The carcinogen safrole increases intracellular free Ca 2+ levels and causes death in MDCK cells

Chinese Journal of Physiology

Volumn 50, Issue 1, 2007, Pages 34-40

  Chen, Wei Chuan ^a   Cheng, He Hsiung ^b   Huang, Chun Jen ^c,d   Lu, Yih Chau ^e   Chen, I Shu ^e   Liu, Shiuh Inn ^e   Hsu, Shu Shong ^e   Chang, Hong Tai ^e   Huang, Jong Khing ^e   Chen, Jin Shyr ^e   Jan, Chung Ren ^e  

^a PINGTUNG CHRISTIAN HOSPITAL   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d TIAN SHENG MEMORIAL HOSPITAL   (Taiwan)

^e KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Ca 2+; Ca 2+ stores; Fura 2; MDCK; Renal tubular cells; Safrole

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIUM ION; DILTIAZEM; FURA 2; NIFEDIPINE; PHOSPHOLIPASE C; SAFROLE; THAPSIGARGIN; TRYPAN BLUE; VERAPAMIL; 1 (6 ((3 METHOXYESTRA 1,3,5(10) TRIEN 17 YL)AMINO)HEXYL) 1H PYRROLE 2,5 DIONE; 1-(6-((3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL)-1H-PYRROLE-2,5-DIONE; 2 PYRROLIDONE DERIVATIVE; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CARCINOGEN; ESTRANE DERIVATIVE; PHOSPHODIESTERASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM DEPLETION; CALCIUM SIGNALING; CALCIUM TRANSPORT; CARCINOGENICITY; CELL DEATH; CELL KILLING; CELL POPULATION; CELL STRAIN; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; ENDOPLASMIC RETICULUM; ENZYME INHIBITION; EXTRACELLULAR CALCIUM; FLUORESCENCE ANALYSIS; KIDNEY TUBULE CELL; NONHUMAN; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; CULTURE MEDIUM; DOG; DRUG ANTAGONISM; DRUG EFFECT; EXTRACELLULAR FLUID; INTRACELLULAR MEMBRANE; KIDNEY; METABOLISM; OSMOLARITY; PHYSIOLOGY;

ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CARCINOGENS; CELL LINE; CELL SURVIVAL; CULTURE MEDIA; CYTOSOL; DOGS; ENDOPLASMIC RETICULUM; ESTRENES; EXTRACELLULAR FLUID; INTRACELLULAR MEMBRANES; KIDNEY; OSMOLAR CONCENTRATION; PHOSPHODIESTERASE INHIBITORS; PHOSPHOLIPASE C; PYRROLIDINONES; SAFROLE; THAPSIGARGIN;

EID: 34447623033     PISSN: 03044920     EISSN: 26660059     Source Type: Journal    
DOI: None     Document Type: Article

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