2′,5,7-Trihydroxy-4′,5′-(2,2-dimethylchromeno)- 8-(3-hydroxy-3-methylbutyl) flavanone purified from Cudrania tricuspidata induces apoptotic cell death of human leukemia U937 cells

Natural Product Research

Volumn 21, Issue 7, 2007, Pages 616-624

  Rho, Yoon Hwa ^a   Yoon, Soo Hyun ^a   Kim, Eun Kyung ^a   Kang, Ji Young ^a   Lee, Byong Won ^b   Park, Ki Hun ^b   Bae, Young Seuk ^a  

^a Kyungpook National University   (South Korea)

^b Gyeongsang National University   (South Korea)

Author keywords

Anti tumor drug; Apoptosis; Cudrania tricuspidata; DNA topoisomerase I inhibitor; Human leukemia cells

Indexed keywords

2',5,7 TRIHYDROXY 4',5' (2,2 DIMETHYLCHROMENO) 8 (3 HYDROXY 3 METHYLBUTYL)FLAVANONE; CELL DNA; CHLOROFORM; DNA FRAGMENT; DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; HERBACEOUS AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROCASPASE 3; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; FLAVONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BARK; CANCER INHIBITION; CELL STRAIN U937; CONCENTRATION RESPONSE; CONTROLLED STUDY; CUDRANIA TRICUSPIDATA; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; MAMMAL; NONHUMAN; PLANT ROOT; PROTEIN DEGRADATION; PROTEIN SYNTHESIS INHIBITION; SHRUB; STRUCTURE ANALYSIS; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; DRUG SCREENING; INFRARED SPECTROSCOPY; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; MEDICINAL PLANT; METABOLISM; MORACEAE; NUCLEAR MAGNETIC RESONANCE; ULTRAVIOLET SPECTROPHOTOMETRY;

MACLURA TRICUSPIDATA; MAMMALIA;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL SURVIVAL; DNA TOPOISOMERASES, TYPE I; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; FLAVONES; FLOW CYTOMETRY; HUMANS; MASS SPECTROMETRY; MORACEAE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PLANT ROOTS; PLANTS, MEDICINAL; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; U937 CELLS;

EID: 34547113073     PISSN: 14786419     EISSN: 14786427     Source Type: Journal    
DOI: 10.1080/14786410701371041     Document Type: Article

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