A novel design of a noncylindric stent with beneficial effects on flow characteristics: An experimental and numerical flow study in an axisymmetric arterial model with sequential mild stenoses

Artificial Organs

Volumn 31, Issue 8, 2007, Pages 627-638

  Papaioannou, Theodore G ^a,b,c   Christofidis, Charalambos Ch ^a   Mathioulakis, Demetri S ^a   Stefanadis, Christodoulos I ^b  

^a NATIONAL TECHNICAL UNIVERSITY OF ATHENS   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

^c NONE   (Greece)

Author keywords

Computational fluid dynamics; Coronary flow; Flow visualization; In stent; Intravascular devices; Ostial lesions; Recirculation; Restenosis; Separation zones

Indexed keywords

DISEASES; FLOW VELOCITY; FLOW VISUALIZATION; GEOMETRY; REYNOLDS NUMBER; SHEAR FLOW; SHEAR STRESS; STENTS; UNSTEADY FLOW;

CORONARY FLOW; FLOW VISUALISATION; IN-STENT; INTRAVASCULAR DEVICES; OSTIAL LESION; RECIRCULATIONS; RESTENOSIS; SEPARATION ZONE; WALL SHEAR STRESS; WALL-SHEAR STRESS;

COMPUTATIONAL FLUID DYNAMICS;

ARTERY BLOOD FLOW; ARTERY OCCLUSION; ARTICLE; CIRCULATION; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; DEVICE; FLOW RATE; GEOMETRY; MATHEMATICAL ANALYSIS; PRIORITY JOURNAL; RESTENOSIS; SHEAR STRESS; STENT; TUBE;

EID: 34547094560     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2007.00431.x     Document Type: Article

References (37)

1. Berliner JA, Navab M, Fogelman AM, et al. Atherosclerosis: basic mechanisms. Oxidation, inflammation, and genetics. Circulation 1995 91 : 2488 96.
2. Karatzis EN. The role of inflammatory agents in endothelial function and their contribution to atherosclerosis. Hellenic J Cardiol 2005 46 : 232 9.
3. Malek AM, Alper SL, Izumo S. Hemodynamic shear stress and its role in atherosclerosis. JAMA 1999 282 : 2035 42.
4. Deng X, King MW, Guidoin R. Localization of atherosclerosis in arterial junctions. Concentration distribution of low density lipoproteins at the luminal surface in regions of disturbed flow. ASAIO J 1995 41 : 58 67.
5. Papaioannou TG, Karatzis EN, Vavuranakis M, Lekakis JP, Stefanadis C. Assessment of vascular wall shear stress and implications for atherosclerotic disease. Int J Cardiol 2006 113 : 12 8.
6. Stone PH, Coskun AU, Kinlay S, et al. Effect of endothelial shear stress on the progression of coronary artery disease, vascular remodeling, and in-stent restenosis in humans: in vivo 6-month follow-up study. Circulation 2003 108 : 438 44.
7. Lee KW, Xu XY. Modelling of flow and wall behaviour in a mildly stenosed tube. Med Eng Phys 2002 24 : 575 86.
8. Deplano V, Siouffi M. Experimental and numerical study of pulsatile flows through stenosis: wall shear stress analysis. J Biomech 1999 32 : 1081 90.
9. Mates RE, Gupta RL, Bell AC, Klocke FJ. Fluid dynamics of coronary artery stenosis. Circ Res 1978 42 : 152 62.
10. Young DF, Tsai FY. Flow characteristics in models of arterial stenoses. I. Steady flow. J Biomech 1973 6 : 395 410.
11. Barbato E, Marco J, Wijns W. Direct stenting. Eur Heart J 2003 24 : 394 403.
12. Colombo A, Stankovic G, Moses JW. Selection of coronary stents. J Am Coll Cardiol 2002 40 : 1021 33.
13. Tan KH, Sulke N, Taub N, Sowton E. Percutaneous transluminal coronary angioplasty of aorta ostial, non-aorta ostial, and branch ostial stenoses: acute and long-term outcome. Eur Heart J 1995 16 : 631 9.
14. De Cesare NB, Bartorelli AL, Galli S, et al. Treatment of ostial lesions of the left anterior descending coronary artery with Palmaz-Schatz coronary stent. Am Heart J 1996 132 : 716 20.
15. Bramucci E, Repetto A, Ferrario M, et al. Effectiveness of adjunctive stent implantation following directional coronary atherectomy for treatment of left anterior descending ostial stenosis. Am J Cardiol 2002 90 : 1074 8.
16. Tsagalou E, Stancovic G, Iakovou I, et al. Early outcome of treatment of ostial de novo left anterior descending coronary artery lesions with drug-eluting stents. Am J Cardiol 2006 97 : 187 91.
17. Kullo IJ, Edwards WD, Schwartz RS. Vulnerable plaque: pathobiology and clinical implications. Ann Intern Med 1998 129 : 1050 60.
18. Petropoulakis PN, Pavlides GS, Manginas AN, Vassilikos VS, Cokkinos DV. Intracoronary flow velocity measurements in adjacent stenotic and normal coronary arteries during incremental intravenous dobutamine stress and intracoronary adenosine injection. Catheter Cardiovasc Interv 1999 48 : 1 9.
19. O'Connor NJ, Morton JR, Birkmeyer JD, Olmstead EM, O'Connor GT. Effect of coronary artery diameter in patients undergoing coronary bypass surgery. Northern New England Cardiovascular Disease Study Group. Circulation 1996 93 : 652 5.
20. Nichols WW, O'Rourke MF. The coronary circulation. In : McDonald's Blood Flow in Arteries: Theoretical Experimental and Clinical Principles, 5th Edition. London : Hodder Arnold, 2005 321 37.
21. Nikolaidis NM, Mathioulakis DS. Axial and secondary flow study in a 90 deg bifurcation under pulsating conditions using PIV. J Fluid Eng Trans ASME 2002 124 : 505 11.
22. Papaioannou TG, Stefanadis C. Vascular wall shear stress: basic principles and methods. Hellenic J Cardiol 2005 46 : 9 15.
23. Carlier SG, van Damme LC, Blommerde CP, et al. Augmentation of wall shear stress inhibits neointimal hyperplasia after stent implantation: inhibition through reduction of inflammation? Circulation 2003 107 : 2741 6.
24. Young DF, Tsai FY. Flow characteristics in models of arterial stenoses. II. Unsteady flow. J Biomech 1973 6 : 547 59.
25. Cassanova RA, Giddens DP. Disorder distal to modeled stenoses in steady and pulsatile flow. J Biomech 1978 11 : 441 53.
26. Cunningham KS, Gotlieb AI. The role of shear stress in the pathogenesis of atherosclerosis. Lab Invest 2005 85 : 9 23.
27. Duraiswamy N, Jayachandran B, Byrne J, Moore JE, Jr., Schoephoerster RT. Spatial distribution of platelet deposition in stented arterial models under physiologic flow. Ann Biomed Eng 2005 33 : 1767 77.
28. Huang HL, Hsieh IC, Chang SH, et al. Acute and long-term outcomes of intracoronary stenting in aorto-ostial, left anterior descending artery-ostial and nonostial stenoses. Int J Cardiol 2005 101 : 391 7.
29. Iakovou I, Ge L, Michev I, et al. Clinical and angiographic outcome after sirolimus-eluting stent implantation in aorto-ostial lesions. J Am Coll Cardiol 2004 44 : 967 71.
30. Sousa JE, Serruys PW, Costa MA. New frontiers in cardiology: drug-eluting stents: part II. Circulation 2003 107 : 2383 9.
31. Zampieri P, Colombo A, Almagor Y, Maiello L, Finci L. Results of coronary stenting of ostial lesions. Am J Cardiol 1994 73 : 901 3.
32. Tang D, Yang C, Kobayashi S, Zheng J, Vito RP. Effect of stenosis asymmetry on blood flow and artery compression: a three-dimensional fluid-structure interaction model. Ann Biomed Eng 2003 31 : 1182 93.
33. Hara H, Nakamura M, Palmaz JC, Schwartz RS. Role of stent design and coatings on restenosis and thrombosis. Adv Drug Deliv Rev 2006 58 : 377 86.
34. Kitagawa T, Fujii T, Tomohiro Y, et al. Noninvasive assessment of coronary stents in patients by 16-slice computed tomography. Int J Cardiol 2006 109 : 188 94.
35. Frank AO, Walsh PW, Moore JE, Jr. Computational fluid dynamics and stent design. Artif Organs 2002 26 : 614 21.
36. Reneman RS, Arts T, Hoeks AP. Wall shear stress - an important determinant of endothelial cell function and structure - in the arterial system in vivo. Discrepancies with theory. J Vasc Res 2006 43 : 251 69.
37. Segers P, Kostopoulos K, De Scheerder I, Verdonck P. Biomechanical aspects of intracoronary stents. In : Verdonck P, ed. Intra and Extracorporeal Fluid Dynamics: General Principles in Application. Southampton, UK : Computational Mechanics Publications, 1998 203 32.