast carcinoma with nipple discharge: Special significance of the spherical cell cluster. Acta Cytol 1980;24:522-528
9. Craig ID, Desrosiers P, Lefcoe MS: Giant-cell carcinoma of the lung: A cytologic study. Acta Cytol 1983;27:293-298
10. Hong IS: The exfoliative cytology of endometrial stromal sarcoma in peritoneal fluid. Acta Cytol 1981;25:277-281
11. DeSimone PA, East R, Powell RD Jr: Phagocytic tumor cell activity in oat cell carcinoma of the lung. Hum Pathol 1980;11:535-539
12. Gupta RK, Wakefield SJ: Needle aspiration cytology, immunocytochemistry, and electron microscopic study of unusual pancreatic carcinoma with pleomorphic giant cells. Diagn Cytopathol 1992;8:522-527
13. Gupta K, Dey P: Cell cannibalism: Diagnostic marker of malignancy. Diagn Cytopathol 2003;28:86-87
14. Kojima S, Sekine H, Fukui I, Ohshima H: Clinical significance of "cannibalism" in urinary cytology of bladder cancer. Acta Cytol 1998;42:1365-1369
15. Kinjo M, Soejima T, Watanabe S, Hamano K. Sagiyama K: A cytological and clinical significance of "pair cells" in urine cytology. J Jpn Soc Clin Cytol 1999:38:129-135 (in Japanese with an English abstract)
16. Kinjo M, Soejima T, Watanabe S, Hamano K, Sagiyama K: Morphogenesis of "pair cells" in voided urine cytology: Cytological, pathological and immunocytochemical studies. J Jpn Soc Clin Cytol 1999;38:221-225 (in Japanese with an English abstract)
17. King ED, Matteson J, Jacobs SC, Kyprianou N: Incidence of apoptosis, cell proliferation and bcl-2 expression in transitional cell carcinoma of the bladder: Association with tumor progression. J Urol 1996;155:316-320