-
1
-
-
0027303686
-
Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv
-
Adams, G. P., J. E. McCartney, M. S. Tai, H. Oppermann, J. S. Huston, W. F. Stafford III, M. A. Bookman, I. Fand, L. L. Houston, and L. M. Weiner. 1993. Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv. Cancer Res. 53:4026-4034.
-
(1993)
Cancer Res
, vol.53
, pp. 4026-4034
-
-
Adams, G.P.1
McCartney, J.E.2
Tai, M.S.3
Oppermann, H.4
Huston, J.S.5
Stafford III, W.F.6
Bookman, M.A.7
Fand, I.8
Houston, L.L.9
Weiner, L.M.10
-
2
-
-
0025838021
-
Assembly of combinatorial antibody libraries on phage surfaces: The gene III site
-
Barbas, C. F., III, A. S. Kang, R. A. Lerner, and S. J. Benkovic. 1991. Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Proc. Natl. Acad. Sci. USA 88:7978-7982.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7978-7982
-
-
Barbas III, C.F.1
Kang, A.S.2
Lerner, R.A.3
Benkovic, S.J.4
-
3
-
-
24944533131
-
Effective lysis of lymphoma cells with a stabilised bispecific single-chain Fv antibody against CD19 and FcgammaRIII (CD16)
-
Bruenke, J., K. Barbin, S. Kunert, P. Lang, M. Pfeiffer, K. Stieglmaier, D. Niethammer, B. Stockmeyer, M. Peipp, R. Repp, T. Valerius, and G. H. Fey. 2005. Effective lysis of lymphoma cells with a stabilised bispecific single-chain Fv antibody against CD19 and FcgammaRIII (CD16). Br. J. Haematol. 130:218-228.
-
(2005)
Br. J. Haematol
, vol.130
, pp. 218-228
-
-
Bruenke, J.1
Barbin, K.2
Kunert, S.3
Lang, P.4
Pfeiffer, M.5
Stieglmaier, K.6
Niethammer, D.7
Stockmeyer, B.8
Peipp, M.9
Repp, R.10
Valerius, T.11
Fey, G.H.12
-
4
-
-
0026772358
-
Comparative stabilities in vitro and in vivo of a recombinant mouse antibody FvCys fragment and a bisFvCys conjugate
-
Cumber, A. J., E. S. Ward, G. Winter, G. D. Parnell, and E. J. Wawrzynczak. 1992. Comparative stabilities in vitro and in vivo of a recombinant mouse antibody FvCys fragment and a bisFvCys conjugate. J. Immunol. 149:120-126.
-
(1992)
J. Immunol
, vol.149
, pp. 120-126
-
-
Cumber, A.J.1
Ward, E.S.2
Winter, G.3
Parnell, G.D.4
Wawrzynczak, E.J.5
-
5
-
-
0030009282
-
Leucine zipper dimerized bivalent and bispecific scFv antibodies from a semi-synthetic antibody phage display library
-
de Kruif, J., and T. Logtenberg. 1996. Leucine zipper dimerized bivalent and bispecific scFv antibodies from a semi-synthetic antibody phage display library. J. Biol. Chem. 271:7630-7634.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 7630-7634
-
-
de Kruif, J.1
Logtenberg, T.2
-
6
-
-
0031441221
-
Improved tumour targeting by disulfide stabilized diabodies expressed in Pichia pastoris
-
FitzGerald, K., P. Holliger, and G. Winter. 1997. Improved tumour targeting by disulfide stabilized diabodies expressed in Pichia pastoris. Protein Eng. 10:1221-1225.
-
(1997)
Protein Eng
, vol.10
, pp. 1221-1225
-
-
FitzGerald, K.1
Holliger, P.2
Winter, G.3
-
8
-
-
0028302596
-
Efficient tumor cell lysis mediated by a bispecific single chain antibody expressed in Escherichia coli
-
Gruber, M., B. A. Schodin, E. R. Wilson, and D. M. Kranz. 1994. Efficient tumor cell lysis mediated by a bispecific single chain antibody expressed in Escherichia coli. J. Immunol. 152:5368-5374.
-
(1994)
J. Immunol
, vol.152
, pp. 5368-5374
-
-
Gruber, M.1
Schodin, B.A.2
Wilson, E.R.3
Kranz, D.M.4
-
9
-
-
0027197493
-
Diabodies: Small bivalent and bispecific antibody fragments
-
Holliger, P., T. Prospero, and G. Winter. 1993. "Diabodies": small bivalent and bispecific antibody fragments. Proc. Natl. Acad. Sci. USA 90:6444-6448.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6444-6448
-
-
Holliger, P.1
Prospero, T.2
Winter, G.3
-
10
-
-
0028001154
-
Recombinant single-chain Fv fragments carrying C-terminal cysteine residues: Production of bivalent and biotinylated miniantibodies
-
Kipriyanov, S. M., S. Dubel, F. Breitling, R. E. Kontermann, and M. Little. 1994. Recombinant single-chain Fv fragments carrying C-terminal cysteine residues: production of bivalent and biotinylated miniantibodies. Mol. Immunol. 31:1047-1058.
-
(1994)
Mol. Immunol
, vol.31
, pp. 1047-1058
-
-
Kipriyanov, S.M.1
Dubel, S.2
Breitling, F.3
Kontermann, R.E.4
Little, M.5
-
11
-
-
0026567963
-
Formation of a bispecific antibody by the use of leucine zippers
-
Kostelny, S. A., M. S. Cole, and J. Y. Tso. 1992. Formation of a bispecific antibody by the use of leucine zippers. J. Immunol. 148:1547-1553.
-
(1992)
J. Immunol
, vol.148
, pp. 1547-1553
-
-
Kostelny, S.A.1
Cole, M.S.2
Tso, J.Y.3
-
13
-
-
0029148633
-
A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity
-
Mack, M., G. Riethmuller, and P. Kufer. 1995. A small bispecific antibody construct expressed as a functional single-chain molecule with high tumor cell cytotoxicity. Proc. Natl. Acad. Sci. USA 92:7021-7025.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7021-7025
-
-
Mack, M.1
Riethmuller, G.2
Kufer, P.3
-
14
-
-
0025226085
-
Phage antibodies: Filamentous phage displaying antibody variable domains
-
McCafferty, J., A. D. Griffiths, G. Winter, and D. J. Chiswell. 1990. Phage antibodies: filamentous phage displaying antibody variable domains. Nature 348:552-554.
-
(1990)
Nature
, vol.348
, pp. 552-554
-
-
McCafferty, J.1
Griffiths, A.D.2
Winter, G.3
Chiswell, D.J.4
-
15
-
-
0029077481
-
Engineering disulfide-linked single-chain Fv dimers [(sFv′)2] with improved solution and targeting properties: Anti-digoxin 26-10 (sFv′)2 and anti-c-erbB-2 741F8 (sFv′)2 made by protein folding and bonded through C-terminal cysteinyl peptides
-
McCartney, J. E., M. S. Tai, R. M. Hudziak, G. P. Adams, L. M. Weiner, D. Jin, W. F. Stafford III, S. Liu, M. A. Bookman, A. A. Laminet, et al. 1995. Engineering disulfide-linked single-chain Fv dimers [(sFv′)2] with improved solution and targeting properties: anti-digoxin 26-10 (sFv′)2 and anti-c-erbB-2 741F8 (sFv′)2 made by protein folding and bonded through C-terminal cysteinyl peptides. Protein Eng. 8:301-314.
-
(1995)
Protein Eng
, vol.8
, pp. 301-314
-
-
McCartney, J.E.1
Tai, M.S.2
Hudziak, R.M.3
Adams, G.P.4
Weiner, L.M.5
Jin, D.6
Stafford III, W.F.7
Liu, S.8
Bookman, M.A.9
Laminet, A.A.10
-
16
-
-
0028208743
-
Spontaneous assembly of bivalent single chain antibody fragments in Escherichia coli
-
McGregor, D. P., P. E. Molloy, C. Cunningham, and W. J. Harris. 1994. Spontaneous assembly of bivalent single chain antibody fragments in Escherichia coli. Mol. Immunol. 31:219-226.
-
(1994)
Mol. Immunol
, vol.31
, pp. 219-226
-
-
McGregor, D.P.1
Molloy, P.E.2
Cunningham, C.3
Harris, W.J.4
-
17
-
-
0020518331
-
Hybrid hybridomas and their use in immunohistochemistry
-
Milstein, C., and A. C. Cuello. 1983. Hybrid hybridomas and their use in immunohistochemistry. Nature 305:537-540.
-
(1983)
Nature
, vol.305
, pp. 537-540
-
-
Milstein, C.1
Cuello, A.C.2
-
18
-
-
0021767899
-
Use of peptide tagging to detect proteins expressed from cloned genes: Deletion mapping functional domains of Drosophila hsp70
-
Munro, S., and H. R. Pelham. 1984. Use of peptide tagging to detect proteins expressed from cloned genes: deletion mapping functional domains of Drosophila hsp70. EMBO J. 3:3087-3093.
-
(1984)
EMBO J
, vol.3
, pp. 3087-3093
-
-
Munro, S.1
Pelham, H.R.2
-
19
-
-
0028939489
-
Calmodulin as a versatile tag for antibody fragments
-
Neri, D., C. de Lalla, H. Petrul, P. Neri, and G. Winter. 1995. Calmodulin as a versatile tag for antibody fragments. Bio/Technology 13:373-377.
-
(1995)
Bio/Technology
, vol.13
, pp. 373-377
-
-
Neri, D.1
de Lalla, C.2
Petrul, H.3
Neri, P.4
Winter, G.5
-
20
-
-
28944434529
-
Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on MHC class I-negative tumor cells
-
Offner, S., R. Hofmeister, A. Romaniuk, P. Kufer, and P. A. Baeuerle. 2006. Induction of regular cytolytic T cell synapses by bispecific single-chain antibody constructs on MHC class I-negative tumor cells. Mol. Immunol. 43: 763-771.
-
(2006)
Mol. Immunol
, vol.43
, pp. 763-771
-
-
Offner, S.1
Hofmeister, R.2
Romaniuk, A.3
Kufer, P.4
Baeuerle, P.A.5
-
21
-
-
1542698957
-
Cloning immunoglobulin variable domains for expression by the polymerase chain reaction
-
Orlandi, R., D. H. Gussow, P. T. Jones, and G. Winter. 1989. Cloning immunoglobulin variable domains for expression by the polymerase chain reaction. Proc. Natl. Acad. Sci. USA 86:3833-3837.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 3833-3837
-
-
Orlandi, R.1
Gussow, D.H.2
Jones, P.T.3
Winter, G.4
-
22
-
-
0027442660
-
Improved bivalent miniantibodies, with identical avidity as whole antibodies, produced by high cell density fermentation of Escherichia coli
-
Pack, P., M. Kujau, V. Schroeckh, U. Knupfer, R. Wenderoth, D. Riesenberg, and A. Pluckthun. 1993. Improved bivalent miniantibodies, with identical avidity as whole antibodies, produced by high cell density fermentation of Escherichia coli. Bio/Technology 11:1271-1277.
-
(1993)
Bio/Technology
, vol.11
, pp. 1271-1277
-
-
Pack, P.1
Kujau, M.2
Schroeckh, V.3
Knupfer, U.4
Wenderoth, R.5
Riesenberg, D.6
Pluckthun, A.7
-
23
-
-
0026528230
-
Miniantibodies: Use of amphipathic helices to produce functional, flexibly linked dimeric FV fragments with high avidity in Escherichia coli
-
Pack, P., and A. Pluckthun. 1992. Miniantibodies: use of amphipathic helices to produce functional, flexibly linked dimeric FV fragments with high avidity in Escherichia coli. Biochemistry 31:1579-1584.
-
(1992)
Biochemistry
, vol.31
, pp. 1579-1584
-
-
Pack, P.1
Pluckthun, A.2
-
24
-
-
30344458506
-
A multivalent recombinant antibody fragment specific for carcinoembryonic antigen
-
Perez, L., M. Ayala, G. Pimentel, H. Bell, L. Canaan-Haden, M. Bequet, L. J. Gonzalez, M. Miranda, R. Ravelo, L. Roque, B. Acevedo, J. P. Oliva, and J. V. Gavilondo. 2006. A multivalent recombinant antibody fragment specific for carcinoembryonic antigen. Biotechnol. Appl. Biochem. 43:39-48.
-
(2006)
Biotechnol. Appl. Biochem
, vol.43
, pp. 39-48
-
-
Perez, L.1
Ayala, M.2
Pimentel, G.3
Bell, H.4
Canaan-Haden, L.5
Bequet, M.6
Gonzalez, L.J.7
Miranda, M.8
Ravelo, R.9
Roque, L.10
Acevedo, B.11
Oliva, J.P.12
Gavilondo, J.V.13
-
25
-
-
30344441648
-
Anti-CD3 X anti-epidermal growth factor receptor (EGFR) bispecific antibody redirects T-cell cytolytic activity to EGFR-positive cancers in vitro and in an animal model
-
Reusch, U., M. Sundaram, P. A. Davol, S. D. Olson, J. B. Davis, K. Demel, J. Nissim, R. Rathore, P. Y. Liu, and L. G. Lum. 2006. Anti-CD3 X anti-epidermal growth factor receptor (EGFR) bispecific antibody redirects T-cell cytolytic activity to EGFR-positive cancers in vitro and in an animal model. Clin. Cancer Res. 12:183-190.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 183-190
-
-
Reusch, U.1
Sundaram, M.2
Davol, P.A.3
Olson, S.D.4
Davis, J.B.5
Demel, K.6
Nissim, J.7
Rathore, R.8
Liu, P.Y.9
Lum, L.G.10
-
26
-
-
33645007038
-
T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct
-
Schlereth, B., C. Quadt, T. Dreier, P. Kufer, G. Lorenczewski, N. Prang, C. Brandl, S. Lippold, K. Cobb, K. Brasky, E. Leo, R. Bargou, K. Murthy, and P. A. Baeuerle. 2006. T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct. Cancer Immunol. Immunother. 55:503-514.
-
(2006)
Cancer Immunol. Immunother
, vol.55
, pp. 503-514
-
-
Schlereth, B.1
Quadt, C.2
Dreier, T.3
Kufer, P.4
Lorenczewski, G.5
Prang, N.6
Brandl, C.7
Lippold, S.8
Cobb, K.9
Brasky, K.10
Leo, E.11
Bargou, R.12
Murthy, K.13
Baeuerle, P.A.14
-
27
-
-
0026604793
-
Development of humanized bispecific antibodies reactive with cytotoxic lymphocytes and tumor cells overexpressing the HER2 protooncogene
-
Shalaby, M. R., H. M. Shepard, L. Presta, M. L. Rodrigues, P. C. Beverley, M. Feldmann, and P. Carter. 1992. Development of humanized bispecific antibodies reactive with cytotoxic lymphocytes and tumor cells overexpressing the HER2 protooncogene. J. Exp. Med. 175:217-225.
-
(1992)
J. Exp. Med
, vol.175
, pp. 217-225
-
-
Shalaby, M.R.1
Shepard, H.M.2
Presta, L.3
Rodrigues, M.L.4
Beverley, P.C.5
Feldmann, M.6
Carter, P.7
-
28
-
-
0021832361
-
Hybrid antibodies can target sites for attack by T cells
-
Staerz, U. D., O. Kanagawa, and M. J. Bevan. 1985. Hybrid antibodies can target sites for attack by T cells. Nature 314:628-631.
-
(1985)
Nature
, vol.314
, pp. 628-631
-
-
Staerz, U.D.1
Kanagawa, O.2
Bevan, M.J.3
-
29
-
-
0347169967
-
Construction of ScFv expression vector and expression of anti-HBsAg ScFv
-
Wang, Y., Q. Liu, R. Gao, Y. Zhu, B. Hua, Y. Wang, and J. Xu. 1997. Construction of ScFv expression vector and expression of anti-HBsAg ScFv. Chin. J. Microbiol. Immunol. 17:68-71.
-
(1997)
Chin. J. Microbiol. Immunol
, vol.17
, pp. 68-71
-
-
Wang, Y.1
Liu, Q.2
Gao, R.3
Zhu, Y.4
Hua, B.5
Wang, Y.6
Xu, J.7
-
30
-
-
34547125133
-
ScFv against human RBC from phage antibody library
-
Wang, Y., Q. Liu, J. Xu, Q. Li, Y. Chen, L. Wang, and J. Li. 1998. ScFv against human RBC from phage antibody library. Chin. J. Microbiol. Immunol. 18:68-71.
-
(1998)
Chin. J. Microbiol. Immunol
, vol.18
, pp. 68-71
-
-
Wang, Y.1
Liu, Q.2
Xu, J.3
Li, Q.4
Chen, Y.5
Wang, L.6
Li, J.7
|