Synthesis and antitumour activity of the primin (2-methoxy-6-n-pentyl-1,4-benzoquinone) and analogues

Medicinal Chemistry

Volumn 3, Issue 4, 2007, Pages 369-372

  Brondani, D J ^a   Nascimento, C R M ^a   Moreira, D R de M ^a   Lima Leite, A C ^a   de Souza, I A ^b   Bieber, L W ^a  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^b DEPARTAMENTO DE MICOLOGIA   (Brazil)

Author keywords

Antitumour agent; Benzoquinone; Primin derivative; Prodrug

Indexed keywords

2 METHOXY 1,4 HYDROQUINONE DI(2' TETRAHYDROPYRANYL) ETHER; 2 METHOXY 6 N PENTYLHYDROQUINONE DI(2' TETRAHYDROPYRANYL) ETHER; ANTINEOPLASTIC AGENT; BENZOQUINONE DERIVATIVE; DIMETHYLCARBAMIC ACID 1 ISOPROPYL 3 METHYLPYRAZOL 5 YL ESTER; HYDROQUINONE DERIVATIVE; MICONIDIN; NATURAL PRODUCT; PLANT EXTRACT; PRIMULA OBCONICA EXTRACT; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BEHAVIOR DISORDER; CANCER INHIBITION; CANCER MORTALITY; CONTROLLED STUDY; DRUG FATALITY; DRUG STRUCTURE; DRUG SYNTHESIS; EHRLICH ASCITES TUMOR; EXPERIMENTAL NEOPLASM; FEMALE; HYPOXEMIA; MALE; MOUSE; NONHUMAN; PRIMULA OBCONICA; PRIMULACEAE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SARCOMA; SINGLE DRUG DOSE; STRUCTURE ACTIVITY RELATION; TOXICITY TESTING;

ANIMALS; ANTINEOPLASTIC AGENTS; BEHAVIOR, ANIMAL; BENZOQUINONES; MALE; MICE; MOLECULAR STRUCTURE; NEOPLASM TRANSPLANTATION; NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

EID: 34447565001     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340607781024410     Document Type: Article

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