메뉴 건너뛰기




Volumn 188, Issue 1-2, 2007, Pages 86-94

Ets-1 represents a pivotal transcription factor for viral clearance, inflammation, and demyelination in a mouse model of multiple sclerosis

Author keywords

Astrocyte; Ets 1; Immunohistochemistry; Mouse strain; RT qPCR; Theiler's murine encephalomyelitis

Indexed keywords

MESSENGER RNA; TRANSCRIPTION FACTOR ETS 1;

EID: 34447647277     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2007.05.019     Document Type: Article
Times cited : (31)

References (63)
  • 1
    • 0029761977 scopus 로고    scopus 로고
    • Up-regulation of major histocompatibility complex class II antigen expression in the central nervous system of dogs with spontaneous canine distemper virus encephalitis
    • Alldinger S., Wünschmann A., Baumgärtner W., Voss C., and Kremmer E. Up-regulation of major histocompatibility complex class II antigen expression in the central nervous system of dogs with spontaneous canine distemper virus encephalitis. Acta Neuropathol. 92 (1996) 273-280
    • (1996) Acta Neuropathol. , vol.92 , pp. 273-280
    • Alldinger, S.1    Wünschmann, A.2    Baumgärtner, W.3    Voss, C.4    Kremmer, E.5
  • 2
  • 3
    • 0030966101 scopus 로고    scopus 로고
    • The role of ETS transcription factors in the development and function of the mammalian immune system
    • Bassuk A.G., and Leiden J.M. The role of ETS transcription factors in the development and function of the mammalian immune system. Adv. Immunol. 64 (1997) 65-104
    • (1997) Adv. Immunol. , vol.64 , pp. 65-104
    • Bassuk, A.G.1    Leiden, J.M.2
  • 4
    • 0032532022 scopus 로고    scopus 로고
    • Differential expression of inflammatory cytokines parallels progression of central nervous system pathology in two clinically distinct models of multiple sclerosis
    • Begolka W.S., Vanderlugt C.L., Rahbe S.M., and Miller S.D. Differential expression of inflammatory cytokines parallels progression of central nervous system pathology in two clinically distinct models of multiple sclerosis. J. Immunol. 161 (1998) 4437-4446
    • (1998) J. Immunol. , vol.161 , pp. 4437-4446
    • Begolka, W.S.1    Vanderlugt, C.L.2    Rahbe, S.M.3    Miller, S.D.4
  • 6
    • 0028880729 scopus 로고
    • Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene
    • Bories J.-D., Willerford D.M., Grévin D., Davidson L., Camus A., Martin P., Stéhelin D., and Alt F.W. Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene. Nature 377 (1995) 635-638
    • (1995) Nature , vol.377 , pp. 635-638
    • Bories, J.-D.1    Willerford, D.M.2    Grévin, D.3    Davidson, L.4    Camus, A.5    Martin, P.6    Stéhelin, D.7    Alt, F.W.8
  • 8
    • 0034534911 scopus 로고    scopus 로고
    • Differential expression of TGF-β, Il-2, and other cytokines in the CNS of Theiler's murine encephalomyelitis virus-infected susceptible and resistant strains of mice
    • Chang J.R., Zaczynska E., Katsetos D., Platsoucas C.D., and Oleszak E.L. Differential expression of TGF-β, Il-2, and other cytokines in the CNS of Theiler's murine encephalomyelitis virus-infected susceptible and resistant strains of mice. Virology 278 (2000) 346-360
    • (2000) Virology , vol.278 , pp. 346-360
    • Chang, J.R.1    Zaczynska, E.2    Katsetos, D.3    Platsoucas, C.D.4    Oleszak, E.L.5
  • 10
    • 29844455077 scopus 로고    scopus 로고
    • A comparison of immunohistochemical and silver staining methods for the detection of diffuse plaques in the aged canine brain
    • Czasch S., Paul S., and Baumgärtner W. A comparison of immunohistochemical and silver staining methods for the detection of diffuse plaques in the aged canine brain. Neurobiol. Aging 27 (2006) 293-305
    • (2006) Neurobiol. Aging , vol.27 , pp. 293-305
    • Czasch, S.1    Paul, S.2    Baumgärtner, W.3
  • 11
    • 0033963940 scopus 로고    scopus 로고
    • Lymphocytes from mice chronically infected with Theiler's murine encephalomyelitis virus produce demyelination of organotypic cultures after stimulation with the major encephalitogenic epitope of myelin proteolipid protein. Epitope spreading in TMEV infection has functional activity
    • DalCanto M.C., Calenoff M.A., Miller S.D., and Vanderlugt C.L. Lymphocytes from mice chronically infected with Theiler's murine encephalomyelitis virus produce demyelination of organotypic cultures after stimulation with the major encephalitogenic epitope of myelin proteolipid protein. Epitope spreading in TMEV infection has functional activity. J. Neuroimmunol. 104 (2000) 79-84
    • (2000) J. Neuroimmunol. , vol.104 , pp. 79-84
    • DalCanto, M.C.1    Calenoff, M.A.2    Miller, S.D.3    Vanderlugt, C.L.4
  • 12
    • 0035153212 scopus 로고    scopus 로고
    • Immune functions of astrocytes
    • Dong Y., and Benveniste E.N. Immune functions of astrocytes. Glia 36 (2001) 180-190
    • (2001) Glia , vol.36 , pp. 180-190
    • Dong, Y.1    Benveniste, E.N.2
  • 14
    • 26844579328 scopus 로고    scopus 로고
    • Spatio-temporal expression of immediate early genes in the central nervous system of SJL/J mice
    • Gerhauser I., Alldinger S., Ulrich R., and Baumgärtner W. Spatio-temporal expression of immediate early genes in the central nervous system of SJL/J mice. Int. J. Dev. Neurosci. 23 (2005) 637-649
    • (2005) Int. J. Dev. Neurosci. , vol.23 , pp. 637-649
    • Gerhauser, I.1    Alldinger, S.2    Ulrich, R.3    Baumgärtner, W.4
  • 15
    • 34447645221 scopus 로고    scopus 로고
    • Gerhauser, I., Ulrich, R., Alldinger, S., Baumgärtner, W., in press. Induction of AP-1 and NF-κB as a prerequisite for disease development in susceptible SJL/J mice following Theiler's murine encephalomyelitis. J. Neuropathol. Exp. Neurol.
  • 16
    • 14244251950 scopus 로고    scopus 로고
    • Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses
    • Grenningloh R., Kang B.Y., and Ho I.-C. Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses. J. Exp. Med. 201 (2005) 615-626
    • (2005) J. Exp. Med. , vol.201 , pp. 615-626
    • Grenningloh, R.1    Kang, B.Y.2    Ho, I.-C.3
  • 17
    • 0034596586 scopus 로고    scopus 로고
    • Interleukin-1β, -6, -12 and tumor necrosis factor-α expression in brains of dogs with canine distemper virus infection
    • Gröne A., Alldinger S., and Baumgärtner W. Interleukin-1β, -6, -12 and tumor necrosis factor-α expression in brains of dogs with canine distemper virus infection. J. Neuroimmunol. 110 (2000) 20-30
    • (2000) J. Neuroimmunol. , vol.110 , pp. 20-30
    • Gröne, A.1    Alldinger, S.2    Baumgärtner, W.3
  • 18
    • 0032078695 scopus 로고    scopus 로고
    • Gender variations in early Theiler's virus induced demyelinating disease: differential susceptibility and effects of IL-4, IL-10 and combined IL-4 with IL-10
    • Hill K.E., Pigmans M., Fujinami R.S., and Rose J.W. Gender variations in early Theiler's virus induced demyelinating disease: differential susceptibility and effects of IL-4, IL-10 and combined IL-4 with IL-10. J. Neuroimmunol. 85 (1998) 44-51
    • (1998) J. Neuroimmunol. , vol.85 , pp. 44-51
    • Hill, K.E.1    Pigmans, M.2    Fujinami, R.S.3    Rose, J.W.4
  • 20
    • 0034093737 scopus 로고    scopus 로고
    • Signal transduction by the TCR for antigen
    • Kane L.P., Lin J., and Weiss A. Signal transduction by the TCR for antigen. Curr. Opin. Immunol. 12 (2000) 242-249
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 242-249
    • Kane, L.P.1    Lin, J.2    Weiss, A.3
  • 22
    • 0034327178 scopus 로고    scopus 로고
    • Temporal development of autoreactive Th1 responses and endogenous presentation of self myelin epitopes by central nervous system-resident APCs in Theiler' virus-infected mice
    • Katz-Levy Y., Neville K.L., Padilla J., Rahbe S., Begolka W.S., Girvin A.M., Olson J.K., Vanderlugt C.L., and Miller S.D. Temporal development of autoreactive Th1 responses and endogenous presentation of self myelin epitopes by central nervous system-resident APCs in Theiler' virus-infected mice. J. Immunol. 165 (2000) 5304-5314
    • (2000) J. Immunol. , vol.165 , pp. 5304-5314
    • Katz-Levy, Y.1    Neville, K.L.2    Padilla, J.3    Rahbe, S.4    Begolka, W.S.5    Girvin, A.M.6    Olson, J.K.7    Vanderlugt, C.L.8    Miller, S.D.9
  • 23
    • 11244294659 scopus 로고    scopus 로고
    • Innate immune response induced by Theiler's murine encephalomyelitis virus infection
    • Kim B.S., Palma J.P., Kwon D., and Fuller A.C. Innate immune response induced by Theiler's murine encephalomyelitis virus infection. Immunol. Res. 31 (2005) 1-12
    • (2005) Immunol. Res. , vol.31 , pp. 1-12
    • Kim, B.S.1    Palma, J.P.2    Kwon, D.3    Fuller, A.C.4
  • 24
    • 0027214067 scopus 로고
    • The Ets-1 transcription factor is widely expressed during murine embryo development and is associated with mesodermal cells involved in morphogenetic processes such as organ formation
    • Kola I., Brookes S., Green A.R., Garber R., Tymms M., Papas T.S., and Seth A. The Ets-1 transcription factor is widely expressed during murine embryo development and is associated with mesodermal cells involved in morphogenetic processes such as organ formation. Proc. Natl. Acad. Sci. 90 (1993) 7588-7592
    • (1993) Proc. Natl. Acad. Sci. , vol.90 , pp. 7588-7592
    • Kola, I.1    Brookes, S.2    Green, A.R.3    Garber, R.4    Tymms, M.5    Papas, T.S.6    Seth, A.7
  • 25
    • 0028931318 scopus 로고
    • Regulation of the human TNF promoter by the transcription factor Ets
    • Kramer B., Wiegmann K., and Kronke M. Regulation of the human TNF promoter by the transcription factor Ets. J. Biol. Chem. 270 (1995) 6577-6583
    • (1995) J. Biol. Chem. , vol.270 , pp. 6577-6583
    • Kramer, B.1    Wiegmann, K.2    Kronke, M.3
  • 26
    • 0027479438 scopus 로고
    • Requirement of an ETS-binding element for transcription of the human lck type I promoter
    • Leung S., McCracken S., Ghysdael J., and Miyamoto N.G. Requirement of an ETS-binding element for transcription of the human lck type I promoter. Oncogene 8 (1993) 989-997
    • (1993) Oncogene , vol.8 , pp. 989-997
    • Leung, S.1    McCracken, S.2    Ghysdael, J.3    Miyamoto, N.G.4
  • 27
    • 0034842248 scopus 로고    scopus 로고
    • The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis
    • Lindberg R.L.P., de Groot C.J.A., Montagne L., Freitag P., van der Valk P., Kappos L., and Leppert D. The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis. Brain 124 (2001) 1743-1753
    • (2001) Brain , vol.124 , pp. 1743-1753
    • Lindberg, R.L.P.1    de Groot, C.J.A.2    Montagne, L.3    Freitag, P.4    van der Valk, P.5    Kappos, L.6    Leppert, D.7
  • 28
    • 0028902180 scopus 로고
    • The predominant virus antigen burden is present in macrophages in Theiler's murine encephalomyelitis virus-induced demyelinating disease
    • Lipton H.L., Twaddle G., and Jelachich M.L. The predominant virus antigen burden is present in macrophages in Theiler's murine encephalomyelitis virus-induced demyelinating disease. J. Virol. 69 (1995) 2525-2533
    • (1995) J. Virol. , vol.69 , pp. 2525-2533
    • Lipton, H.L.1    Twaddle, G.2    Jelachich, M.L.3
  • 29
    • 21344444595 scopus 로고    scopus 로고
    • Theiler's virus persistence in the central nervous system of mice is associated with continuous viral replication and a difference in outcome of infection of infiltrating macrophages versus oligodendrocytes
    • Lipton H.L., Kumar A.S., and Trottier M. Theiler's virus persistence in the central nervous system of mice is associated with continuous viral replication and a difference in outcome of infection of infiltrating macrophages versus oligodendrocytes. Virus Res. 111 (2005) 214-223
    • (2005) Virus Res. , vol.111 , pp. 214-223
    • Lipton, H.L.1    Kumar, A.S.2    Trottier, M.3
  • 30
    • 0028876328 scopus 로고
    • Release of myelin basic protein-degrading proteolytic activity from microglia and macrophages after infection with Theiler's murine encephalomyelitis virus: comparison between susceptible and resistant mice
    • Liuzzi G.M., Riccio P., and Dal Canto M.C. Release of myelin basic protein-degrading proteolytic activity from microglia and macrophages after infection with Theiler's murine encephalomyelitis virus: comparison between susceptible and resistant mice. J. Neuroimmunol. 62 (1995) 91-102
    • (1995) J. Neuroimmunol. , vol.62 , pp. 91-102
    • Liuzzi, G.M.1    Riccio, P.2    Dal Canto, M.C.3
  • 31
    • 0142258022 scopus 로고    scopus 로고
    • Microglia are activated to become competent antigen presenting and effector cells in the inflammatory environment of the Theiler's virus model of multiple sclerosis
    • Mack C.L., Vanderlugt-Castaneda C.L., Neville K.L., and Miller S.D. Microglia are activated to become competent antigen presenting and effector cells in the inflammatory environment of the Theiler's virus model of multiple sclerosis. J. Neuroimmunol. 144 (2003) 68-79
    • (2003) J. Neuroimmunol. , vol.144 , pp. 68-79
    • Mack, C.L.1    Vanderlugt-Castaneda, C.L.2    Neville, K.L.3    Miller, S.D.4
  • 32
    • 0036229878 scopus 로고    scopus 로고
    • Increased expression of pro-inflammatory cytokines and lack of up-regulation of anti-inflammatory cytokines in early distemper CNS lesions
    • Markus S., Failing K., and Baumgärtner W. Increased expression of pro-inflammatory cytokines and lack of up-regulation of anti-inflammatory cytokines in early distemper CNS lesions. J. Neuroimmunol. 125 (2002) 30-41
    • (2002) J. Neuroimmunol. , vol.125 , pp. 30-41
    • Markus, S.1    Failing, K.2    Baumgärtner, W.3
  • 33
    • 0034684616 scopus 로고    scopus 로고
    • Expression and function of ETS transcription factors in mammalian development: a regulatory network
    • Maroulakou I.G., and Bowe D.B. Expression and function of ETS transcription factors in mammalian development: a regulatory network. Oncogene 19 (2000) 6432-6442
    • (2000) Oncogene , vol.19 , pp. 6432-6442
    • Maroulakou, I.G.1    Bowe, D.B.2
  • 34
    • 0142092700 scopus 로고    scopus 로고
    • Phase-dependent expression of matrix-metalloproteinases and their inhibitors in demyelinating canine distemper encephalitis
    • Miao Q., Baumgärtner W., Failing K., and Alldinger S. Phase-dependent expression of matrix-metalloproteinases and their inhibitors in demyelinating canine distemper encephalitis. Acta Neuropathol. 106 (2003) 486-494
    • (2003) Acta Neuropathol. , vol.106 , pp. 486-494
    • Miao, Q.1    Baumgärtner, W.2    Failing, K.3    Alldinger, S.4
  • 35
    • 0034988223 scopus 로고    scopus 로고
    • Multiple pathways to induction of virus-induced autoimmune demyelination: lessons from Theiler's virus infection
    • Miller S.D., Olson J.K., and Croxford J.L. Multiple pathways to induction of virus-induced autoimmune demyelination: lessons from Theiler's virus infection. J. Autoimmun. 16 (2001) 219-227
    • (2001) J. Autoimmun. , vol.16 , pp. 219-227
    • Miller, S.D.1    Olson, J.K.2    Croxford, J.L.3
  • 36
    • 33747434851 scopus 로고    scopus 로고
    • Initial capsid-specific CD4+ T cell responses protect against Theiler's murine encephalomyelitis virus-induced demyelinating disease
    • Mohindru M., Kang B., and Kim B.S. Initial capsid-specific CD4+ T cell responses protect against Theiler's murine encephalomyelitis virus-induced demyelinating disease. Eur. J. Immunol. 36 (2006) 2106-2115
    • (2006) Eur. J. Immunol. , vol.36 , pp. 2106-2115
    • Mohindru, M.1    Kang, B.2    Kim, B.S.3
  • 37
    • 0028864666 scopus 로고
    • Defective activation and survival of T cells lacking the Ets-1 transcription factor
    • Muthusamy N., Barton K., and Leiden J.M. Defective activation and survival of T cells lacking the Ets-1 transcription factor. Nature 377 (1995) 639-642
    • (1995) Nature , vol.377 , pp. 639-642
    • Muthusamy, N.1    Barton, K.2    Leiden, J.M.3
  • 38
    • 0242268130 scopus 로고    scopus 로고
    • Apoptosis of infiltrating T cells in the central nervous system of mice infected with Theiler's murine encephalomyelitis virus
    • Oleszak E.L., Hoffman B.E., Chang J.R., Zaczynska E., Gaughan J., Katsetos C.D., Platsoucas S.D., and Harvey N. Apoptosis of infiltrating T cells in the central nervous system of mice infected with Theiler's murine encephalomyelitis virus. Virology 315 (2003) 110-123
    • (2003) Virology , vol.315 , pp. 110-123
    • Oleszak, E.L.1    Hoffman, B.E.2    Chang, J.R.3    Zaczynska, E.4    Gaughan, J.5    Katsetos, C.D.6    Platsoucas, S.D.7    Harvey, N.8
  • 40
    • 33846023658 scopus 로고    scopus 로고
    • Roxithromycin inhibits tumor necrosis factor-alpha-induced matrix metalloproteinase-1 expression through regulating mitogen-activated protein kinase phosphorylation and Ets-1 expression
    • Oyama T., Matsushita K., Sakuta T., Tokuda M., Tatsuyama S., Nagaoka S., and Torii M. Roxithromycin inhibits tumor necrosis factor-alpha-induced matrix metalloproteinase-1 expression through regulating mitogen-activated protein kinase phosphorylation and Ets-1 expression. J. Periodontal Res. 42 (2007) 53-61
    • (2007) J. Periodontal Res. , vol.42 , pp. 53-61
    • Oyama, T.1    Matsushita, K.2    Sakuta, T.3    Tokuda, M.4    Tatsuyama, S.5    Nagaoka, S.6    Torii, M.7
  • 41
    • 0037689117 scopus 로고    scopus 로고
    • Infection with Theiler's murine encephalomyelitis virus directly induces proinflammatory cytokines in primary astrocytes via NF-κB activation: potential role for the initiation of demyelinating disease
    • Palma J.P., Kwon D., Clipstone N.A., and Kim B.S. Infection with Theiler's murine encephalomyelitis virus directly induces proinflammatory cytokines in primary astrocytes via NF-κB activation: potential role for the initiation of demyelinating disease. J. Virol. 77 (2003) 6322-6331
    • (2003) J. Virol. , vol.77 , pp. 6322-6331
    • Palma, J.P.1    Kwon, D.2    Clipstone, N.A.3    Kim, B.S.4
  • 42
    • 1942457284 scopus 로고    scopus 로고
    • + double positive (DP) T cells in health and disease
    • + double positive (DP) T cells in health and disease. Autoimmun. Rev. 3 (2004) 215-220
    • (2004) Autoimmun. Rev. , vol.3 , pp. 215-220
    • Parel, Y.1    Chizzolini, C.2
  • 43
    • 0023988452 scopus 로고
    • Mitogenic stimulation of thymocytes results in the calcium-dependent phosphorylation of c-ets-1 proteins
    • Pognonec P., Boulukos K.E., Gesquière J.C., Stéhelin D., and Ghysdael J. Mitogenic stimulation of thymocytes results in the calcium-dependent phosphorylation of c-ets-1 proteins. EMBO J. 7 (1988) 977-983
    • (1988) EMBO J. , vol.7 , pp. 977-983
    • Pognonec, P.1    Boulukos, K.E.2    Gesquière, J.C.3    Stéhelin, D.4    Ghysdael, J.5
  • 45
    • 0036737795 scopus 로고    scopus 로고
    • Matrix metalloproteinases in neuroinflammation
    • Rosenberg G.A. Matrix metalloproteinases in neuroinflammation. Glia 39 (2002) 279-291
    • (2002) Glia , vol.39 , pp. 279-291
    • Rosenberg, G.A.1
  • 47
    • 0034674653 scopus 로고    scopus 로고
    • Glucocorticoids suppress tumor necrosis factor-alpha expression by human monocytic THP-1 cells by suppressing transactivation through adjacent NF-kappa B and c-Jun-activating transcription factor-2 binding sites in the promoter
    • Steer J.H., Kroeger K.M., Abraham L.J., and Joyce D.A. Glucocorticoids suppress tumor necrosis factor-alpha expression by human monocytic THP-1 cells by suppressing transactivation through adjacent NF-kappa B and c-Jun-activating transcription factor-2 binding sites in the promoter. J. Biol. Chem. 275 (2000) 18432-18440
    • (2000) J. Biol. Chem. , vol.275 , pp. 18432-18440
    • Steer, J.H.1    Kroeger, K.M.2    Abraham, L.J.3    Joyce, D.A.4
  • 48
    • 33750743068 scopus 로고    scopus 로고
    • Dissecting natural killer cell activation pathways through analysis of genetic mutation in human and mouse
    • Tassi I., Klesney-Tait J., and Colonna M. Dissecting natural killer cell activation pathways through analysis of genetic mutation in human and mouse. Immunol. Rev. 214 (2006) 92-105
    • (2006) Immunol. Rev. , vol.214 , pp. 92-105
    • Tassi, I.1    Klesney-Tait, J.2    Colonna, M.3
  • 49
    • 0000667972 scopus 로고
    • Spontaneous encephalomyelitis of mice-a new virus disease
    • Theiler M. Spontaneous encephalomyelitis of mice-a new virus disease. Science 80 (1934) 122-123
    • (1934) Science , vol.80 , pp. 122-123
    • Theiler, M.1
  • 50
    • 0036271301 scopus 로고    scopus 로고
    • Theiler's virus-mediated autoimmunity: local presentation of CNS antigens and epitope spreading
    • Tompkins S.M., Fuller K.G., and Miller S.D. Theiler's virus-mediated autoimmunity: local presentation of CNS antigens and epitope spreading. Ann. N.Y. Acad. Sci. 958 (2002) 26-38
    • (2002) Ann. N.Y. Acad. Sci. , vol.958 , pp. 26-38
    • Tompkins, S.M.1    Fuller, K.G.2    Miller, S.D.3
  • 51
    • 7644231753 scopus 로고    scopus 로고
    • Transition from acute to persistent Theiler's virus infection requires active viral replication that drives proinflammatory cytokine expression and chronic demyelinating disease
    • Trottier M., Schlitt B.P., Kung A.Y., and Lipton H.L. Transition from acute to persistent Theiler's virus infection requires active viral replication that drives proinflammatory cytokine expression and chronic demyelinating disease. J. Virol. 78 (2004) 12480-12488
    • (2004) J. Virol. , vol.78 , pp. 12480-12488
    • Trottier, M.1    Schlitt, B.P.2    Kung, A.Y.3    Lipton, H.L.4
  • 52
    • 0033867980 scopus 로고    scopus 로고
    • A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo
    • Tsai E.Y., Falvo J.V., Tsytsykova A.V., Barczak A.K., Reimold A.M., Glimcher L.H., Fenton M.J., Gordon D.C., Dunn I.F., and Goldfeld A.E. A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo. Mol. Cell. Biol. 20 (2000) 6084-6094
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 6084-6094
    • Tsai, E.Y.1    Falvo, J.V.2    Tsytsykova, A.V.3    Barczak, A.K.4    Reimold, A.M.5    Glimcher, L.H.6    Fenton, M.J.7    Gordon, D.C.8    Dunn, I.F.9    Goldfeld, A.E.10
  • 53
    • 27644594125 scopus 로고    scopus 로고
    • Matrix Metalloproteinases and their inhibitors in the developing mouse brain and spinal cord: a reverse transcription quantitative polymerase chain reaction study
    • Ulrich R., Gerhauser I., Seeliger F., Baumgärtner W., and Alldinger S. Matrix Metalloproteinases and their inhibitors in the developing mouse brain and spinal cord: a reverse transcription quantitative polymerase chain reaction study. Dev. Neurosci. 27 (2005) 408-417
    • (2005) Dev. Neurosci. , vol.27 , pp. 408-417
    • Ulrich, R.1    Gerhauser, I.2    Seeliger, F.3    Baumgärtner, W.4    Alldinger, S.5
  • 55
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • (Research 0034)
    • Vandesompele J., De Preter K., Pattyn F., Poppe B., Van Roy N., De Paepe A., and Speleman F. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome. Biol. 3 (2002) (Research 0034)
    • (2002) Genome. Biol. , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 56
    • 0038371368 scopus 로고    scopus 로고
    • Tmevpg1, a candidate gene for the control of Theiler's virus persistence, could be implicated in the regulation of gamma interferon
    • Vigneau S., Rohrlich P.S., Brahic M., and Bureau J.F. Tmevpg1, a candidate gene for the control of Theiler's virus persistence, could be implicated in the regulation of gamma interferon. J. Virol. 77 (2003) 5632-5638
    • (2003) J. Virol. , vol.77 , pp. 5632-5638
    • Vigneau, S.1    Rohrlich, P.S.2    Brahic, M.3    Bureau, J.F.4
  • 58
    • 0842349247 scopus 로고    scopus 로고
    • The effects of restraint stress on the neuropathogenesis of Theiler's virus infection II: NK cell function and cytokine levels in acute disease
    • Welsh C.J., Bustamante L., Nayak M., Welsh T.H., Dean D.D., and Meagher M.W. The effects of restraint stress on the neuropathogenesis of Theiler's virus infection II: NK cell function and cytokine levels in acute disease. Brain Behav. Immun. 18 (2004) 166-174
    • (2004) Brain Behav. Immun. , vol.18 , pp. 166-174
    • Welsh, C.J.1    Bustamante, L.2    Nayak, M.3    Welsh, T.H.4    Dean, D.D.5    Meagher, M.W.6
  • 59
    • 0026537055 scopus 로고
    • The c-ets 1 proto-oncogene is a transcription factor expressed in endothelial cells during tumor vascularization and other forms of angiogenesis in man
    • Wernert N., Raes M.B., Lassalle P., Dehouck M.P., Gosselin B., Vandenbunder B., and Stéhelin D. The c-ets 1 proto-oncogene is a transcription factor expressed in endothelial cells during tumor vascularization and other forms of angiogenesis in man. Am. J. Pathol. 140 (1992) 119-127
    • (1992) Am. J. Pathol. , vol.140 , pp. 119-127
    • Wernert, N.1    Raes, M.B.2    Lassalle, P.3    Dehouck, M.P.4    Gosselin, B.5    Vandenbunder, B.6    Stéhelin, D.7
  • 60
    • 0345643514 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in tumor invasion
    • Westermarck J., and Kähäri V.-M. Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J. 13 (1999) 781-792
    • (1999) FASEB J. , vol.13 , pp. 781-792
    • Westermarck, J.1    Kähäri, V.-M.2
  • 61
    • 0345435962 scopus 로고    scopus 로고
    • Identification of CD4+ and CD8+ T cell subsets and B cells in the brain of dogs with spontaneous acute, subacute-, and chronic-demyelinating distemper encephalitis
    • Wünschmann A., Alldinger S., Kremmer E., and Baumgärtner W. Identification of CD4+ and CD8+ T cell subsets and B cells in the brain of dogs with spontaneous acute, subacute-, and chronic-demyelinating distemper encephalitis. Vet. Immunol. Immunopathol. 67 (1999) 101-116
    • (1999) Vet. Immunol. Immunopathol. , vol.67 , pp. 101-116
    • Wünschmann, A.1    Alldinger, S.2    Kremmer, E.3    Baumgärtner, W.4
  • 62
    • 0035975268 scopus 로고    scopus 로고
    • Astrocytes, not microglia, are the main cells responsible for viral persistence in Theiler's murine encephalomyelitis virus infection leading to demyelination
    • Zheng L., Calenoff M.A., and Dal Canto M.C. Astrocytes, not microglia, are the main cells responsible for viral persistence in Theiler's murine encephalomyelitis virus infection leading to demyelination. J. Neuroimmunol. 30 (2001) 256-267
    • (2001) J. Neuroimmunol. , vol.30 , pp. 256-267
    • Zheng, L.1    Calenoff, M.A.2    Dal Canto, M.C.3
  • 63
    • 0034330976 scopus 로고    scopus 로고
    • Increased percentage of "double phenotype" form T lymphocytes in blood of patients with multiple sclerosis
    • Ziaber J., Stopczyk D., Tchorzewski H., Chmielewski H., Baj Z., and Pasnik J. Increased percentage of "double phenotype" form T lymphocytes in blood of patients with multiple sclerosis. Neurol. Neurochir. Pol. 34 (2000) 1137-1143
    • (2000) Neurol. Neurochir. Pol. , vol.34 , pp. 1137-1143
    • Ziaber, J.1    Stopczyk, D.2    Tchorzewski, H.3    Chmielewski, H.4    Baj, Z.5    Pasnik, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.