메뉴 건너뛰기




Volumn 97, Issue 2, 2007, Pages 265-278

Evaluating transport of manganese from olfactory mucosa to striatum by pharmacokinetic modeling

Author keywords

Manganese; Olfactory transport; Pharmacokinetic model

Indexed keywords

CHLORIDE; MANGANESE; MANGANESE CHLORIDE; PHOSPHATE;

EID: 34447567409     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm061     Document Type: Article
Times cited : (45)

References (48)
  • 1
    • 0033064057 scopus 로고    scopus 로고
    • Pharmacokinetic data needs to support risk assessments for inhaled and ingested manganese
    • Andersen, M. E., Gearhart, J. M., and Clewell, H. J., III (1999). Pharmacokinetic data needs to support risk assessments for inhaled and ingested manganese. Neurotoxicology 20, 161-171.
    • (1999) Neurotoxicology , vol.20 , pp. 161-171
    • Andersen, M.E.1    Gearhart, J.M.2    Clewell III, H.J.3
  • 2
    • 3042641182 scopus 로고    scopus 로고
    • In vivo detection of neuroarchitecture in the rodent brain using manganeseenhanced MRI
    • Aoki, I., Wu, Y. J., Silva, A. C., Lynch, R. M., and Koretsky, A. P. (2004). In vivo detection of neuroarchitecture in the rodent brain using manganeseenhanced MRI. Neuroimage 22, 1046-1059.
    • (2004) Neuroimage , vol.22 , pp. 1046-1059
    • Aoki, I.1    Wu, Y.J.2    Silva, A.C.3    Lynch, R.M.4    Koretsky, A.P.5
  • 3
    • 0028366603 scopus 로고
    • Manganese (Mn) transport across the rat blood-brain barrier: Saturable and transferrin-dependent transport mechanisms
    • Aschner, M., and Gannon, M. (1994). Manganese (Mn) transport across the rat blood-brain barrier: Saturable and transferrin-dependent transport mechanisms. Brain Res. Bull. 33, 345-349.
    • (1994) Brain Res. Bull , vol.33 , pp. 345-349
    • Aschner, M.1    Gannon, M.2
  • 4
    • 0742304311 scopus 로고    scopus 로고
    • The potential of nasal application for delivery to the central brain-a microdialysis study of fluorescein in rats
    • Bagger, M. A., and Bechgaard, E. (2004). The potential of nasal application for delivery to the central brain-a microdialysis study of fluorescein in rats. Eur. J. Pharm. Sci. 21, 235-242.
    • (2004) Eur. J. Pharm. Sci , vol.21 , pp. 235-242
    • Bagger, M.A.1    Bechgaard, E.2
  • 5
    • 0034671436 scopus 로고    scopus 로고
    • Direct olfactory transport of inhaled manganese ((54)MnCl(2)) to the rat brain: Toxicokinetic investigations in a unilateral nasal occlusion model
    • Brenneman, K. A., Wong, B. A., Buccellato, M. A., Costa, E. R., Gross, E. A., and Dorman, D. C. (2000). Direct olfactory transport of inhaled manganese ((54)MnCl(2)) to the rat brain: Toxicokinetic investigations in a unilateral nasal occlusion model. Toxicol. Appl. Pharmacol. 169, 238-248.
    • (2000) Toxicol. Appl. Pharmacol , vol.169 , pp. 238-248
    • Brenneman, K.A.1    Wong, B.A.2    Buccellato, M.A.3    Costa, E.R.4    Gross, E.A.5    Dorman, D.C.6
  • 6
    • 0035153334 scopus 로고    scopus 로고
    • Direct nose-brain transport of benzoylecgonine following intranasal administration in rats
    • Chow, H. H., Anavy, N., and Villalobos, A. (2001). Direct nose-brain transport of benzoylecgonine following intranasal administration in rats. J. Pharm. Sci. 90, 1729-1735.
    • (2001) J. Pharm. Sci , vol.90 , pp. 1729-1735
    • Chow, H.H.1    Anavy, N.2    Villalobos, A.3
  • 8
    • 0037234204 scopus 로고    scopus 로고
    • Manganese distribution across the blood-brain barrier. I. Evidence for carrier-mediated influx of managanese citrate as well as manganese and manganese transferrin
    • Crossgrove, J. S., Allen, D. D., Bukaveckas, B. L., Rhineheimer, S. S., and Yokel, R. A. (2003). Manganese distribution across the blood-brain barrier. I. Evidence for carrier-mediated influx of managanese citrate as well as manganese and manganese transferrin. Neurotoxicology 24, 3-13.
    • (2003) Neurotoxicology , vol.24 , pp. 3-13
    • Crossgrove, J.S.1    Allen, D.D.2    Bukaveckas, B.L.3    Rhineheimer, S.S.4    Yokel, R.A.5
  • 9
    • 0031956910 scopus 로고    scopus 로고
    • Methylcyclopentadienyl manganese tricarbonyl: Health risk uncertainties and research directions
    • Davis, J. M. (1998). Methylcyclopentadienyl manganese tricarbonyl: Health risk uncertainties and research directions. Environ. Health Perspect. 106(Suppl 1), 191-201.
    • (1998) Environ. Health Perspect , vol.106 , Issue.SUPPL. 1 , pp. 191-201
    • Davis, J.M.1
  • 10
    • 0033043506 scopus 로고    scopus 로고
    • Inhalation health risks of manganese: An EPA perspective
    • Davis, J. M. (1999). Inhalation health risks of manganese: An EPA perspective. Neurotoxicology 20, 511-518.
    • (1999) Neurotoxicology , vol.20 , pp. 511-518
    • Davis, J.M.1
  • 12
    • 33747253556 scopus 로고    scopus 로고
    • Application of pharmacokinetic data to the risk assessment of inhaled manganese
    • Dorman, D. C., Struve, M. F., Clewell, H. J., III, and Andersen, M. E. (2006). Application of pharmacokinetic data to the risk assessment of inhaled manganese. Neurotoxicology 27, 752-764.
    • (2006) Neurotoxicology , vol.27 , pp. 752-764
    • Dorman, D.C.1    Struve, M.F.2    Clewell III, H.J.3    Andersen, M.E.4
  • 13
    • 0035862914 scopus 로고    scopus 로고
    • Influence of particle solubility on the delivery of inhaled manganese to the rat brain: Manganese sulfate and manganese tetroxide pharmacokinetics following repeated (14-day) exposure
    • Dorman, D. C., Struve, M. F., James, R. A., Marshall, M. W., Parkinson, C. U., and Wong, B. A. (2001a). Influence of particle solubility on the delivery of inhaled manganese to the rat brain: Manganese sulfate and manganese tetroxide pharmacokinetics following repeated (14-day) exposure. Toxicol. Appl. Pharmacol. 170, 79-87.
    • (2001) Toxicol. Appl. Pharmacol , vol.170 , pp. 79-87
    • Dorman, D.C.1    Struve, M.F.2    James, R.A.3    Marshall, M.W.4    Parkinson, C.U.5    Wong, B.A.6
  • 14
    • 0035068627 scopus 로고    scopus 로고
    • Influence of dietary manganese on the pharmacokinetics of inhaled manganese sulfate in male CD rats
    • Dorman, D. C., Struve, M. F., James, R. A.,McManus, B. E.,Marshall,M.W., and Wong, B.A. (2001b). Influence of dietary manganese on the pharmacokinetics of inhaled manganese sulfate in male CD rats. Toxicol. Sci. 60, 242-251.
    • (2001) Toxicol. Sci , vol.60 , pp. 242-251
    • Dorman, D.C.1    Struve, M.F.2    James, R.A.3    McManus, B.E.4    Marshall, M.W.5    Wong, B.A.6
  • 16
    • 0036628679 scopus 로고    scopus 로고
    • The relationship of particle size to olfactory nerve uptake of a non-soluble form of manganese into brain
    • Fechter, L. D., Johnson, D. L., and Lynch, R. A. (2002). The relationship of particle size to olfactory nerve uptake of a non-soluble form of manganese into brain. Neurotoxicology 23, 177-183.
    • (2002) Neurotoxicology , vol.23 , pp. 177-183
    • Fechter, L.D.1    Johnson, D.L.2    Lynch, R.A.3
  • 17
    • 0025216962 scopus 로고
    • Accumulation and turnover of metabolites of toluene and xylene in nasal mucosa and olfactory bulb in the mouse
    • Ghantous, H., Dencker, L., Gabrielsson, J., Danielsson, B. R., and Bergman, K. (1990). Accumulation and turnover of metabolites of toluene and xylene in nasal mucosa and olfactory bulb in the mouse. Pharmacol. Toxicol. 66, 87-92.
    • (1990) Pharmacol. Toxicol , vol.66 , pp. 87-92
    • Ghantous, H.1    Dencker, L.2    Gabrielsson, J.3    Danielsson, B.R.4    Bergman, K.5
  • 18
    • 16844365746 scopus 로고    scopus 로고
    • Pharmacokinetics of substrate uptake and distribution in murine brain after nasal instillation
    • Graff, C. L., Zhao, R., and Pollack, G. M. (2005). Pharmacokinetics of substrate uptake and distribution in murine brain after nasal instillation. Pharm. Res. 22, 235-244.
    • (2005) Pharm. Res , vol.22 , pp. 235-244
    • Graff, C.L.1    Zhao, R.2    Pollack, G.M.3
  • 19
    • 0000906417 scopus 로고
    • Basal ganglia
    • 2nd ed, G. Paxinos, Ed, pp, Academic Press, San Diego, CA
    • Heimer, L., Zahm, D. S., and Alheid, G. F. (1995). Basal ganglia. In: The Rat Nervous System, 2nd ed. (G. Paxinos, Ed.), pp. 579-628. Academic Press, San Diego, CA.
    • (1995) The Rat Nervous System , pp. 579-628
    • Heimer, L.1    Zahm, D.S.2    Alheid, G.F.3
  • 20
    • 0033010669 scopus 로고    scopus 로고
    • Transport of manganese via the olfactory pathway in rats: Dosage dependency of the uptake and subcellular distribution of the metal in the olfactory epithelium and the brain
    • Henriksson, J., Tallkvist, J., and Tjälve, H. (1999). Transport of manganese via the olfactory pathway in rats: Dosage dependency of the uptake and subcellular distribution of the metal in the olfactory epithelium and the brain. Toxicol. Appl. Pharmacol. 156, 119-128.
    • (1999) Toxicol. Appl. Pharmacol , vol.156 , pp. 119-128
    • Henriksson, J.1    Tallkvist, J.2    Tjälve, H.3
  • 22
    • 0034095651 scopus 로고    scopus 로고
    • Transport of drugs from the nasal cavity to the central nervous system
    • Illum, L. (2000). Transport of drugs from the nasal cavity to the central nervous system. Eur. J. Pharm. Sci. 11, 1-18.
    • (2000) Eur. J. Pharm. Sci , vol.11 , pp. 1-18
    • Illum, L.1
  • 23
    • 0037656051 scopus 로고    scopus 로고
    • Manganese: A high-octane dispute
    • Kaiser, J. (2003). Manganese: A high-octane dispute. Science 300, 926-928.
    • (2003) Science , vol.300 , pp. 926-928
    • Kaiser, J.1
  • 25
    • 0034090036 scopus 로고    scopus 로고
    • Intranasal instillation of aflatoxin b(1) in rats: Bioactivation in the nasal mucosa and neuronal transport to the olfactory bulb
    • Larsson, P., and Tjälve, H. (2000). Intranasal instillation of aflatoxin b(1) in rats: Bioactivation in the nasal mucosa and neuronal transport to the olfactory bulb. Toxicol. Sci. 55, 383-391.
    • (2000) Toxicol. Sci , vol.55 , pp. 383-391
    • Larsson, P.1    Tjälve, H.2
  • 26
    • 12844261708 scopus 로고    scopus 로고
    • Information processing in the mammalian olfactory system
    • Lledo P. M., Gheusi G., and Vincent, J. D. (2005). Information processing in the mammalian olfactory system. Physiol. Rev. 85 281-317.
    • (2005) Physiol. Rev , vol.85 , pp. 281-317
    • Lledo, P.M.1    Gheusi, G.2    Vincent, J.D.3
  • 27
    • 0031740593 scopus 로고    scopus 로고
    • Nasal route for direct delivery of solutes to the central nervous system: Fact or fiction?
    • Mathison, S., Nagilla, R., and Kompella, U. B. (1998). Nasal route for direct delivery of solutes to the central nervous system: Fact or fiction? J. Drug Target 5, 415-441.
    • (1998) J. Drug Target , vol.5 , pp. 415-441
    • Mathison, S.1    Nagilla, R.2    Kompella, U.B.3
  • 30
  • 31
    • 0036404750 scopus 로고    scopus 로고
    • Assessment of bioaccumulation, neuropathology, and neurobehavior following subchronic (90 days) inhalation in Sprague-Dawley rats exposed to manganese phosphate
    • Normandin, L., Carrier, G., Gardiner, P. F., Kennedy, G., Hazell, A. S.,Mergler, D., Butterworth, R. F., Philippe, S., and Zayed, J. (2002). Assessment of bioaccumulation, neuropathology, and neurobehavior following subchronic (90 days) inhalation in Sprague-Dawley rats exposed to manganese phosphate. Toxicol. Appl. Pharmacol. 183, 135-145.
    • (2002) Toxicol. Appl. Pharmacol , vol.183 , pp. 135-145
    • Normandin, L.1    Carrier, G.2    Gardiner, P.F.3    Kennedy, G.4    Hazell, A.S.5    Mergler, D.6    Butterworth, R.F.7    Philippe, S.8    Zayed, J.9
  • 33
    • 0033002368 scopus 로고    scopus 로고
    • Manganese neurotoxicity: A review of clinical features, imaging and pathology
    • Pal, P. K., Samii, A., and Calne, D. B. (1999). Manganese neurotoxicity: A review of clinical features, imaging and pathology. Neurotoxicology 20, 227-238.
    • (1999) Neurotoxicology , vol.20 , pp. 227-238
    • Pal, P.K.1    Samii, A.2    Calne, D.B.3
  • 34
    • 0036338284 scopus 로고    scopus 로고
    • Tracing odor-induced activation in the olfactory bulbs of mice using manganese-enhanced magnetic resonance imaging
    • Pautler, R. G., and Koretsky, A. P. (2002). Tracing odor-induced activation in the olfactory bulbs of mice using manganese-enhanced magnetic resonance imaging. Neuroimage 16, 441-448.
    • (2002) Neuroimage , vol.16 , pp. 441-448
    • Pautler, R.G.1    Koretsky, A.P.2
  • 37
    • 0041732394 scopus 로고    scopus 로고
    • Bioaccumulation and locomotor effects of manganese phosphate/sulfate mixture in Sprague-Dawley rats following subchronic (90 days) inhalation exposure
    • Salehi, F., Krewski, D., Mergler, D., Normandin, L., Kennedy, G., Philippe, S., and Zayed, J. (2003). Bioaccumulation and locomotor effects of manganese phosphate/sulfate mixture in Sprague-Dawley rats following subchronic (90 days) inhalation exposure. Toxicol. Appl. Pharmacol. 191, 264-271.
    • (2003) Toxicol. Appl. Pharmacol , vol.191 , pp. 264-271
    • Salehi, F.1    Krewski, D.2    Mergler, D.3    Normandin, L.4    Kennedy, G.5    Philippe, S.6    Zayed, J.7
  • 38
    • 0000078068 scopus 로고
    • Olfactory system
    • 2nd ed, G. Paxinos, Ed, pp, Academic Press, San Diego, CA
    • Shipley, M. T., McLean, J. H., and Ennis, M. (1995). Olfactory system. In: The Rat Nervous System, 2nd ed. (G. Paxinos, Ed.), pp. 899-926. Academic Press, San Diego, CA.
    • (1995) The Rat Nervous System , pp. 899-926
    • Shipley, M.T.1    McLean, J.H.2    Ennis, M.3
  • 39
    • 0028142012 scopus 로고
    • Axonal transport of manganese and its relevance to selective neurotoxicity in the rat basal ganglia
    • Sloot, W. N., and Gramsbergen, J. B. (1994). Axonal transport of manganese and its relevance to selective neurotoxicity in the rat basal ganglia. Brain Res. 657, 124-132.
    • (1994) Brain Res , vol.657 , pp. 124-132
    • Sloot, W.N.1    Gramsbergen, J.B.2
  • 41
    • 32544449942 scopus 로고    scopus 로고
    • Bioaccumulation and locomotor effects of manganese sulfate in Sprague-Dawley rats following subchronic (90 days) inhalation exposure
    • Tapin, D., Kennedy, G., Lambert, J., and Zayed, J. (2006). Bioaccumulation and locomotor effects of manganese sulfate in Sprague-Dawley rats following subchronic (90 days) inhalation exposure. Toxicol. Appl. Pharmacol. 211, 166-174.
    • (2006) Toxicol. Appl. Pharmacol , vol.211 , pp. 166-174
    • Tapin, D.1    Kennedy, G.2    Lambert, J.3    Zayed, J.4
  • 42
    • 0035211681 scopus 로고    scopus 로고
    • Astroglia as metal depots: Molecular mechanisms for metal accumulation, storage and release
    • Tiffany-Castiglion, E., and Qian, Y. (2001). Astroglia as metal depots: Molecular mechanisms for metal accumulation, storage and release. Neurotoxicology 22, 577-592.
    • (2001) Neurotoxicology , vol.22 , pp. 577-592
    • Tiffany-Castiglion, E.1    Qian, Y.2
  • 43
    • 0033042991 scopus 로고    scopus 로고
    • Uptake of metals in the brain via olfactory pathways
    • Tjälve, H., and Henriksson, J. (1999). Uptake of metals in the brain via olfactory pathways. Neurotoxicology 20, 181-195.
    • (1999) Neurotoxicology , vol.20 , pp. 181-195
    • Tjälve, H.1    Henriksson, J.2
  • 44
    • 0030444977 scopus 로고    scopus 로고
    • Uptake of manganese and cadmium from the nasal mucosa into the central nervous systemvia olfactory pathways in rats
    • Tjälve, H., Henriksson, J., Tallkvist, J., Larsson, B. S., and Lindquist, N. G. (1996). Uptake of manganese and cadmium from the nasal mucosa into the central nervous systemvia olfactory pathways in rats. Pharmacol.Toxicol. 79, 347-356.
    • (1996) Pharmacol.Toxicol , vol.79 , pp. 347-356
    • Tjälve, H.1    Henriksson, J.2    Tallkvist, J.3    Larsson, B.S.4    Lindquist, N.G.5
  • 45
    • 0029046969 scopus 로고
    • Uptake and transport of manganese in primary and secondary olfactory neurones in pike
    • Tjälve, H., Mejare, C., and Borg-Neczak, K. (1995). Uptake and transport of manganese in primary and secondary olfactory neurones in pike. Pharmacol. Toxicol. 77, 23-31.
    • (1995) Pharmacol. Toxicol , vol.77 , pp. 23-31
    • Tjälve, H.1    Mejare, C.2    Borg-Neczak, K.3
  • 46
    • 0034653940 scopus 로고    scopus 로고
    • Pharmacokinetics of inhaled manganese phosphate in male Sprague-Dawley ats following subacute (14-day) exposure
    • Vitarella, D., Wong, B. A., Moss, O. R., and Dorman, D. C. (2000). Pharmacokinetics of inhaled manganese phosphate in male Sprague-Dawley ats following subacute (14-day) exposure. Toxicol. Appl. Pharmacol. 163, 279-285.
    • (2000) Toxicol. Appl. Pharmacol , vol.163 , pp. 279-285
    • Vitarella, D.1    Wong, B.A.2    Moss, O.R.3    Dorman, D.C.4
  • 47
    • 0031736969 scopus 로고    scopus 로고
    • Brain uptake of dihydroergotamine after intravenous and nasal administration in the rat
    • Wang, Y., Aun, R., and Tse, F. L. (1998). Brain uptake of dihydroergotamine after intravenous and nasal administration in the rat. Biopharm. Drug Dispos. 19, 571-575.
    • (1998) Biopharm. Drug Dispos , vol.19 , pp. 571-575
    • Wang, Y.1    Aun, R.2    Tse, F.L.3
  • 48
    • 0037231207 scopus 로고    scopus 로고
    • Manganese distribution across the blood-brain barrier. Ii. Manganese efflux from the brain does not appear to be carrier mediated
    • Yokel, R. A., Crossgrove, J. S., and Bukaveckas, B. L. (2003). Manganese distribution across the blood-brain barrier. Ii. Manganese efflux from the brain does not appear to be carrier mediated. Neurotoxicology 24, 15-22.
    • (2003) Neurotoxicology , vol.24 , pp. 15-22
    • Yokel, R.A.1    Crossgrove, J.S.2    Bukaveckas, B.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.