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Volumn 293, Issue 1, 2007, Pages

A novel signaling pathway for β-adrenergic receptor-mediated activation of phosphoinositide 3-kinase in H9c2 cardiomyocytes

Author keywords

G i G ; Platelet derived growth factor receptor; Src

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; 5 [2 [[2 HYDROXY 3 [4 (1 METHYL 4 TRIFLUOROMETHYL 2 IMIDAZOLYL)PHENOXY]PROPYL]AMINO]ETHOXY]SALICYLAMIDE; 6,7 DIMETHOXY 2 PHENYLQUINOXALINE; ADENYLATE CYCLASE; ADENYLATE CYCLASE INHIBITOR; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ISOPRENALINE; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE BETA; PHOSPHATIDYLINOSITOL 3 KINASE DELTA; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; RAS PROTEIN; S6 KINASE; SMALL INTERFERING RNA; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 34547099814     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01318.2006     Document Type: Article
Times cited : (42)

References (50)
  • 1
    • 2342537099 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase γ: Kinase-dependent and -independent activities in cardiovascular function and disease
    • Alloatti G, Montrucchio G, Lembo G, Hirsch E. Phosphoinositide 3-kinase γ: kinase-dependent and -independent activities in cardiovascular function and disease. Biochem Soc Trans 32: 383-386, 2004.
    • (2004) Biochem Soc Trans , vol.32 , pp. 383-386
    • Alloatti, G.1    Montrucchio, G.2    Lembo, G.3    Hirsch, E.4
  • 2
    • 0036156765 scopus 로고    scopus 로고
    • 2+ stores in receptor signaling and antagonism by arginine vasopressin
    • 2+ stores in receptor signaling and antagonism by arginine vasopressin. J Cell Biochem 84: 736-749, 2002.
    • (2002) J Cell Biochem , vol.84 , pp. 736-749
    • Brostrom, M.A.1    Meiners, S.2    Brostrom, C.O.3
  • 3
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley LC. The phosphoinositide 3-kinase pathway. Science 296: 1655-1657, 2002.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 4
    • 0027346661 scopus 로고
    • Catecholamine receptors: Structure function, regulation
    • Caron MG, Lefkowitz RJ. Catecholamine receptors: structure function, regulation. Recent Prog Horm Res 48: 277-290, 1993.
    • (1993) Recent Prog Horm Res , vol.48 , pp. 277-290
    • Caron, M.G.1    Lefkowitz, R.J.2
  • 5
    • 0347349553 scopus 로고
    • Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system
    • Cassel D, Pfeuffer T. Mechanism of cholera toxin action: covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system. Proc Natl Acad Sci USA 75: 2669-2673, 1978.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 2669-2673
    • Cassel, D.1    Pfeuffer, T.2
  • 6
    • 0025248571 scopus 로고
    • Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-[p-bromocin-namylamino] ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells
    • Chijiwa T, Mishima A, Hagiwara M, Sano M, Hayashi K, Inoue T, Naito K, Toshioka T, Hidaka H. Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-[p-bromocin-namylamino] ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. J Biol Chem 265: 5267-5272, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 5267-5272
    • Chijiwa, T.1    Mishima, A.2    Hagiwara, M.3    Sano, M.4    Hayashi, K.5    Inoue, T.6    Naito, K.7    Toshioka, T.8    Hidaka, H.9
  • 7
    • 33749267065 scopus 로고    scopus 로고
    • c-Src couples PI 3 kinase/Akt and MAPK signaling to PDGF-induced DNA synthesis in mesangial cells
    • Choudhury GG, Mahimainathan L, Das F, Venkatesan B, Ghosh-Choudhury N. c-Src couples PI 3 kinase/Akt and MAPK signaling to PDGF-induced DNA synthesis in mesangial cells. Cell Signal 18: 1854-1864, 2006.
    • (2006) Cell Signal , vol.18 , pp. 1854-1864
    • Choudhury, G.G.1    Mahimainathan, L.2    Das, F.3    Venkatesan, B.4    Ghosh-Choudhury, N.5
  • 9
    • 0029843957 scopus 로고    scopus 로고
    • Regulation of β-adrenoceptor density and mRNA levels in the rat heart cell-line H9c2
    • Dangel V, Giray J, Ratge D, Wisser H. Regulation of β-adrenoceptor density and mRNA levels in the rat heart cell-line H9c2. Biochem J 317: 925-931, 1996.
    • (1996) Biochem J , vol.317 , pp. 925-931
    • Dangel, V.1    Giray, J.2    Ratge, D.3    Wisser, H.4
  • 12
    • 0025791965 scopus 로고
    • Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart
    • Hescheler J, Meyer R, Plant S, Krautwurst D, Rosenthal W, Schultz G. Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart. Circ Res 69: 1476-1486, 1991.
    • (1991) Circ Res , vol.69 , pp. 1476-1486
    • Hescheler, J.1    Meyer, R.2    Plant, S.3    Krautwurst, D.4    Rosenthal, W.5    Schultz, G.6
  • 14
    • 2442714117 scopus 로고    scopus 로고
    • Distinct roles for Src tyrosine kinase in β2-adrenergic receptor signaling to MAPK and in receptor internalization
    • Huang J, Sun Y, Huang XY. Distinct roles for Src tyrosine kinase in β2-adrenergic receptor signaling to MAPK and in receptor internalization. J Biol Chem 279: 21637-21642, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 21637-21642
    • Huang, J.1    Sun, Y.2    Huang, X.Y.3
  • 15
    • 0037067463 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase functionally compartmentalizes the concurrent Gs signaling during β2-adrenergic stimulation
    • Jo SH, Leblais V, Wang PH, Crow MT, Xiao RP. Phosphatidylinositol 3-kinase functionally compartmentalizes the concurrent Gs signaling during β2-adrenergic stimulation. Circ Res 91: 46-53, 2002.
    • (2002) Circ Res , vol.91 , pp. 46-53
    • Jo, S.H.1    Leblais, V.2    Wang, P.H.3    Crow, M.T.4    Xiao, R.P.5
  • 16
    • 2042444455 scopus 로고    scopus 로고
    • NHERF2 increases platelet-derived growth factor-induced proliferation through PI-3-kinase/Akt-, ERK-, and Src family kinase-dependent pathway
    • Kang YJ, Jeon ES, Lee HJ, Oh YS, Suh PG, Jung JS, Donowitz M, Kim JH. NHERF2 increases platelet-derived growth factor-induced proliferation through PI-3-kinase/Akt-, ERK-, and Src family kinase-dependent pathway. Cell Signal 16: 791-800, 2004.
    • (2004) Cell Signal , vol.16 , pp. 791-800
    • Kang, Y.J.1    Jeon, E.S.2    Lee, H.J.3    Oh, Y.S.4    Suh, P.G.5    Jung, J.S.6    Donowitz, M.7    Kim, J.H.8
  • 17
    • 0025042770 scopus 로고
    • Phosphorylation of the PDGF receptor β subunit creates a tight binding site for phosphatidylinositol 3 kinase
    • Kazlauskas A, Cooper JA. Phosphorylation of the PDGF receptor β subunit creates a tight binding site for phosphatidylinositol 3 kinase. EMBO J 9: 3279-3286, 1990.
    • (1990) EMBO J , vol.9 , pp. 3279-3286
    • Kazlauskas, A.1    Cooper, J.A.2
  • 18
    • 0037200025 scopus 로고    scopus 로고
    • β-Adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases
    • Kim J, Eckhart AD, Eguchi S, Koch WJ. β-Adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases. J Biol Chem 277: 32116-32123, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 32116-32123
    • Kim, J.1    Eckhart, A.D.2    Eguchi, S.3    Koch, W.J.4
  • 19
    • 0002680673 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase regulates differentiation of H9c2 cardiomyoblasts mainly through the protein kinase B/Akt-independent pathway
    • Kim JM, Yoon MY, Kim J, Kim SS, Kang I, Ha J, Kim SS. Phosphatidylinositol 3-kinase regulates differentiation of H9c2 cardiomyoblasts mainly through the protein kinase B/Akt-independent pathway. Arch Biochem Biophys 367: 67-73, 1999.
    • (1999) Arch Biochem Biophys , vol.367 , pp. 67-73
    • Kim, J.M.1    Yoon, M.Y.2    Kim, J.3    Kim, S.S.4    Kang, I.5    Ha, J.6    Kim, S.S.7
  • 21
    • 0027481032 scopus 로고
    • The binding site for the βγ subunits of heterotrimeric G proteins on the β-adrenergic receptor kinase
    • Koch WJ, Inglese J, Stone WC, Lefkowitz RJ. The binding site for the βγ subunits of heterotrimeric G proteins on the β-adrenergic receptor kinase. J Biol Chem 268: 8256-8260, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 8256-8260
    • Koch, W.J.1    Inglese, J.2    Stone, W.C.3    Lefkowitz, R.J.4
  • 24
    • 0034268796 scopus 로고    scopus 로고
    • Src tyrosine kinase is a novel direct effector of G proteins
    • Ma YC, Huang J, Ali S, Lowry W, Huang XY. Src tyrosine kinase is a novel direct effector of G proteins. Cell 102: 635-646, 2000.
    • (2000) Cell , vol.102 , pp. 635-646
    • Ma, Y.C.1    Huang, J.2    Ali, S.3    Lowry, W.4    Huang, X.Y.5
  • 25
    • 0032828890 scopus 로고    scopus 로고
    • βγ-induced activation of class I phosphoinositide 3-kinase isoforms β and γ
    • βγ-induced activation of class I phosphoinositide 3-kinase isoforms β and γ. J Biol Chem 274: 29311-29317, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 29311-29317
    • Maier, U.1    Babich, A.2    Nurnberg, B.3
  • 26
    • 0018773009 scopus 로고
    • Simultaneous determination of β-1 and β-2-adrenergic receptors in tissues containing both receptor subtypes
    • Minneman KP, Hegstrand LR, Molinoff PB. Simultaneous determination of β-1 and β-2-adrenergic receptors in tissues containing both receptor subtypes. Mol Pharmacol 16: 34-46, 1979.
    • (1979) Mol Pharmacol , vol.16 , pp. 34-46
    • Minneman, K.P.1    Hegstrand, L.R.2    Molinoff, P.B.3
  • 28
    • 0034640299 scopus 로고    scopus 로고
    • The Akt-glycogen synthase kinase 3β pathway regulates transcription of atrial natriuretic factor induced by β-adrenergic receptor stimulation in cardiac myocytes
    • Morisco C, Zebrowski D, Condorelli G, Tsichlis P, Vatner SF, Sadoshima J. The Akt-glycogen synthase kinase 3β pathway regulates transcription of atrial natriuretic factor induced by β-adrenergic receptor stimulation in cardiac myocytes. J Biol Chem 275: 14466-14475, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 14466-14475
    • Morisco, C.1    Zebrowski, D.2    Condorelli, G.3    Tsichlis, P.4    Vatner, S.F.5    Sadoshima, J.6
  • 29
    • 0034697121 scopus 로고    scopus 로고
    • A novel role for phosphatidylinositol 3-kinase β in signaling from G protein-coupled receptors to Akt
    • Murga C, Fukuhara S, Gutkind JS. A novel role for phosphatidylinositol 3-kinase β in signaling from G protein-coupled receptors to Akt. J Biol Chem 275: 12069-12073, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 12069-12073
    • Murga, C.1    Fukuhara, S.2    Gutkind, J.S.3
  • 30
    • 0035375104 scopus 로고    scopus 로고
    • Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by β-adrenergic receptor kinase 1. A role in receptor sequestration
    • Naga Prasad SV, Barak LS, Rapacciuolo A, Caron MG, Rockman HA. Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by β-adrenergic receptor kinase 1. A role in receptor sequestration. J Biol Chem 276: 18953-18959, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 18953-18959
    • Naga Prasad, S.V.1    Barak, L.S.2    Rapacciuolo, A.3    Caron, M.G.4    Rockman, H.A.5
  • 31
    • 0038015697 scopus 로고    scopus 로고
    • Role of phosphoinositide 3-kinase in cardiac function and heart failure
    • Naga Prasad SV, Perrino C, Rockman HA. Role of phosphoinositide 3-kinase in cardiac function and heart failure. Trends Cardiovasc Med 13: 206-212, 2003.
    • (2003) Trends Cardiovasc Med , vol.13 , pp. 206-212
    • Naga Prasad, S.V.1    Perrino, C.2    Rockman, H.A.3
  • 32
    • 85047693926 scopus 로고    scopus 로고
    • Inhibition of receptor-localized PI3K preserves cardiac β-adrenergic receptor function and ameliorates pressure overload heart failure
    • Nienaber JJ, Tachibana H, Naga Prasad SV, Esposito G, Wu D, Mao L, Rockman HA. Inhibition of receptor-localized PI3K preserves cardiac β-adrenergic receptor function and ameliorates pressure overload heart failure. J Clin Invest 112: 1067-1079, 2003.
    • (2003) J Clin Invest , vol.112 , pp. 1067-1079
    • Nienaber, J.J.1    Tachibana, H.2    Naga Prasad, S.V.3    Esposito, G.4    Wu, D.5    Mao, L.6    Rockman, H.A.7
  • 34
    • 0028198388 scopus 로고
    • Activation of phosphatidylinositol-3′ kinase by Src-family kinase SH3 binding to the p85 subunit
    • Pleiman CM, Hertz WM, Cambier JC. Activation of phosphatidylinositol-3′ kinase by Src-family kinase SH3 binding to the p85 subunit. Science 263: 1609-1612, 1994.
    • (1994) Science , vol.263 , pp. 1609-1612
    • Pleiman, C.M.1    Hertz, W.M.2    Cambier, J.C.3
  • 35
    • 0033599039 scopus 로고    scopus 로고
    • EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
    • Prenzel N, Zwick E, Daub H, Leserer M, Abraham R, Wallasch C, Ullrich A. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 402: 884-888, 1999.
    • (1999) Nature , vol.402 , pp. 884-888
    • Prenzel, N.1    Zwick, E.2    Daub, H.3    Leserer, M.4    Abraham, R.5    Wallasch, C.6    Ullrich, A.7
  • 36
    • 0029148780 scopus 로고
    • G protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase. Shc adapter protein signaling complexes
    • Ptasznik A, Traynor-Kaplan A, Bokoch GM. G protein-coupled chemoattractant receptors regulate Lyn tyrosine kinase. Shc adapter protein signaling complexes. J Biol Chem 270: 19969-19973, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 19969-19973
    • Ptasznik, A.1    Traynor-Kaplan, A.2    Bokoch, G.M.3
  • 37
    • 0037050009 scopus 로고    scopus 로고
    • Seven-transmembrane-spanning receptors and heart function
    • Rockman HA, Koch WJ, Lefkowitz RJ. Seven-transmembrane-spanning receptors and heart function. Nature 415: 206-212, 2002.
    • (2002) Nature , vol.415 , pp. 206-212
    • Rockman, H.A.1    Koch, W.J.2    Lefkowitz, R.J.3
  • 39
    • 0031452274 scopus 로고    scopus 로고
    • Structures of Src-family tyrosine kinases
    • Sicheri F, Kuriyan J. Structures of Src-family tyrosine kinases. Curr Opin Struct Biol 7: 777-785, 1997.
    • (1997) Curr Opin Struct Biol , vol.7 , pp. 777-785
    • Sicheri, F.1    Kuriyan, J.2
  • 40
    • 0020538987 scopus 로고
    • Three loci related to the Src oncogene and tyrosine-specific protein kinase activity in Drosophila
    • Simon MA, Kornberg TB, Bishop JM. Three loci related to the Src oncogene and tyrosine-specific protein kinase activity in Drosophila. Nature 302: 837-839, 1983.
    • (1983) Nature , vol.302 , pp. 837-839
    • Simon, M.A.1    Kornberg, T.B.2    Bishop, J.M.3
  • 42
    • 0027285860 scopus 로고    scopus 로고
    • Stephens L, Eguinoa A, Corey S, Jackson T, Hawkins PT. Receptor stimulated accumulation of phosphatidylinositol (3, 4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells. EMBO J 12: 2265-2273, 1993.
    • Stephens L, Eguinoa A, Corey S, Jackson T, Hawkins PT. Receptor stimulated accumulation of phosphatidylinositol (3, 4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells. EMBO J 12: 2265-2273, 1993.
  • 48
    • 0027250720 scopus 로고
    • 2+ current in single rat ventricular cells
    • 2+ current in single rat ventricular cells. Circ Res 73: 286-300, 1993.
    • (1993) Circ Res , vol.73 , pp. 286-300
    • Xiao, R.P.1    Lakatta, E.G.2
  • 49
    • 28044451344 scopus 로고    scopus 로고
    • Emerging concepts and therapeutic implications of β-adrenergic receptor subtype signaling
    • Zheng M, Zhu W, Han Q, Xiao RP. Emerging concepts and therapeutic implications of β-adrenergic receptor subtype signaling. Pharmacol Ther 108: 257-268, 2005.
    • (2005) Pharmacol Ther , vol.108 , pp. 257-268
    • Zheng, M.1    Zhu, W.2    Han, Q.3    Xiao, R.P.4
  • 50
    • 0033515118 scopus 로고    scopus 로고
    • Both Gs and Gi proteins are critically involved in isoproterenol-induced cardiomyocyte hypertrophy
    • Zou Y, Komuro I, Yamazaki T, Kudoh S, Uozumi H, Kadowaki T, Yazaki Y. Both Gs and Gi proteins are critically involved in isoproterenol-induced cardiomyocyte hypertrophy. J Biol Chem 274: 9760-9770, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 9760-9770
    • Zou, Y.1    Komuro, I.2    Yamazaki, T.3    Kudoh, S.4    Uozumi, H.5    Kadowaki, T.6    Yazaki, Y.7


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