Enhanced activity of strobilurin and fludioxonil by using berberine and phenolic compounds to target fungal antioxidative stress response

Letters in Applied Microbiology

Volumn 45, Issue 2, 2007, Pages 134-141

  Kim, J H ^a   Campbell, B C ^a   Mahoney, N ^a   Chan, K L ^a   Molyneux, R J ^a   May, G S ^b  

^a WESTERN REGIONAL RESEARCH CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Alkaloid; Antifungal; Antioxidative stress system; Aspergillus; Penicillium; Phenolics; Saccharomyces cerevisiae

Indexed keywords

ALKALOIDS; METABOLITES; PHENOLS; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TOXICITY; YEAST;

ANTI-OXIDATIVE STRESS SYSTEM; ANTIFUNGALS; FLUDIOXONIL; MITOCHONDRIAL SUPEROXIDE; MITOGEN-ACTIVATED PROTEIN KINASE; PENICILLIUM; PHENOLICS; STROBILURINS; SUPER OXIDE DISMUTASE; SUPEROXIDE DISMUTASES;

ASPERGILLUS;

ALDEHYDE DERIVATIVE; ALKALOID; ANTIOXIDANT; BERBERINE; FLUDIOXONIL; FUNGICIDE; MITOGEN ACTIVATED PROTEIN KINASE; NATURAL PRODUCT; PHENOL DERIVATIVE; STROBILURIN; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG;

GENES; GENETIC ENGINEERING; PHENOLS; SIGNAL TRANSDUCTION; TOXICITY; YEAST;

ALKALOID; ANTIMICROBIAL ACTIVITY; ANTIOXIDANT; FUNGICIDE; FUNGUS; INTEGRATED APPROACH; PESTICIDE RESISTANCE; PHENOLIC COMPOUND; TOXICITY TEST;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS; ASPERGILLUS FUMIGATUS; CELLULAR STRESS RESPONSE; FUNGAL VIRULENCE; GENE DELETION; MITOCHONDRIAL RESPIRATION; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PENICILLIUM EXPANSUM; PHENOTYPE; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; STRESS;

ASPERGILLUS; ASPERGILLUS FUMIGATUS; FUNGI; PENICILLIUM; PENICILLIUM EXPANSUM; SACCHAROMYCES CEREVISIAE;

EID: 34447625862     PISSN: 02668254     EISSN: 1472765X     Source Type: Journal    
DOI: 10.1111/j.1472-765X.2007.02159.x     Document Type: Article

References (33)

1. Beekrum, S., Govinden, R., Padayachee, T. Odhav, B. (2003) Naturally occurring phenols: A detoxification strategy for fumonisin B1. Food Addit Contam 20, 490 493.
2. Boy-Marcotte, E., Perrot, M., Bussereau, F., Boucherie, H. Jacquet, M. (1998) Msn2p and Msn4p control a large number of genes induced at the diauxic transition which are repressed by cyclic AMP in Saccharomyces cerevisiae. J Bacteriol 180, 1044 1052.
3. Cos, P., Vlietinck, A.J., Berghe, D.V. Maes, L. (2006) Anti-infective potential of natural products: how to develop a stronger in vitro 'proof-of-concept'. J Ethnopharmacol 106, 290 302.
4. D'Auria, F.D., Tecca, M., Strippoli, R. Simonetti, N. (2001) In vitro activity of propyl gallate-azole drug combination against fluconazole- and itraconazole-resistant Candida albicans strains. Lett Appl Microbiol 32, 220 223.
5. Demasi, A.P.D., Pereira, G.A.G. Netto, L.E.S. (2001) Cytosolic thioredoxin peroxidase I is essential for the antioxidant defense of yeast with dysfunctional mitochondria. FEBS Lett 509, 430 434.
6. Florianowicz, T. (1998) Penicillium expansum growth and production of patulin in the presence of benzoic acid and its derivatives. Acta Microbiol Pol 47, 45 53.
7. Furukawa, K., Hoshi, Y., Maeda, T., Nakajima, T. Abe, K. (2005) Aspergillus nidulans HOG pathway is activated only by two-component signalling pathway in response to osmotic stress. Mol Microbiol 56, 1246 1261.
8. Guillen, F. Evans, C.S. (1994) Anisaldehyde and veratraldehyde acting as redox cycling agents for H2O2 production by Pleurotus eryngii. Appl Environ Microbiol 60, 2811 2817.
9. Hnatova, M., Gbelska, Y., Obernauerova, M., Subikova, V. Subik, J. (2003) Cross-resistance to strobilurin fungicides in mitochondrial and nuclear mutants of Saccharomyces cerevisiae. Folia Microbiol (Praha) 48, 496 500.
10. Jaeger, T. Flohe, L. (2006) The thiol-based redox networks of pathogens: unexploited targets in the search for new drugs. Biofactors 27, 109 120.
11. Jang, M.J., Jwa, M., Kim, J.H. Song, K. (2002) Selective inhibition of MAPKK Wis1 in the stress-activated MAPK cascade of Schizosaccharomyces pombe by novel berberine derivatives. J Biol Chem 277, 12388 12395.
12. Kim, J.H., Campbell, B.C., Yu, J., Mahoney, N., Chan, K.L., Molyneux, R.J., Bhatnagar, D. Cleveland, T.E. (2005) Examination of fungal stress response genes using Saccharomyces cerevisiae as a model system: targeting genes affecting aflatoxin biosynthesis by Aspergillus flavus link. Appl Microbiol Biotechnol 67, 807 815.
13. Kim, J.H., Campbell, B.C., Mahoney, N., Chan, K.L., Molyneux, R.J. May, G.S. (2006a) Targeting signal transduction and oxidative stress response pathways: control of pathogenic Aspergillus with phenolics that inhibit the mitochondrial function. J Appl Microbiol 101, 181 189.
14. Kim, J.H., Mahoney, N., Chan, K.L., Molyneux, R.J. Campbell, B.C. (2006b) Controlling food-contaminating fungi by targeting their antioxidative stress-response system with natural phenolic compounds. Appl Microbiol Biotechnol 70, 735 739.
15. Kim, J.H., Campbell, B.C., Chan, K.L. May, G.S. (2006c) Targeting mitochondrial respiratory and oxidative stress response systems for control of aspergilli. In Eigth European Conference on Fungal Genetics/Third Aspergillus Meeting. eds. Druzhinina, I.S., Kopchinskiy, A.G. Kubicek, C.P. p. 318 Vienna, Austria : Vienna University of Technology. 8-11 April.
16. Kojima, K., Takano, Y., Yoshimi, A., Tanaka, C., Kikuchi, T. Okuno, T. (2004) Fungicide activity through activation of a fungal signalling pathway. Mol Microbiol 53, 1785 1796.
17. Kojima, K., Bahn, Y.S. Heitman, J. (2006) Calcineurin, Mpk1 and Hog1 MAPK pathways independently control fludioxonil antifungal sensitivity in Cryptococcus neoformans. Microbiol 152, 591 604.
18. Krantz, M., Becit, E. Hohmann, S. (2006) Comparative genomics of the HOG-signalling system in fungi. Curr Genet 49, 137 151.
19. Ochiai, N., Fujimura, M., Oshima, M., Motoyama, T., Ichiishi, A., Yamada-Okabe, H. Yamaguchi, I. (2002) Effects of iprodione and fludioxonil on glycerol synthesis and hyphal development in Candida albicans. Biosci Biotechnol Biochem 66, 2209 2215.
20. Parsons, A.B., Brost, R.L., Ding, H., Li, Z., Zhang, C., Sheikh, B., Brown, G.W., Kane, P.M. et al. (2004) Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nat Biotechnol 22, 62 69.
21. Pauli, A. (2006) Anticandidal low molecular compounds from higher plants with special reference to compounds from essential oils. Med Res Rev 26, 223 268.
22. Quan, H., Cao, Y.Y., Xu, Z., Zhao, J.X., Gao, P.H., Qin, X.F. Jiang, Y.Y. (2006) Potent in vitro synergism of fluconazole and berberine chloride against clinical isolates of Candida albicans resistant to fluconazole. Antimicrob Agents Chemother 50, 1096 1099.
23. Reyes, G., Romans, A., Nguyen, C.K. May, G.S. (2006) The MAP kinase MpkC of Aspergillus fumigatus is required for utilization of sorbitol (Vp-29). In Eigth European Conference on Fungal Genetics/Third Aspergillus Meeting. eds. Druzhinina, I.S., Kopchinskiy, A.G. Kubicek, C.P. p. 318 Vienna, Austria : Vienna University of Technology, 8-11 April.
24. Rosslenbroich, H.-J. Steubler, D. (2000) Botrytis cinerea- history of chemical control and novel fungicides for its management. Crop Prot 19, 557 561.
25. Shvedova, A.A., Kommineni, C., Jeffries, B.A., Castranova, V., Tyurina, Y.Y., Tyurin, V.A., Serbinova, E.A., Fabisiak, J.P. et al. (2000) Redox cycling of phenol induces oxidative stress in human epidermal keratinocytes. J Invest Dermatol 114, 354 364.
26. Slater, E.C. (1973) The mechanism of action of the respiratory inhibitor, antimycin. Biochim Biophys Acta 301, 129 154.
27. Smits, G.J. Brul, S. (2005) Stress tolerance in fungi - to kill a spoilage yeast. Curr Opin Biotechnol 16, 225 230.
28. Stermitz, F.R., Lorenz, P., Tawara, J.N., Zenewicz, L.A. Lewis, K. (2000) Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor. Proc Natl Acad Sci USA 97, 1433 1437.
29. Tawata, S., Taira, S., Kobamoto, N., Zhu, J., Ishihara, M. Toyama, S. (1996) Synthesis and antifungal activity of cinnamic acid esters. Biosci Biotechnol Biochem 60, 909 910.
30. Wu, L.T., Tsou, M.F., Ho, C.C., Chuang, J.Y., Kuo, H.M. Chung, J.G. (2005) Berberine inhibits arylamine N-acetyltransferase activity and gene expression in Salmonella Typhi. Curr Microbiol 51, 255 261.
31. Xue, T., Nguyen, C.K., Romans, A. May, G.S. (2004) A mitogen-activated protein kinase that senses nitrogen regulates conidial germination and growth in Aspergillus fumigatus. Eukaryot Cell 3, 557 560.
32. Yu, H.H., Kim, K.J., Cha, J.D., Kim, H.K., Lee, Y.E., Choi, N.Y. You, Y.O. (2005) Antimicrobial activity of berberine alone and in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus. J Med Food 8, 454 461.
33. Zheng, D., Olaya, G. Koller, W. (2000) Characterization of laboratory mutants of Venturia inaequalis resistant to the strobilurin-related fungicide kresoxim-methyl. Curr Genet 38, 148 155.