Pharmacological classification of histamine H3 receptor agents across species is attributable to transmembrane 3 sequence differences

Inflammation Research

Volumn 56, Issue SUPPL. 1, 2007, Pages

  Esbenshade, T A ^a   Estvander, B R ^a   Miller, T R ^a   Baranowski, J L ^a   Sharma, R ^a   Hancock, A A ^a   Krueger, K M ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPENTYL; FUB 322; HISTAMINE AGONIST; HISTAMINE H3 RECEPTOR; IMHEXAMINE; IMOPROXYFAN; IMPENTAMINE; IODOPHENPROPIT; UNCLASSIFIED DRUG; VUF 5681;

ANIMAL CELL; COGNITION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG CLASSIFICATION; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; LIGAND BINDING; NEUROTRANSMITTER RELEASE; NONHUMAN; OBESITY; SEQUENCE HOMOLOGY; SLEEP;

ANIMALS; CELL LINE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HISTAMINE AGONISTS; HUMANS; IMIDAZOLES; LIGANDS; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, HISTAMINE H3;

EID: 34447555588     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-006-0522-x     Document Type: Conference Paper

References (6)

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4. Ligneau X, Morisset S, Tardivel-Lacombe J, Gbahou F, Ganellin CR, Stark H et al. Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain. Br J Pharmacol. 2000; 131: 1247-50.
5. Esbenshade TA, Hancock AA. Characterization of histaminergic receptors. Curr Prot Pharmacol 2000; 1: 1.19.1-1.19.19.
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