Changes in fibrinogen and fibrin induced by a peptide analog of fibrinogen γ365-380

Journal of Thrombosis and Haemostasis

Volumn 5, Issue 8, 2007, Pages 1707-1714

  Dempfle, Carl Erik ^a   Bindeballe, N ^a   Munchbach M ^a   Blume, C ^a   Borggrefe, M ^a   Mosesson, M W ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b BLOOD RESEARCH INSTITUTE   (United States)

Author keywords

Brinogen; Fibrin; Peptides; Polymerization

Indexed keywords

FIBRIN; FIBRINOGEN; FIBRINOGEN GAMMA[365-380]; PEPTIDE DERIVATIVE; PLASMIN; TETRAMER; THROMBIN; TRYPTOPHAN; UNCLASSIFIED DRUG;

ARTICLE; BLOOD CLOTTING TIME; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ELASTICITY; FIBER; HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; SCANNING ELECTRON MICROSCOPY; THROMBOCYTE AGGREGATION; THROMBOELASTOGRAPHY; TRANSMISSION ELECTRON MICROSCOPY; TURBIDITY;

AMINO ACIDS; BLOOD PLATELETS; CROSS-LINKING REAGENTS; FIBRIN; FIBRINOGEN; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; PEPTIDES; PLATELET AGGREGATION; POLYMERS; THROMBELASTOGRAPHY; THROMBIN; TIME FACTORS;

EID: 34447623198     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2007.02633.x     Document Type: Article

References (28)

1. Mosesson MW. Fibrinogen and fibrin polymerization: Appraisal of the binding events that accompany fibrin generation and fibrin clot assembly. Blood Coagul Fibrinolysis 1997; 8: 257-67.
2. Kirschbaum NE, Mosesson MW, Amrani DL. Characterization of the gamma chain platelet binding site on fibrinogen fragment D. Blood 1992; 79: 2643-8.
3. Mosesson MW, Siebenlist KR, Amrani DL, DiOrio JP. Identification of covalently linked trimeric and tetrameric D domains in crosslinked fibrin. Proc Natl Acad Sci USA 1989; 86: 1113-7.
4. Laudano AP, Doolittle RF. Studies on synthetic peptides that bind to fibrinogen and prevent fibrin polymerization. Structural requirements, number of binding sites, and species differences. Biochemistry 1980; 19: 1013-9.
5. Laudano AP, Doolittle RF. Synthetic peptide derivatives that bind to fibrinogen and prevent the polymerization of fibrin monomers. Proc Natl Acad Sci USA 1978; 75: 3085-9.
6. Gartner TK, Loudon R, Taylor DB. The peptides APLHK, EHIPA and GAPL are hydropathically equivalent peptide mimics of a fibrinogen binding domain of glycoprotein IIb/IIIa. Biochem Biophys Res Commun 1991; 180: 1446-52.
7. Tribbick G. Multipin peptide libraries for antibody and receptor epitope screening and characterization. J Immunol Methods 2002; 267: 27-35.
8. Hartert H. Thrombelastography, a method for physical analysis of blood coagulation.. Z Gesamte Exp Med 1951; 117: 189-203.
9. Carr ME Jr, Zekert SL. Measurement of platelet-mediated force development during plasma clot formation. Am J Med Sci 1991; 302: 13-8.
10. Carr ME Jr, Martin EJ, Carr SL. Delayed, reduced or inhibited thrombin production reduces platelet contractile force and results in weaker clot formation. Blood Coagul Fibrinolysis 2002; 13: 193-7.
11. Siebenlist KR, Mosesson MW. Evidence of intramolecular cross-linked A alpha.gamma chain heterodimers in plasma fibrinogen. Biochemistry 1996; 35: 5817-21.
12. Lorand L, Chou CH, Simpson I. Thiolester substrates for transamidating enzymes: Studies on fibrinoligase. Proc Natl Acad Sci USA 1972; 69: 2645-8.
13. Dempfle CE, Harenberg J, Hochreuter K, Heene DL. Microtiter assay for measurement of factor XIII activity in plasma. J Lab Clin Med 1992; 119: 522-8.
14. Mosesson MW, Siebenlist KR, DiOrio JP, Matsuda M, Hainfeld JF, Wall JS. The role of fibrinogen D domain intermolecular association sites in the polymerization of fibrin and fibrinogen Tokyo II (gamma 275 Arg->Cys). J Clin Invest 1995; 96: 1053-8.
15. Brennan SO, Wyatt JM, May S, De Caigney S, George PM. Hypofibrinogenemia due to novel 316 Asp -> Tyr substitution in the fibrinogen Bbeta chain. Thromb Haemost 2001; 85: 450-3.
16. Rubbia-Brandt L, Neerman-Arbez M, Rougemont AL, Male PJ, Spahr L. Fibrinogen gamma375 arg->trp mutation (fibrinogen aguadilla) causes hereditary hypofibrinogenemia, hepatic endoplasmic reticulum storage disease and cirrhosis. Am J Surg Pathol 2006; 30: 906-11.
17. Francalanci P, Santorelli FM, Talini I, Boldrini R, Devito R, Camassei FD, Maggiore G, Callea F. Severe liver disease in early childhood due to fibrinogen storage and de novo gamma375Arg->Trp gene mutation. J Pediatr 2006; 148: 396-8.
18. Brennan SO, Maghzal G, Shneider BL, Gordon R, Magid MS, George PM. Novel fibrinogen gamma375 Arg->Trp mutation (fibrinogen aguadilla) causes hepatic endoplasmic reticulum storage and hypofibrinogenemia. Hepatology 2002; 36: 652-8.
19. Yoshida N, Hirata H, Morigami Y, Imaoka S, Matsuda M, Yamazumi K, Asakura S. Characterization of an abnormal fibrinogen Osaka V with the replacement of gamma-arginine 375 by glycine. The lack of high affinity calcium binding to D-domains and the lack of protective effect of calcium on fibrinolysis. J Biol Chem 1992; 267: 2753-9.
20. Okumura N, Gorkun OV, Lord ST. Severely impaired polymerization of recombinant fibrinogen gamma-364 Asp -> His, the substitution discovered in a heterozygous individual. J Biol Chem 1997; 272: 29596-601.
21. Okumura N, Furihata K, Terasawa F, Nakagoshi R, Ueno I, Katsuyama T. Fibrinogen Matsumoto I: A gamma 364 Asp->His (GAT->CAT) substitution associated with defective fibrin polymerization. Thromb Haemost 1996; 75: 887-91.
22. Podolnikova NP, Yakubenko VP, Volkov GL, Plow EF, Ugarova TP. Identification of a novel binding site for platelet integrins alpha IIb beta 3 (GPIIbIIIa) and alpha 5 beta 1 in the gamma C-domain of fibrinogen. J Biol Chem 2003; 278: 32251-8.
23. Podolnikova NP, Gorkun OV, Loreth RM, Yee VC, Lord ST, Ugarova TP. A cluster of basic amino acid residues in the gamma370-381 sequence of fibrinogen comprises a binding site for platelet integrin alpha(IIb)beta3 (glycoprotein IIb/IIIa). Biochemistry 2005; 44: 16920-30.
24. Zamarron C, Ginsberg MH, Plow EF. Monoclonal antibodies specific for a conformationally altered state of fibrinogen. Thromb Haemost 1990; 64: 41-6.
25. Lishko VK, Kudryk B, Yakubenko VP, Yee VC, Ugarova TP. Regulated unmasking of the cryptic binding site for integrin alpha M beta 2 in the gamma C-domain of fibrinogen. Biochemistry 2002; 41: 12942-51.
26. Southan C, Thompson E, Panico M, Etienne T, Morris HR, Lane DA. Characterization of peptides cleaved by plasmin from the C-terminal polymerization domain of human fibrinogen. J Biol Chem 1985; 260: 13095-101.
27. Marx G, Ben-Moshe M, Magdassi S, Gorodetsky R. Fibrinogen C-terminal peptidic sequences (Haptides) modulate fibrin polymerization. Thromb Haemost 2004; 91: 43-51.
28. Gorkun OV, Litvinov RI, Veklich YI, Weisel JW. Interactions mediated by the N-terminus of fibrinogen's Bbeta chain. Biochemistry 2006; 45: 14843-52.