메뉴 건너뛰기




Volumn 293, Issue 1, 2007, Pages

Sox9-dependent transcriptional regulation of the proprotein convertase furin

Author keywords

ATDC5 cells; Chondrogenesis; Transforming growth factor

Indexed keywords

FURIN; PARATHYROID HORMONE RELATED PROTEIN; SERINE PROTEINASE; TRANSCRIPTION FACTOR SOX5; TRANSCRIPTION FACTOR SOX6; TRANSCRIPTION FACTOR SOX9;

EID: 34547108581     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00349.2006     Document Type: Article
Times cited : (15)

References (70)
  • 1
    • 0033863769 scopus 로고    scopus 로고
    • Differential expressions of BMP family genes during chondrogenic differentiation of mouse ATDC5 cells
    • Akiyama H, Shukunami C, Nakamura T, Hiraki Y. Differential expressions of BMP family genes during chondrogenic differentiation of mouse ATDC5 cells. Cell Struct Funct 25: 195-204, 2000.
    • (2000) Cell Struct Funct , vol.25 , pp. 195-204
    • Akiyama, H.1    Shukunami, C.2    Nakamura, T.3    Hiraki, Y.4
  • 2
    • 0030820931 scopus 로고    scopus 로고
    • Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites
    • Ambrosetti DC, Basilico C, Dailey L. Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites. Mol Cell Biol 17: 6321-6329, 1997.
    • (1997) Mol Cell Biol , vol.17 , pp. 6321-6329
    • Ambrosetti, D.C.1    Basilico, C.2    Dailey, L.3
  • 3
    • 0025338661 scopus 로고
    • A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells
    • Atsumi T, Miwa Y, Kimata K, Ikawa Y. A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells. Cell Differ Dev 30: 109-116, 1990.
    • (1990) Cell Differ Dev , vol.30 , pp. 109-116
    • Atsumi, T.1    Miwa, Y.2    Kimata, K.3    Ikawa, Y.4
  • 4
    • 0028292383 scopus 로고
    • Expression of the dibasic proprotein processing enzyme furin is directed by multiple promoters
    • Ayoubi TA, Creemers JW, Roebroek AJ, Van de Ven WJ. Expression of the dibasic proprotein processing enzyme furin is directed by multiple promoters. J Biol Chem 269: 9298-9303, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 9298-9303
    • Ayoubi, T.A.1    Creemers, J.W.2    Roebroek, A.J.3    Van de Ven, W.J.4
  • 6
    • 0042703900 scopus 로고    scopus 로고
    • Dimerization of SOX9 is required for chondrogenesis, but not for sex determination
    • Bernard P, Tang P, Liu S, Dewing P, Harley VR, Vilain E. Dimerization of SOX9 is required for chondrogenesis, but not for sex determination. Hum Mol Genet 12: 1755-1765, 2003.
    • (2003) Hum Mol Genet , vol.12 , pp. 1755-1765
    • Bernard, P.1    Tang, P.2    Liu, S.3    Dewing, P.4    Harley, V.R.5    Vilain, E.6
  • 8
    • 0035823510 scopus 로고    scopus 로고
    • Cross-talk between the p42/p44 MAP kinase and Smad pathways in transforming growth factor beta 1-induced furin gene transactivation
    • Blanchette F, Rivard N, Rudd P, Grondin F, Attisano L, Dubois CM. Cross-talk between the p42/p44 MAP kinase and Smad pathways in transforming growth factor beta 1-induced furin gene transactivation. J Biol Chem 276: 33986-33994, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 33986-33994
    • Blanchette, F.1    Rivard, N.2    Rudd, P.3    Grondin, F.4    Attisano, L.5    Dubois, C.M.6
  • 9
    • 0032511081 scopus 로고    scopus 로고
    • Chondrocyte-specific enhancer elements in the Col11a2 gene resemble the Col2a1 tissue-specific enhancer
    • Bridgewater LC, Lefebvre V, de Crombrugghe B. Chondrocyte-specific enhancer elements in the Col11a2 gene resemble the Col2a1 tissue-specific enhancer. J Biol Chem 273: 14998-15006, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 14998-15006
    • Bridgewater, L.C.1    Lefebvre, V.2    de Crombrugghe, B.3
  • 11
    • 0033805579 scopus 로고    scopus 로고
    • The PTH/PTHrP receptor in Jansen's metaphyseal chondrodysplasia
    • Calvi LM, Schipani E. The PTH/PTHrP receptor in Jansen's metaphyseal chondrodysplasia. J Endocrinol Invest 23: 545-554, 2000.
    • (2000) J Endocrinol Invest , vol.23 , pp. 545-554
    • Calvi, L.M.1    Schipani, E.2
  • 12
    • 0034711298 scopus 로고    scopus 로고
    • Cameron A, Appel J, Houghten RA, Lindberg I. Polyarginines are potent furin inhibitors. J Biol Chem 275: 36741-36749, 2000.
    • Cameron A, Appel J, Houghten RA, Lindberg I. Polyarginines are potent furin inhibitors. J Biol Chem 275: 36741-36749, 2000.
  • 13
    • 0035135642 scopus 로고    scopus 로고
    • Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development
    • Chung UI, Schipani E, McMahon AP, Kronenberg HM. Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development. J Clin Invest 107: 295-304, 2001.
    • (2001) J Clin Invest , vol.107 , pp. 295-304
    • Chung, U.I.1    Schipani, E.2    McMahon, A.P.3    Kronenberg, H.M.4
  • 14
    • 0033545215 scopus 로고    scopus 로고
    • Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases
    • Constam DB, Robertson EJ. Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases. J Cell Biol 144: 139-149, 1999.
    • (1999) J Cell Biol , vol.144 , pp. 139-149
    • Constam, D.B.1    Robertson, E.J.2
  • 16
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11: 1475-1489, 1983.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 18
    • 0028906190 scopus 로고
    • Processing of transforming growth factor beta 1 precursor by human furin convertase
    • Dubois CM, Laprise MH, Blanchette F, Gentry LE, Leduc R. Processing of transforming growth factor beta 1 precursor by human furin convertase. J Biol Chem 270: 10618-10624, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 10618-10624
    • Dubois, C.M.1    Laprise, M.H.2    Blanchette, F.3    Gentry, L.E.4    Leduc, R.5
  • 20
    • 0037143766 scopus 로고    scopus 로고
    • A nuclear export signal within the high mobility group domain regulates the nucleocytoplasmic translocation of SOX9 during sexual determination
    • Gasca S, Canizares J, De Santa Barbara P, Mejean C, Poulat F, Berta P, Boizet-Bonhoure B. A nuclear export signal within the high mobility group domain regulates the nucleocytoplasmic translocation of SOX9 during sexual determination. Proc Natl Acad Sci USA 99: 11199-11204, 2002.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 11199-11204
    • Gasca, S.1    Canizares, J.2    De Santa Barbara, P.3    Mejean, C.4    Poulat, F.5    Berta, P.6    Boizet-Bonhoure, B.7
  • 21
    • 0026716831 scopus 로고
    • Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160
    • Hallenberger S, Bosch V, Angliker H, Shaw E, Klenk HD, Garten W. Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160. Nature 360: 358-361, 1992.
    • (1992) Nature , vol.360 , pp. 358-361
    • Hallenberger, S.1    Bosch, V.2    Angliker, H.3    Shaw, E.4    Klenk, H.D.5    Garten, W.6
  • 23
    • 4644358680 scopus 로고    scopus 로고
    • Distinct functions of BMP4 and GDF5 in the regulation of chondrogenesis
    • Hatakeyama Y, Tuan RS, Shum L. Distinct functions of BMP4 and GDF5 in the regulation of chondrogenesis. J Cell Biochem 91: 1204-1217, 2004.
    • (2004) J Cell Biochem , vol.91 , pp. 1204-1217
    • Hatakeyama, Y.1    Tuan, R.S.2    Shum, L.3
  • 24
    • 6044240615 scopus 로고    scopus 로고
    • Bmps: Multifunctional regulators of mammalian embryonic development
    • Hogan BL. Bmps: multifunctional regulators of mammalian embryonic development. Harvey Lect 92: 83-98, 1996.
    • (1996) Harvey Lect , vol.92 , pp. 83-98
    • Hogan, B.L.1
  • 25
    • 0141456382 scopus 로고    scopus 로고
    • Mutagenesis study on the zebra fish SOX9 high-mobility group: Comparison of sequence and non-sequence specific HMG domains
    • Hsiao NW, Samuel D, Liu YN, Chen LC, Yang TY, Jayaraman G, Lyu PC. Mutagenesis study on the zebra fish SOX9 high-mobility group: comparison of sequence and non-sequence specific HMG domains. Biochemistry 42: 11183-11193, 2003.
    • (2003) Biochemistry , vol.42 , pp. 11183-11193
    • Hsiao, N.W.1    Samuel, D.2    Liu, Y.N.3    Chen, L.C.4    Yang, T.Y.5    Jayaraman, G.6    Lyu, P.C.7
  • 27
    • 0032927874 scopus 로고    scopus 로고
    • Mechanism of regulatory target selection by the SOX high-mobility-group domain proteins as revealed by comparison of SOX1/2/3 and SOX9
    • Kamachi Y, Cheah KS, Kondoh H. Mechanism of regulatory target selection by the SOX high-mobility-group domain proteins as revealed by comparison of SOX1/2/3 and SOX9. Mol Cell Biol 19: 107-120, 1999.
    • (1999) Mol Cell Biol , vol.19 , pp. 107-120
    • Kamachi, Y.1    Cheah, K.S.2    Kondoh, H.3
  • 30
    • 10944246561 scopus 로고    scopus 로고
    • SOX9-dependent and -independent transcriptional regulation of human cartilage link protein
    • Kou I, Ikegawa S. SOX9-dependent and -independent transcriptional regulation of human cartilage link protein. J Biol Chem 279: 50942-50948, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 50942-50948
    • Kou, I.1    Ikegawa, S.2
  • 33
    • 0030851716 scopus 로고    scopus 로고
    • A unique role of the beta-2 thyroid hormone receptor isoform in negative regulation by thyroid hormone. Mapping of a novel aminoterminal domain important for ligand-independent activation
    • Langlois MF, Zanger K, Monden T, Safer JD, Hollenberg AN, Wondisford FE. A unique role of the beta-2 thyroid hormone receptor isoform in negative regulation by thyroid hormone. Mapping of a novel aminoterminal domain important for ligand-independent activation. J Biol Chem 272: 24927-24933, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 24927-24933
    • Langlois, M.F.1    Zanger, K.2    Monden, T.3    Safer, J.D.4    Hollenberg, A.N.5    Wondisford, F.E.6
  • 34
    • 0037111737 scopus 로고    scopus 로고
    • Furin gene (fur) regulation in differentiating human megakaryoblastic Dami cells: Involvement of the proximal GATA recognition motif in the P1 promoter and impact on the maturation of furin substrates
    • Laprise MH, Grondin F, Cayer P, McDonald PP, Dubois CM. Furin gene (fur) regulation in differentiating human megakaryoblastic Dami cells: involvement of the proximal GATA recognition motif in the P1 promoter and impact on the maturation of furin substrates. Blood 100: 3578-3587, 2002.
    • (2002) Blood , vol.100 , pp. 3578-3587
    • Laprise, M.H.1    Grondin, F.2    Cayer, P.3    McDonald, P.P.4    Dubois, C.M.5
  • 35
    • 0030899814 scopus 로고    scopus 로고
    • SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene
    • Lefebvre V, Huang W, Harley VR, Goodfellow PN, de Crombrugghe B. SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene. Mol Cell Biol 17: 2336-2346, 1997.
    • (1997) Mol Cell Biol , vol.17 , pp. 2336-2346
    • Lefebvre, V.1    Huang, W.2    Harley, V.R.3    Goodfellow, P.N.4    de Crombrugghe, B.5
  • 36
    • 0032189223 scopus 로고    scopus 로고
    • A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene
    • Lefebvre V, Li P, de Crombrugghe B. A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J 17: 5718-5733, 1998.
    • (1998) EMBO J , vol.17 , pp. 5718-5733
    • Lefebvre, V.1    Li, P.2    de Crombrugghe, B.3
  • 37
    • 8944238474 scopus 로고    scopus 로고
    • An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes
    • Lefebvre V, Zhou G, Mukhopadhyay K, Smith CN, Zhang Z, Eberspaecher H, Zhou X, Sinha S, Maity SN, de Crombrugghe B. An 18-base-pair sequence in the mouse proalpha1(II) collagen gene is sufficient for expression in cartilage and binds nuclear proteins that are selectively expressed in chondrocytes. Mol Cell Biol 16: 4512-4523, 1996.
    • (1996) Mol Cell Biol , vol.16 , pp. 4512-4523
    • Lefebvre, V.1    Zhou, G.2    Mukhopadhyay, K.3    Smith, C.N.4    Zhang, Z.5    Eberspaecher, H.6    Zhou, X.7    Sinha, S.8    Maity, S.N.9    de Crombrugghe, B.10
  • 38
    • 0023685731 scopus 로고
    • Embryonic expression pattern of TGF beta type-1 RNA suggests both paracrine and autocrine mechanisms of action
    • Lehnert SA, Akhurst RJ. Embryonic expression pattern of TGF beta type-1 RNA suggests both paracrine and autocrine mechanisms of action. Development 104: 263-273, 1988.
    • (1988) Development , vol.104 , pp. 263-273
    • Lehnert, S.A.1    Akhurst, R.J.2
  • 39
    • 0028829117 scopus 로고
    • Inhibition of processing of parathyroid hormone-related peptide by anti-sense furin: Effect in vitro and in vivo on rat Leydig (H-500) tumor cells
    • Liu B, Amizuka N, Goltzman D, Rabbani SA. Inhibition of processing of parathyroid hormone-related peptide by anti-sense furin: effect in vitro and in vivo on rat Leydig (H-500) tumor cells. Int J Cancer 63: 276-281, 1995.
    • (1995) Int J Cancer , vol.63 , pp. 276-281
    • Liu, B.1    Amizuka, N.2    Goltzman, D.3    Rabbani, S.A.4
  • 40
    • 0033485401 scopus 로고    scopus 로고
    • Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells
    • McDonald PP, Fadok VA, Bratton D, Henson PM. Transcriptional and translational regulation of inflammatory mediator production by endogenous TGF-beta in macrophages that have ingested apoptotic cells. J Immunol 163: 6164-6172, 1999.
    • (1999) J Immunol , vol.163 , pp. 6164-6172
    • McDonald, P.P.1    Fadok, V.A.2    Bratton, D.3    Henson, P.M.4
  • 41
    • 14844299760 scopus 로고    scopus 로고
    • Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1: Impact on the bioactivation of proproteins
    • McMahon S, Grondin F, McDonald PP, Richard DE, Dubois CM. Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1: impact on the bioactivation of proproteins. J Biol Chem 280: 6561-6569, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 6561-6569
    • McMahon, S.1    Grondin, F.2    McDonald, P.P.3    Richard, D.E.4    Dubois, C.M.5
  • 42
    • 0033105051 scopus 로고    scopus 로고
    • The DNA-binding specificity of SOX9 and other SOX proteins
    • Mertin S, McDowall SG, Harley VR. The DNA-binding specificity of SOX9 and other SOX proteins. Nucleic Acids Res 27: 1359-1364, 1999.
    • (1999) Nucleic Acids Res , vol.27 , pp. 1359-1364
    • Mertin, S.1    McDowall, S.G.2    Harley, V.R.3
  • 43
    • 0033711672 scopus 로고    scopus 로고
    • Modulation of collagenase 3 in human osteoarthritic cartilage by activation of extracellular transforming growth factor beta: Role of furin convertase
    • Moldovan F, Pelletier JP, Mineau F, Dupuis M, Cloutier JM, Martel-Pelletier J. Modulation of collagenase 3 in human osteoarthritic cartilage by activation of extracellular transforming growth factor beta: role of furin convertase. Arthritis Rheum 43: 2100-2109, 2000.
    • (2000) Arthritis Rheum , vol.43 , pp. 2100-2109
    • Moldovan, F.1    Pelletier, J.P.2    Mineau, F.3    Dupuis, M.4    Cloutier, J.M.5    Martel-Pelletier, J.6
  • 44
    • 0033023434 scopus 로고    scopus 로고
    • The extracellular matrix, interstitial fluid and ions as a mechanical signal transducer in articular cartilage
    • Mow VC, Wang CC, Hung CT. The extracellular matrix, interstitial fluid and ions as a mechanical signal transducer in articular cartilage. Osteoarthritis Cartilage 7: 41-58, 1999.
    • (1999) Osteoarthritis Cartilage , vol.7 , pp. 41-58
    • Mow, V.C.1    Wang, C.C.2    Hung, C.T.3
  • 45
    • 2342457824 scopus 로고    scopus 로고
    • Control of human articular chondrocyte differentiation by reduced oxygen tension
    • Murphy CL, Polak JM. Control of human articular chondrocyte differentiation by reduced oxygen tension. J Cell Physiol 199: 451-459, 2004.
    • (2004) J Cell Physiol , vol.199 , pp. 451-459
    • Murphy, C.L.1    Polak, J.M.2
  • 46
    • 0026660354 scopus 로고
    • Identification of the fourth member of the mammalian endoprotease family homologous to the yeast Kex2 protease. Its testis-specific expression
    • Nakayama K, Kim WS, Torii S, Hosaka M, Nakagawa T, Ikemizu J, Baba T, Murakami K. Identification of the fourth member of the mammalian endoprotease family homologous to the yeast Kex2 protease. Its testis-specific expression. J Biol Chem 267: 5897-5900, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 5897-5900
    • Nakayama, K.1    Kim, W.S.2    Torii, S.3    Hosaka, M.4    Nakagawa, T.5    Ikemizu, J.6    Baba, T.7    Murakami, K.8
  • 48
    • 0034663531 scopus 로고    scopus 로고
    • The glial transcription factor Sox10 binds to DNA both as monomer and dimer with different functional consequences
    • Peirano RI, Wegner M. The glial transcription factor Sox10 binds to DNA both as monomer and dimer with different functional consequences. Nucleic Acids Res 28: 3047-3055, 2000.
    • (2000) Nucleic Acids Res , vol.28 , pp. 3047-3055
    • Peirano, R.I.1    Wegner, M.2
  • 49
    • 23644436553 scopus 로고    scopus 로고
    • Highly conserved proximal promoter element harbouring paired Sox9-binding sites contributes to the tissue- and developmental stage-specific activity of the matrilin-1 gene
    • Rentsendorj O, Nagy A, Sinko I, Daraba A, Barta E, Kiss I. Highly conserved proximal promoter element harbouring paired Sox9-binding sites contributes to the tissue- and developmental stage-specific activity of the matrilin-1 gene. Biochem J 389: 705-716, 2005.
    • (2005) Biochem J , vol.389 , pp. 705-716
    • Rentsendorj, O.1    Nagy, A.2    Sinko, I.3    Daraba, A.4    Barta, E.5    Kiss, I.6
  • 51
    • 0026053972 scopus 로고
    • Differential expression of TGF beta 1, beta 2 and beta 3 genes during mouse embryogenesis
    • Schmid P, Cox D, Bilbe G, Maier R, McMaster GK. Differential expression of TGF beta 1, beta 2 and beta 3 genes during mouse embryogenesis. Development 111: 117-130, 1991.
    • (1991) Development , vol.111 , pp. 117-130
    • Schmid, P.1    Cox, D.2    Bilbe, G.3    Maier, R.4    McMaster, G.K.5
  • 52
    • 0034646703 scopus 로고    scopus 로고
    • SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6
    • Sekiya I, Tsuji K, Koopman P, Watanabe H, Yamada Y, Shinomiya K, Nifuji A, Noda M. SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6. J Biol Chem 275: 10738-10744, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 10738-10744
    • Sekiya, I.1    Tsuji, K.2    Koopman, P.3    Watanabe, H.4    Yamada, Y.5    Shinomiya, K.6    Nifuji, A.7    Noda, M.8
  • 53
    • 0030727351 scopus 로고    scopus 로고
    • Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis
    • Serra R, Johnson M, Filvaroff EH, LaBorde J, Sheehan DM, Derynck R, Moses HL. Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis. J Cell Biol 139: 541-552, 1997.
    • (1997) J Cell Biol , vol.139 , pp. 541-552
    • Serra, R.1    Johnson, M.2    Filvaroff, E.H.3    LaBorde, J.4    Sheehan, D.M.5    Derynck, R.6    Moses, H.L.7
  • 54
    • 0030788922 scopus 로고    scopus 로고
    • Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro
    • Shukunami C, Ishizeki K, Atsumi T, Ohta Y, Suzuki F, Hiraki Y. Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro. J Bone Miner Res 12: 1174-1188, 1997.
    • (1997) J Bone Miner Res , vol.12 , pp. 1174-1188
    • Shukunami, C.1    Ishizeki, K.2    Atsumi, T.3    Ohta, Y.4    Suzuki, F.5    Hiraki, Y.6
  • 55
    • 0036197206 scopus 로고    scopus 로고
    • The life cycle of chondrocytes in the developing skeleton
    • Shum L, Nuckolls G. The life cycle of chondrocytes in the developing skeleton. Arthritis Res 4: 94-106, 2002.
    • (2002) Arthritis Res , vol.4 , pp. 94-106
    • Shum, L.1    Nuckolls, G.2
  • 57
    • 0038039240 scopus 로고    scopus 로고
    • Loss of DNA-dependent dimerization of the transcription factor SOX9 as a cause for campomelic dysplasia
    • Sock E, Pagon RA, Keymolen K, Lissens W, Wegner M, Scherer G. Loss of DNA-dependent dimerization of the transcription factor SOX9 as a cause for campomelic dysplasia. Hum Mol Genet 12: 1439-1447, 2003.
    • (2003) Hum Mol Genet , vol.12 , pp. 1439-1447
    • Sock, E.1    Pagon, R.A.2    Keymolen, K.3    Lissens, W.4    Wegner, M.5    Scherer, G.6
  • 58
    • 0031984825 scopus 로고    scopus 로고
    • Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model
    • Southard-Smith EM, Kos L, Pavan WJ. Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model. Nat Genet 18: 60-64, 1998.
    • (1998) Nat Genet , vol.18 , pp. 60-64
    • Southard-Smith, E.M.1    Kos, L.2    Pavan, W.J.3
  • 59
    • 0242710747 scopus 로고    scopus 로고
    • TACE/ADAM-17 maturation and activation of sheddase activity require proprotein convertase activity
    • Srour N, Lebel A, McMahon S, Fournier I, Fugere M, Day R, Dubois CM. TACE/ADAM-17 maturation and activation of sheddase activity require proprotein convertase activity. FEBS Lett 554: 275-283, 2003.
    • (2003) FEBS Lett , vol.554 , pp. 275-283
    • Srour, N.1    Lebel, A.2    McMahon, S.3    Fournier, I.4    Fugere, M.5    Day, R.6    Dubois, C.M.7
  • 60
    • 0036791359 scopus 로고    scopus 로고
    • Furin at the cutting edge: From protein traffic to embryogenesis and disease
    • Thomas G. Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat Rev Mol Cell Biol 3: 753-766, 2002.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 753-766
    • Thomas, G.1
  • 61
    • 0036233716 scopus 로고    scopus 로고
    • Bone morphogenetic protein signals are required for cartilage formation and differently regulate joint development during skeletogenesis
    • Tsumaki N, Nakase T, Miyaji T, Kakiuchi M, Kimura T, Ochi T, Yoshikawa H. Bone morphogenetic protein signals are required for cartilage formation and differently regulate joint development during skeletogenesis. J Bone Miner Res 17: 898-906, 2002.
    • (2002) J Bone Miner Res , vol.17 , pp. 898-906
    • Tsumaki, N.1    Nakase, T.2    Miyaji, T.3    Kakiuchi, M.4    Kimura, T.5    Ochi, T.6    Yoshikawa, H.7
  • 63
    • 0029750190 scopus 로고    scopus 로고
    • Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein
    • Vortkamp A, Lee K, Lanske B, Segre GV, Kronenberg HM, Tabin CJ. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. Science 273: 613-622, 1996.
    • (1996) Science , vol.273 , pp. 613-622
    • Vortkamp, A.1    Lee, K.2    Lanske, B.3    Segre, G.V.4    Kronenberg, H.M.5    Tabin, C.J.6
  • 65
    • 0029811142 scopus 로고    scopus 로고
    • Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation
    • Weir EC, Philbrick WM, Amling M, Neff LA, Baron R, Broadus AE. Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation. Proc Natl Acad Sci USA 93: 10240-10245, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10240-10245
    • Weir, E.C.1    Philbrick, W.M.2    Amling, M.3    Neff, L.A.4    Baron, R.5    Broadus, A.E.6
  • 66
    • 0035106841 scopus 로고    scopus 로고
    • Floppy SOX: Mutual induced fit in hmg (high-mobility group) box-DNA recognition
    • Weiss MA. Floppy SOX: mutual induced fit in hmg (high-mobility group) box-DNA recognition. Mol Endocrinol 15: 353-362, 2001.
    • (2001) Mol Endocrinol , vol.15 , pp. 353-362
    • Weiss, M.A.1
  • 67
    • 14044260735 scopus 로고    scopus 로고
    • The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development
    • Wilson MJ, Jeyasuria P, Parker KL, Koopman P. The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development. J Biol Chem 280: 5917-5923, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 5917-5923
    • Wilson, M.J.1    Jeyasuria, P.2    Parker, K.L.3    Koopman, P.4
  • 68
    • 0035795409 scopus 로고    scopus 로고
    • TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage
    • Yang X, Chen L, Xu X, Li C, Huang C, Deng CX. TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage. J Cell Biol 153: 35-46, 2001.
    • (2001) J Cell Biol , vol.153 , pp. 35-46
    • Yang, X.1    Chen, L.2    Xu, X.3    Li, C.4    Huang, C.5    Deng, C.X.6
  • 69
    • 0037414825 scopus 로고    scopus 로고
    • Regulation of human COL9A1 gene expression. Activation of the proximal promoter region by SOX9
    • Zhang P, Jimenez SA, Stokes DG. Regulation of human COL9A1 gene expression. Activation of the proximal promoter region by SOX9. J Biol Chem 278: 117-123, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 117-123
    • Zhang, P.1    Jimenez, S.A.2    Stokes, D.G.3
  • 70
    • 0028124241 scopus 로고
    • The developmental expression in rat of proteases furin, PC1, PC2, and carboxypeptidase E: Implications for early maturation of proteolytic processing capacity
    • Zheng M, Streck RD, Scott RE, Seidah NG, Pintar JE. The developmental expression in rat of proteases furin, PC1, PC2, and carboxypeptidase E: implications for early maturation of proteolytic processing capacity. J Neurosci 14: 4656-4673, 1994.
    • (1994) J Neurosci , vol.14 , pp. 4656-4673
    • Zheng, M.1    Streck, R.D.2    Scott, R.E.3    Seidah, N.G.4    Pintar, J.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.