Neoadjuvant imatinib in a locally advanced gastrointestinal stromal tumour (GIST) of the rectum: A rare case of two GISTs within a family without a familial GIST syndrome

European Journal of Gastroenterology and Hepatology

Volumn 19, Issue 8, 2007, Pages 711-713

  Mandalà, Mario ^a   Pezzica, Ezio ^a   Tamborini, Elena ^b   Guerra, Ugo ^c   Lagonigro, Stefania M ^b   Forloni, Bruno ^a   Barni, Sandro ^a  

^a TREVIGLIO HOSPITAL   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

^c OSPEDALI RIUNITI   (Italy)

Author keywords

Gastrointestinal stromal tumour; Gleevec; Preoperative therapy

Indexed keywords

ANTINEOPLASTIC AGENT; FLUORODEOXYGLUCOSE F 18; IMATINIB; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; STEM CELL FACTOR RECEPTOR;

ADJUVANT CHEMOTHERAPY; ADULT; ADVANCED CANCER; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CASE REPORT; DRUG UPTAKE; EXON; FAMILIAL DISEASE; GASTROINTESTINAL STROMAL TUMOR; GENE MUTATION; HUMAN; HUMAN TISSUE; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RECTUM CARCINOMA; RECTUM TUMOR; RNA EXTRACTION; TUMOR BIOPSY;

ANTINEOPLASTIC AGENTS; CHEMOTHERAPY, ADJUVANT; FAMILY HEALTH; GASTROINTESTINAL STROMAL TUMORS; HUMANS; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; PIPERAZINES; POSITRON-EMISSION TOMOGRAPHY; PYRIMIDINES; RECTAL NEOPLASMS;

EID: 34447542205     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.meg.0000230087.83792.1f     Document Type: Article

References (4)

1. Blay JY, Bonvalot S, Casali P, Choi H, Debiec-Richter M, DeiTos AP, et al. Consensus meeting for the management of gastrointestinal stromal tumors. Report of the GIST Consensus Conference of 20-21 March 2004, under the auspices of ESMO. Ann Oncol 2005; 16:566-578.
2. Tamborini E, Bonadiman L, Greco A, Albertini V, Negri T, Gronchi A, et al. A new mutation in the KIT ATP pocket causes acquired resistance to imatinib in a gastrointestinal stromal tumor patient. Gastroenterology 2004; 127:294-299.
3. Corless CL, Fletcher JA, Heinrich MC. Biology of gastrointestinal stromal tumors. J Clin Oncol 2004; 22:3813-3825.
4. Li FP, Fletcher JA, Heinrich MC, Garber JE, Sallan SE, Curiel-Lewandrowski C, et al. Familial gastrointestinal stromal tumor syndrome: phenotypic and molecular features in a kindred. J Clin Oncol 2005; 23:2735-2743.