DNA topoisomerase II selects DNA cleavage sites based on reactivity rather than binding affinity

Nucleic Acids Research

Volumn 35, Issue 11, 2007, Pages 3764-3773

  Mueller Planitz, Felix ^a,b   Herschlag, Daniel ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA TOPOISOMERASE (ATP HYDROLYSING); DOUBLE STRANDED DNA; GENOMIC DNA; PLASMID DNA; DNA BINDING PROTEIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA BINDING; DNA CLEAVAGE; DNA DEGRADATION; DNA SEQUENCE; DNA STRAND BREAKAGE; DNA STRUCTURE; ENZYME DEGRADATION; ENZYME STRUCTURE; GENE MAPPING; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; SACCHAROMYCES CEREVISIAE; BINDING SITE; CHEMISTRY; ENZYME SPECIFICITY; KINETICS; METABOLISM; PROTEIN CONFORMATION; THERMODYNAMICS;

BINDING SITES; DNA; DNA TOPOISOMERASES, TYPE II, EUKARYOTIC; DNA-BINDING PROTEINS; KINETICS; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 34547096540     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkm335     Document Type: Article

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