Mitochondrial transmembrane potential loss caused by reactive oxygen species plays a major role in sodium selenite-induced apoptosis in NB4 cells

Acta Academiae Medicinae Sinicae

Volumn 29, Issue 3, 2007, Pages 324-328

  Wei, Wei ^a   Han, Bing She ^a   Guan, Li Ying ^a   Huang, Fang ^a   Feng, Lei ^a   Yang, Yang ^a   Xu, Cai Min ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Apoptosis; Mitochondrial transmembrane potential; Reactive oxygen species

Indexed keywords

BUTHIONINE SULFOXIMINE; CYTOCHROME C; PROTEIN BAX; PROTEIN BCL XL; PROTEIN BID; REACTIVE OXYGEN METABOLITE; SODIUM SELENITE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKEMIA CELL; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PROMYELOCYTIC LEUKEMIA; PROTEIN LOCALIZATION; PROTEIN SECRETION; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CELL LINE, TUMOR; CYTOCHROMES C; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE OXYGEN SPECIES; SODIUM SELENITE;

EID: 34447558135     PISSN: 1000503X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Lanotte VM-TM, Najman S, Balerini P, et al. NB4, a maturation inducible cell line with t (15; 17) marker isolated from a human acute promyelocytic leukemia (M3) [J]. Blood, 1991, 177(5):1080-1086.
2. Chen Z, Chen GQ, Shen ZX, et al. Treatment of acute promyelocytic leukemia with arsenic compounds: in vitro and in vivo studies [J]. Semin Hematol, 2001, 38(1):26-36.
3. Grignani F, Fagioli M, Alcalay M, et al. Acute promyelocytic leukemia: from genetics to treatment [J]. Blood, 1994, 83(1):10-25.
4. 3 combination yields a high quality remission and survival in newly diagnosed acute promyelocytic leukemia [J]. Proc Natl Acad Sci USA, 2004, 101(15):5328-5335.
5. Rayman MP. The importance of selenium to human health [J]. Lancet, 2000, 356(9225):233-241.
6. Taylor PR, Parnes HL, Lippman SM. Science peels the onion of selenium effects on prostate carcinogenesis [J]. J Natl Cancer Inst, 2004, 96(9):645-647.
7. Le Bras M, Clement MV, Pervaiz S, et al. Reactive oxygen species and the mitochondrial signaling pathway of cell death [J]. Histol Histopathol, 2005, 20(1):205-219.
8. Marso I, Brenner C, Zamzami N. The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins [J]. J Exp Med, 1998, 187(8):1261-1271.
9. Wei MC, Zong WX, Cheng EH, et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death [J]. Science, 2001, 292(5517):727-730.
10. 2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors [J]. Cell, 1998, 94(4):481-490.
11. Philchenkov A. caspases: potential targets for regulating cell death [J]. J Cell Mol Med, 2004, 8(4):432-444.