Pharmacokinetics and safety of intravenously administered citrulline in children undergoing congenital heart surgery: Potential therapy for postoperative pulmonary hypertension

Journal of Thoracic and Cardiovascular Surgery

Volumn 134, Issue 2, 2007, Pages 319-326

  Barr, Frederick E ^a   Tirona, Rommel G ^b   Taylor, Mary B ^a   Rice, Geraldine ^a   Arnold, Judith ^a   Cunningham, Gary ^a   Smith, Heidi A B ^a   Campbell, Adam ^a   Canter, Jeffrey A ^b   Christian, Karla G ^a   Drinkwater, Davis C ^a   Scholl, Frank ^a   Kavanaugh McHugh, Ann ^a   Summar, Marshall L ^b  

^a MONROE CARELL JR CHILDREN S HOSPITAL AT VANDERBILT   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CITRULLINE; NITRIC OXIDE;

ARTICLE; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; COMPLETE HEART BLOCK; CONGENITAL HEART MALFORMATION; CONTINUOUS INFUSION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG DOSE ESCALATION; DRUG HALF LIFE; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; HEART ATRIUM SEPTUM DEFECT; HEART SURGERY; HEART VENTRICLE SEPTUM DEFECT; HUMAN; INFANT; INTENSIVE CARE UNIT; MALE; MEAN ARTERIAL PRESSURE; OPEN STUDY; POSTOPERATIVE CARE; PRIORITY JOURNAL; PULMONARY HYPERTENSION;

CARDIAC SURGICAL PROCEDURES; CHILD; CHILD, PRESCHOOL; CITRULLINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEART DEFECTS, CONGENITAL; HUMANS; HYPERTENSION, PULMONARY; INFANT; INFUSIONS, INTRAVENOUS; INJECTIONS, INTRAVENOUS; MALE; TREATMENT OUTCOME;

EID: 34447617341     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2007.02.043     Document Type: Article

References (11)

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