Microsatellite instability indicative of defects in the major mismatch repair genes is rare in patients with B-cell chronic lymphocytic leukemia: Evaluation with disease stage and family history

Leukemia and Lymphoma

Volumn 48, Issue 7, 2007, Pages 1320-1322

  Sellick, G S ^a   Lubbe, S J ^a   Matutes, E ^a   Catovsky, D ^a   Houlston, R S ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Chronic B cell lymphocytic leukemia (B CLL); Microsatellite instability (MSI); Mismatch repair (MMR)

Indexed keywords

NUCLEOTIDE;

ADULT; AGED; ARTICLE; B CELL LEUKEMIA; CANCER STAGING; CHRONIC LYMPHATIC LEUKEMIA; CORRELATION ANALYSIS; DISEASE MARKER; FAMILY HISTORY; FAMILY STUDY; FEMALE; GENE IDENTIFICATION; GENETIC SCREENING; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; ONCOGENE; PRIORITY JOURNAL;

AGED; DNA MISMATCH REPAIR; DNA REPAIR; FAMILY HEALTH; FEMALE; GENETIC MARKERS; HUMANS; LEUKEMIA, B-CELL, CHRONIC; MALE; MICROSATELLITE INSTABILITY; MICROSATELLITE REPEATS; MIDDLE AGED; TUMOR MARKERS, BIOLOGICAL;

EID: 34447566088     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.1080/10428190701361844     Document Type: Article

References (17)

1. Wierda, W. (2004) Molecular biology of chronic lymphocytic leukaemia. Chronic Lymphocytic Leukemia, pp. 77-94. Human Press, Totowa, New Jersey
2. Fulop, Z., Csernus, B., Timar, B., Szepesi, A. and Matolcsy, A. (2003) Microsatellite instability and hMLH1 promoter hypermethylation in Richter's transformation of chronic lymphocytic leukemia. Leukemia, 17, pp. 411-415.
3. Gartenhaus, R., Johns III, M. M., Wang, P., Rai, K. and Sidransky, D. (1996) Mutator phenotype in a subset of chronic lymphocytic leukemia. Blood, 87, pp. 38-41.
4. Niv, E., Bomstein, Y., Yuklea, M. and Lishner, M. (2005) Microsatellite instability in patients with chronic B-cell lymphocytic leukaemia. Br J Cancer, 92, pp. 1517-1523.
5. Sanz-Vaque, L., Colomer, D. and Bosch, F. (2001) Microsatellite instability analysis in typical and progressed mantle cell lymphoma and B-cell chronic lymphocytic leukemia. Haematologica, 86, pp. 181-186.
6. Volpe, G., Gamberi, B. and Pastore, C. (1996) Analysis of microsatellite instability in chronic lymphoproliferative disorders. Ann Hematol, 72, pp. 67-71.
7. Kolodner, R. D. and Marsischky, G. T. (1999) Eukaryotic DNA mismatch repair. Curr Opin Genet Dev, 9, pp. 89-96.
8. Malkhosyan, S., Rampino, N., Yamamoto, H. and Perucho, M. (1996) Frameshift mutator mutations. Nature, 382, pp. 499-500.
9. Ionov, Y., Peinado, M. A., Malkhosyan, S., Shibata, D. and Perucho, M. (1993) Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature, 363, pp. 558-561.
10. Aaltonen, L. A., Peltomaki, P. and Leach, F. S. (1993) Clues to the pathogenesis of familial colorectal cancer. Science, 260, pp. 812-816.
11. Aaltonen, L. A., Peltomaki, P. and Mecklin, J. P. (1994) Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients. Cancer Res, 54, pp. 1645-1648.
12. Landgren, O., Pfeiffer, R. M. and Stewart, L. (2007) Risk of second malignant neoplasms among lymphoma patients with a family history of cancer. Int J Cancer, 120, pp. 1099-1102.
13. Zhou, X. P., Hoang, J. M., Cottu, P., Thomas, G. and Hamelin, R. (1997) Allelic profiles of mononucleotide repeat microsatellites in control individuals and in colorectal tumors with and without replication errors. Oncogene, 15, pp. 1713-1718.
14. Trusky, C. L., Sepulveda, A. R. and Hunt, J. L. (2006) Assessment of microsatellite instability in very small microdissected samples and in tumor samples that are contaminated with normal DNA. Diagn Mol Pathol, 15, pp. 63-69.
15. Pyatt, R., Chadwick, R. B., Johnson, C. K., Adebamowo, C., de la Chapelle, A. and Prior, T. W. (1999) Polymorphic variation at the BAT-25 and BAT-26 loci in individuals of African origin. Implications for microsatellite instability testing. Am J Pathol, 155, pp. 349-353.
16. Laiho, P., Launonen, V. and Lahermo, P. (2002) Low-level microsatellite instability in most colorectal carcinomas. Cancer Res, 62, pp. 1166-1170.
17. Boland, C. R., Thibodeau, S. N. and Hamilton, S. R. (1998) A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res, 58, pp. 5248-5257.