Polymorphism of delta-aminolevulinic acid dehydratase and its effect on blood lead levels in thai workers

Archives of Environmental and Occupational Health

Volumn 61, Issue 2, 2006, Pages 67-72

  Wananukul, Winai ^a   Sura, Thanyachai ^a   Salaitanawatwong, Porntip ^b  

^a MAHIDOL UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Adults; Chemical exposure; Heavy metal exposure; Lead poisoning; Occupational diseases; Workers

Indexed keywords

PORPHOBILINOGEN SYNTHASE;

ADULT; ARTICLE; CONTROLLED STUDY; COVARIANCE; DEMOGRAPHY; ETHNIC DIFFERENCE; GENE FREQUENCY; GENOTYPE; HUMAN; LEAD BLOOD LEVEL; MAJOR CLINICAL STUDY; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL;

EID: 34447628674     PISSN: 19338244     EISSN: 21544700     Source Type: Journal    
DOI: 10.3200/AEOH.61.2.67-72     Document Type: Article

References (34)

1. Potluri VR, Astrin KH, Wetmur JG, Bishop DF, Desnick RJ. Human delta-aminolevulinate dehydratase:chromosomal localization to 9q34 by in situ hybridization. Hum Genet. 1987;76:236-239.
2. Kaya AH, Plewinska M, Wong DM, Desnick RJ, Wetmur JG. Human delta-aminolevulinate dehydratase (ALAD) gene:structure and alternative splicing of the erythroid and housekeeping mRNAs. Genomics. 1994;19:242-248.
3. Wetmur JG, Kaya AH, Plewinska M, Desnick RJ. Molecular characterization of the human delta-aminolevulinate dehydratase 2 (ALAD2) allele:implications for molecular screening of individuals for genetic susceptibility to lead poisoning. Am J Hum Genet. 1991;49:757-763.
4. Wetmur JG, Lehnert G, Desnick RJ. The delta-aminolevulinate dehydratase polymorphism:higher blood lead levels in lead workers and environmentally exposed children with the 1-2 and 2-2 isozymes. Environ Res. 1991;56:109-119.
5. Battistuzzi G, Petrucci R, Silvagni L, Urbani FR, Caiola S. Delta-aminolevulinate dehydrase:a new genetic polymorphism in man. Ann Hum Genet. 1981;45:223-229.
6. Kelada SN, Shelton E, Kaufmann RB, Khoury MJ. Delta-aminolevulinic acid dehydratase genotype and lead toxicity:a HuGE review. Am J Epidemiol. 2001;154:1-13.
7. Fleming DE, Chettle DR, Wetmur JG, et al. Effect of the delta-aminolevulinate dehydratase polymorphism on the accumulation of lead in bone and blood in lead smelter workers. Environ Res. 1998;77:49-61.
8. Shen XM, Wu SH, Yan CH, et al. Delta-aminolevulinate dehydratase polymorphism and blood lead levels in Chinese children. Environ Res. 2001;85:185-190.
9. Pumala K, Wananukul W, Naiwatanakul T, Koajarern S. Lead level profile in workers at a battery factory:an eleven year study. Ramathibodi Med J. 1995;18:196-201.
10. Saiki RK, Gelfand DH, Stoffel S, et al. Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science. 1988;239:487-491.
11. Subramanian KS, Meranger JC. A rapid electrothermal atomic absorption spectrophotometric method for cadmium and lead in human whole blood. Clinical Chem. 1981;27:1866-1871.
12. Astrin KH, Bishop DF, Wetmur JG, Kaul B, Davidow B, Desnick RJ. Delta-aminolevulinic acid dehydratase isozymes and lead toxicity. Ann NY Acad Sci. 1987;514:23-29.
13. Suzen HS, Duydu Y, Aydin A. Molecular analysis of delta-aminolevulinic acid dehydratase (ALAD) gene polymorphism in a Turkish population. Biochem Genet. 2004;42:461-467.
14. Duydu Y, Suzen HS. Influence of delta-aminolevulinic acid dehydratase (ALAD) polymorphism on the frequency of sister chromatid exchange (SCE) and the number of high-frequency cells (HFCs) in lymphocytes from lead-exposed workers. Mutat Res. 2003;540:79-88.
15. Chia SE, Yap E, Chia KS. Delta-aminolevulinic acid dehydratase (ALAD) polymorphism and susceptibility of workers exposed to inorganic lead and its effects on neurobehavioral functions. Neurotoxicology. 2004;25:1041-1047.
16. Sakai T. Biomarkers of lead exposure. Ind Health. 2000;38:127-142.
17. Alexander BH, Checkoway H, Costa-Mallen P, et al. Interaction of blood lead and delta-aminolevulinic acid dehydratase genotype on markers of heme synthesis and sperm production in lead smelter workers. Environ Health Perspect. 1998;106:213-216.
18. Lee BK, Lee GS, Stewart WF, et al. Associations of blood pressure and hypertension with lead dose measures and polymorphisms in the vitamin D receptor and delta-aminolevulinic acid dehydratase genes. Environ Health Perspect. 2001;109:383-389.
19. Hsieh LL, Liou SH, Chen YH, Tsai LC, Yang T, Wu TN. Association between aminolevulinate dehydrogenase genotype and blood lead levels in Taiwan. J Occup Environ Med. 2000;42:151-155.
20. Ben-Ezzer J, Oelsner H, Szeinberg A. Genetic polymorphism of delta-aminolevulinate dehydrase in several population groups in Israel. Hum Hered. 1987;37:229-232.
21. Benkmann HG, Bogdanski P, Goedde HW. Polymorphism of delta-aminolevulinic acid dehydratase in various populations. Hum Hered. 1983;33:62-64.
22. Scheil HG, Scheffrahn W. Gene frequencies of the enzymes ALADH, GOT2, GPT, PGM3, SAHH and UMPK in a Swiss population. Anthropol Anz. 1987;45:255-260.
23. Petrucci R, Leonardi A, Battistuzzi G. The genetic polymorphism of delta-aminolevulinate dehydrase in Italy. Hum Genet. 1982;60:289-290.
24. Amorim A, Rocha J, Santos MT. Distribution of ACP1, AK1 and ALAD polymorphisms in northern Portugal. Gene Geogr. 1994;8:147-150.
25. Caeiro B, Rey D. Genetic heterogeneity of delta-aminolevulinate dehydrase and phosphoglycolate phosphatase in north-west Spain. Hum Hered. 1985;35:21-24.
26. Garcia-Orad A, Aguirre AI, Mazon LI, de Pancorbo MM. Polymorphism of delta-aminolevulinic acid dehydratase in Basque populations. Hum Hered. 1987;37:321-322.
27. Smith CM, Wang X, Hu H, Kelsey KT. A polymorphism in the delta-aminolevulinic acid dehydratase gene may modify the pharmacokinetics and toxicity of lead. Environ Health Perspect. 1995;103:248-253.
28. Juli E, Scheil HG, Gunther A. Gene frequency of delta-aminolevulinate dehydratase (E.C. 4.2.1.24) in a West German population. Anthropol Anz. 1983;41:309-311.
29. Eiberg H, Mohr J, Nielsen LS. Delta-aminolevulinate dehydrase:synteny with ABO-AK1-ORM (and assignment to chromosome 9). Clin Genet. 1983;23:150-154.
30. Raczek E. Polymorphism of delta-aminolevulinate dehydratase in the upper Silesian population, Poland. Hum Hered. 1994;44:172-174.
31. Kapotis C, Tsomi A, Babionitakis A, et al. The genetic polymorphism of aminolevulinate dehydratase (ALADH) in Greece. Hum Hered. 1998;48:155-157.
32. Goedde HW, Rothhammer F, Benkmann HG, Bogdanski P. Ecogenetic studies in Atacameno Indians. Hum Genet. 1984;67:343-346.
33. Pumala K, Viriyanondtha S. Time course of lead accumulation in battery workers. Ramathibodi Med J. 1994;17:11-15.
34. Wu MT, Kelsey K, Schwartz J, Sparrow D, Weiss S, Hu H. A delta-aminolevulinic acid dehydratase (ALAD) polymorphism may modify the relationship of low-level lead exposure to uricemia and renal function:the normative aging study. Environ Health Perspect. 2003;111:335-341.