Heat shock protein 90 modulates endothelial nitric oxide synthase activity and vascular reactivity in the newborn piglet pulmonary circulation

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 292, Issue 6, 2007, Pages

  Aschner, Judy L ^a,b,c   Foster, Susan L ^b   Kaplowitz, Mark ^a,b   Zhang, Yongmei ^a,b   Zeng, Heng ^a   Fike, Candice D ^a,b  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c MONROE CARELL JR CHILDREN S HOSPITAL AT VANDERBILT   (United States)

Author keywords

Geldanamycin; Isolated perfused lungs; Pulmonary resistance arteries; Radicicol; Superoxide

Indexed keywords

ACETYLCHOLINE; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; HYDROETHIDINE; M40401; NITRIC OXIDE; OXYGEN; RADICICOL; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL DIAMETER; BLOOD VESSEL REACTIVITY; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CONFOCAL MICROSCOPY; DRUG INHIBITION; DRUG MANUFACTURE; ENDOTHELIUM CELL; ENZYME ACTIVITY; IMMUNOPRECIPITATION; LUNG ARTERY PRESSURE; LUNG CIRCULATION; LUNG ENDOTHELIUM; LUNG PERFUSION; METABOLITE; MODULATION; NEWBORN; NONHUMAN; OXIDATION; PIGLET; PRECIPITATION; PRIORITY JOURNAL; PULMONARY ARTERY;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANIMALS, NEWBORN; BENZOQUINONES; CELLS, CULTURED; CYCLIC GMP; DICARBETHOXYDIHYDROCOLLIDINE; ENDOTHELIAL CELLS; ENZYME INHIBITORS; HSP90 HEAT-SHOCK PROTEINS; LACTAMS, MACROCYCLIC; MACROLIDES; MICROCIRCULATION; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PULMONARY ARTERY; PULMONARY CIRCULATION; SUPEROXIDES; SWINE; VASCULAR RESISTANCE;

EID: 34447566908     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00252.2006     Document Type: Article

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