Possible role of carbonic anhydrase in rat pancreatic islets: Enzymatic, secretory, metabolic, ionic, and electrical aspects

American Journal of Physiology - Endocrinology and Metabolism

Volumn 292, Issue 6, 2007, Pages

  Sener, Abdullah ^a   Jijakli, Hassan ^a   Asl, Saleh Zahedi ^a   Courtois, Philippe ^a   Yates, Allen P ^b   Meuris, Sylvain ^a   Best, Leonard C ^b   Malaisse, Willy J ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Acetazolamide; Bicarbonate production; Bioelectrical activity; D glucose metabolism; Insulin secretion

Indexed keywords

ACETAZOLAMIDE; ANION CHANNEL; CALCIUM; CARBONATE DEHYDRATASE; GLUCOSE; HYDROCHLOROTHIAZIDE; INSULIN; ISOENZYME; MALIC ACID; PYRUVIC ACID; SODIUM AZIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOENERGY; CALCIUM CELL LEVEL; CELL PH; CIRCULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOLIC FRACTION; ELECTRIC CURRENT; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME METABOLISM; ENZYME RELEASE; FEMALE; GLUCONEOGENESIS; GLUCOSE OXIDATION; GLYCOLYSIS; INSULIN RELEASE; METABOLITE; MITOCHONDRION; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PAROTID GLAND; PRIORITY JOURNAL; RAT; TISSUE HOMOGENATE;

ACETAZOLAMIDE; ANIMALS; BICARBONATES; CARBONIC ANHYDRASE INHIBITORS; CARBONIC ANHYDRASES; ELECTROPHYSIOLOGY; FEMALE; GLUCOSE; HYDROGEN-ION CONCENTRATION; INSULIN; INTRACELLULAR FLUID; ISLETS OF LANGERHANS; MALE; PAROTID GLAND; RATS; RATS, WISTAR; SODIUM AZIDE;

EID: 34447554567     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00631.2006     Document Type: Article

References (24)

1. Berliner RW, Orloff J. Carbonic anhydrase inhibitors. Pharmacol Rev 8: 137-174, 1956.
2. Best L. Glucose and α-ketoisocaproate induce transient inward currents in rat pancreatic beta cells. Diabetologia 40: 1-6, 1997.
3. Best L. Inhibition of glucose-induced electrical activity by 4-hydroxytamoxifen in rat pancreatic β-cells. Cell Signal 14: 69-73, 2002.
4. Best L. How does glucose evoke electrical activity in the pancreatic beta-cell? Diabetes Metab 26: 3S18-3S24, 2002.
5. Best L, Elliott AC. Changes in 2′7′-(biscarboxyethyl) 5′(6′)carboxyfluorescein, fura-2 and autofluorescence in intact rat pancreatic islets in response to nutrients and nonnutrients. Mol Cell Endocrinol 111: 191-198, 1995.
6. - influx and cellular pH in glucose-stimulated pancreatic islets. FEBS Lett 154: 97-100, 1983.
7. Jijakli H, Zhang H, Sener A, Malaisse WJ. Properties of pancreatic islet beta cells obtained by immunomagnetic purification (Abstract). Diabetologia 45: A139, 2002.
8. 2+ in aequorin-expressing INS-1 cells. J Clin Invest 98: 2524-2538, 1996.
9. Landolfi C, Marchetti M, Ciocci G, Milanese C. Development and pharmacological characterization of a modified procedure for the measurement of carbonic anhydrase activity. J Pharmacol Toxicol Methods 38: 169-172, 1997.
10. Lowry O, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement by the Folin phenol reagent. J Biol Chem 193: 265-275, 1951.
11. MacDonald MJ. Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion. J Biol Chem 270: 20051-20058, 1995.
12. Malaisse WJ, Magetto C, Leclercq-Meyer V, Sener A. Interference of glycogenolysis with glycolysis in pancreatic islets from glucose-infused rats. J Clin Invest 91: 432-436, 1993.
13. Malaisse WJ, Sener A. Hexose metabolism in pancreatic islets. Feedback control of glucose oxidation by functional events. Biochim Biophys Acta 971: 246-254, 1988.
14. Malaisse-Lagae F, Malaisse WJ. Insulin release by pancreatic islets. In: Methods in Diabetes Research, edited by Larner J, and Pohl S. New York: Wiley, 1984, vol. 1, p. 174-152.
15. Mangos JA, McSherry NR, Butcher R, Irvin K, Barber T. Dispersed parotid cells. I. Morphological and functional characterization. Am J Physiol 229: 553-559, 1975.
16. Murakami H, Sly WS. Purification and characterization of human salivary carbonic anhydrase. J Biol Chem 262: 1382-1388, 1987.
17. Ogawa Y, Fernley RT, Ito R, Ijuhin N. Immunohistochemistry of carbonic anhydrase isozymes VI and II during development of the rat salivary glands. Histochem Cell Biol 110: 81-88, 1998.
18. Okuyama T, Sato S, Zhu XL, Waheed A, Sly WS. Human carbonic anhydrase IV: cDNA cloning, sequence comparison, and expression in COS cell membranes. Proc Natl Acad Sci USA 89: 1315-1319, 1992.
19. Parkkila AK, Scarim AL, Parkkila S, Waheed A, Corbett JA, Sky WS. Expression of carbonic anhydrase V in pancreatic beta cells suggests role for mitochondrial carbonic anhydrase in insulin secretion. J Biol Chem 273: 24620-24623, 1998.
20. Sener A, Best LC, Yates AP, Kadiata MM, Olivares E, Louchami K, Jijakli H, Ladrière L, Malaisse WJ. Stimulus-secretion coupling of arginine-induced insulin release. Comparison between the cationic amino acid and its methyl esters. Endocrine 13: 329-340, 2000.
21. Sener A, Blachier F, Malaisse WJ. Production of urea but absence of urea cycle in pancreatic islet cells. Med Sci Res 16: 483-484, 1988.
22. Sener A, Malaisse WJ. The metabolism of glucose in pancreatic islets. Diabete Metab 4: 127-133, 1978.
23. --activated ATPase in pancreatic islets. FEBS Lett 105: 40-42, 1979.
24. Thatcher BJ, Doherty AE, Orvisky E, Martin BM, Hankin RI. Gustin from human parotid saliva is carbonic anhydrase VI. Biochem Biophys Res Commun 250: 635-641, 1998.