A dose escalation study of YM150, an oral direct factor Xa inhibitor, in the prevention of venous thromboembolism in elective primary hip replacement surgery

Journal of Thrombosis and Haemostasis

Volumn 5, Issue 8, 2007, Pages 1660-1665

  Eriksson, Bengt I ^a   Turpie, A G G ^b   Lassen, M R ^c   Prins, M H ^d   Agnelli, G ^e   Kalebo P ^a   Gaillard, M L ^f   Meems, L ^f  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b HAMILTON GENERAL HOSPITAL   (Canada)

^c Hoersholm Hospital   (Denmark)

^d MAASTRICHT UNIVERSITY   (Netherlands)

^e UNIVERSITY OF PERUGIA   (Italy)

^f Astellas Pharma Global Development   (Netherlands)

Author keywords

Direct factor Xa inhibitor; Oral anticoagulant; Prophylaxis; Total hip replacement; Venous thromboembolism; YM150

Indexed keywords

BLOOD CLOTTING FACTOR 10A INHIBITOR; ENOXAPARIN; UNCLASSIFIED DRUG; YM 150;

ADULT; AGED; ARTHRALGIA; ARTICLE; CHOLECYSTITIS; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DEHYDRATION; DOSE RESPONSE; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; EPISTAXIS; FEMALE; FEVER; HEMATEMESIS; HEMATOMA; HUMAN; INCIDENCE; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; NERVE INJURY; OPEN STUDY; PERIPHERAL EDEMA; PERONEUS NERVE; PHLEBOGRAPHY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEROMA; SIDE EFFECT; SINGLE BLIND PROCEDURE; SYNCOPE; TOTAL HIP PROSTHESIS; VENOUS THROMBOEMBOLISM; VOMITING; WOUND FLUID; WOUND HEMORRHAGE; WOUND INFECTION;

ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; ANTITHROMBIN III; ARTHROPLASTY, REPLACEMENT, HIP; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; ENOXAPARIN; FEMALE; HUMANS; MALE; MIDDLE AGED; TREATMENT OUTCOME; VENOUS THROMBOSIS;

EID: 34447639584     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2007.02644.x     Document Type: Article

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