Does aluminum contribute to Alzheimer disease directly, indirectly, or at all?

Journal of Alzheimer's Disease

Volumn 11, Issue 4, 2007, Pages 431-432

  Takashima, Akihiko ^a  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM; AMYLOID BETA PROTEIN; TAU PROTEIN;

AGING; ALZHEIMER DISEASE; BIOCHEMISTRY; BRAIN; CELL LINE; HISTOCHEMISTRY; IN VITRO STUDY; NONHUMAN; NOTE; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION;

EID: 34447645286     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2007-11403     Document Type: Note

References (15)

1. Bharathi, N.M. Shamasundar, T.S. Sathyanarayana Rao, M. Dhanunjaya Naidu, R. Ravid and K.S. Rao, A new insight on Al-maltolate-treated aged rabbit as Alzheimer's animal model, Brain Res Rev 52 (2006), 275-292.
2. H. Braak and E. Braak, Frequency of stages of Alzheimer-related lesions in different age categories, Neurobiol Aging 18 (1997), 351-357.
3. D. Dahl, B.T. Nguyen and A. Bignami, Ultrastructural localization of neurofilament proteins in aluminum-induced neurofibrillary tangles and rat cerebellum by immunoperoxidase labeling, Dev Neurosci 5 (1982), 54-63.
4. D. Games, D. Adams, R. Alessandrini, R. Barbour, P. Berthelette, C. Blackwell, T. Carr, J. Clemens, T. Donaldson, F. Gillespie et al., Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein, Nature 373 (1995), 523-527.
5. J. Gotz, F. Chen, J. van Dorpe and R.M. Nitsch, Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils, Science 293 (2001), 1491-1495.
6. J. Lewis, E. McGowan, J. Rockwood, H. Melrose, P. Nacharaju, M. Van Slegtenhorst, K. Gwinn-Hardy, M. Paul Murphy, M. Baker, X. Yu, K. Duff, J. Hardy, A. Corral, W.L. Lin, S.H. Yen, D.W. Dickson, P. Davies and M. Hutton, Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein, Nat Genet 25 (2000), 402-405.
7. J. Lewis, D.W. Dickson, W.L. Lin, L. Chisholm, A. Corral, G. Jones, S.H. Yen, N. Sahara, L. Skipper, D. Yager, C. Eckman, J. Hardy, M. Hutton and E. McGowan, Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP, Science 293 (2001), 1487-1491.
8. T. Mizoroki, S. Meshitsuka, S. Maeda, M. Murayama, N. Sahara and A. Takashima, Aluminum induces tau aggregation in vitro but not in vivo, J Alzheimers Dis 11 (2007), in press.
9. S. Oddo, A. Caccamo, M. Kitazawa, B.P. Tseng and F.M. LaFerla, Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease, Neurobiol Aging 24 (2003), 1063-1070.
10. D. Pratico, K. Uryu, S. Sung, S. Tang, J.Q. Trojanowski and V.M. Lee, Aluminum modulates brain amyloidosis through oxidative stress in APP transgenic mice, Faseb J 16 (2002), 1138-1140.
11. J. Savory and O. Ghribi, Commentary: Can studies of aluminum toxicity in vivo and in vitro provide relevant information on the pathogenesis and etiology of Alzheimer's disease? J Alzheimers Dis 11 (2007), in press.
12. D.J. Selkoe, R.K. Liem, S.H. Yen and M.L. Shelanski, Biochemical and immunological characterization of neurofilaments in experimental neurofibrillary degeneration induced by aluminum, Brain Res 163 (1979), 235-252.
13. A. Takashima, GSK-3 is essential in the pathogenesis of Alzheimer's disease, J Alzheimers Dis 9 (2006), 309-317.
14. K. Tanemura, T. Akagi, M. Murayama, N. Kikuchi, O. Murayama, T. Hashikawa, Y. Yoshiike, J.M. Park, K. Matsuda, S. Nakao, X. Sun, S. Sato, H. Yamaguchi and A. Takashima, Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau, Neurobiol Dis 8 (2001), 1036-1045.
15. Y. Tatebayashi, T. Miyasaka, D.H. Chui, T. Akagi, K. Mishima, K. Iwasaki, M. Fujiwara, K. Tanemura, M. Murayama, K. Ishiguro, E. Planel, S. Sato, T. Hashikawa and A. Takashima, Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau, Proc Natl Acad Sci USA 99 (2002), 13896-13901.