Effect of delivered dosage of cigarette smoke toxins on the levels of urinary biomarkers of exposure

Cancer Epidemiology Biomarkers and Prevention

Volumn 16, Issue 7, 2007, Pages 1408-1415

  Melikian, Assieh A ^a   Djordjevic, Mirjana V ^b   Chen, Shuquan ^c   Richie Jr , John ^d   Stellman, Steven D ^e  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c AMERICAN HEALTH FOUNDATION   (United States)

^d PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^e Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 HYDROXYPYRENE; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANOL; 4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; BENZO[A]PYRENE; BIOLOGICAL MARKER; CIGARETTE SMOKE; COTININE; NICOTINE; TOXIN;

ADULT; AFRICAN AMERICAN; ARTICLE; CIGARETTE SMOKING; CORRELATION ANALYSIS; EXPOSURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; URINE LEVEL;

ADMINISTRATION, INHALATION; ADOLESCENT; ADULT; BIOLOGICAL MARKERS; CARCINOGENS; COTININE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL EXPOSURE; FEMALE; GANGLIONIC STIMULANTS; HUMANS; MALE; MIDDLE AGED; NICOTINE; POLYCYCLIC HYDROCARBONS, AROMATIC; SMOKING; TOXINS, BIOLOGICAL; URINALYSIS;

EID: 34447539925     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-06-1097     Document Type: Article

References (37)

1. International Agency for Research on Cancer. Tobacco smoke and involuntary smoking. IARC monographs on the evaluation of carcinogenic risks of chemicals to humans, vol. 83. Lyon (France): IARC; 2004. pp. 1-1438.
2. U.S. Department of Health and Human Services. The health consequences of smoking: a report of the surgeon general. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Smoking and Health, Superintendent of Documents. Washington (DC): U.S. Government Printing Office; 2004.
3. Bridges RB, Combs JG, Hamble JW, Turbek JA, Rehm SR, Haley NJ. Puffing topography as a determinant of smoke exposure. Pharmacol Biochem Behav 1990;37:29-39.
4. Hofer I, Nil R, Batting K. Nicotine yield as determinant of smoke exposure indicators and puffing behavior. Pharmacol Biochem Behav 1991;40:139-49.
5. Kozlowski LT, O'Connor RJ. Cigarette filter ventilation is a defective design because of misleading taste, bigger puffs, and blocked vents. Tob Control 2002;11 Suppl 1:140-50.
6. Djordjevic MV, Stellman SD, Zang E. Doses of nicotine and lung carcinogens delivered to cigarette smokers. J Natl Cancer Inst 2000;92:106-11.
7. Melikian AA, Djordjevic MV, Hosey J, et al. Gender differences relative to smoking behavior and emissions of toxins from mainstream cigarette smoke. Nicotine Tob Res 2007;9:377-87.
8. Hecht SS, Murphy SE, Carmella SG, et al. Similar uptake of lung carcinogens by smokers of regular, light, and ultralight cigarettes. Cancer Epidemiol Biomarkers Prev 2005;14:693-8.
9. Melikian AA, Hosey J, Zhang J, et al. Reduction of urinary metabolites of tobacco carcinogens in smokers who switched from conventional light cigarettes to a new cigarette with low levels of tobacco-specific nitrosamines and a modified filter tip [abstract 6414]. Proc Am Assoc Cancer Res 2003;44:1470.
10. Zedler BK, Kinser R, Oey J, et al. Biomarkers of exposure and potential harm in adult smokers of 3-7 mg tar yield (Federal Trade Commission) cigarettes and in adult non-smokers. Biomarkers 2006;11:201-20.
11. Feng S, Roethig HJ, Liang Q, et al. Evaluation of urinary 1-hydroxypyrene, S-phenylmercapturic acid, trans,trans-muconic acid, 3-methyladenine, 3-ethyladenine, 8-hydroxy-2′-deoxyguanosine and thioethers as biomarkers of exposure to cigarette smoke. Biomarkers 2006;11:28-52.
12. Shields PG. Tobacco smoking, harm reduction, and biomarkers. J Natl Cancer Inst 2002;94:1435-44.
13. Muscat J, Djordjevic MV, Stellman SD, Richie JP, Jr. Racial differences in exposure and glucuronidation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-butanone (NNK). Cancer 2005;103:1420-6.
14. Djordjevic MV, Fan J, Ferguson S, Hoffmann D. Self-regulation of smoking intensity. Smoke yields of the low-nicotine, low-'tar' cigarettes. Carcinogenesis 1995;16:2015-21.
15. Djordjevic MV, Hoffmann D, Hoffmann I. Nicotine regulates smoking patterns. Prev Med 1997;26:435-40.
16. Brunnemann KD, Hoffmann D. Analytical studies on tobacco-specific N-nitrosamines in tobacco and tobacco smoke. Crit Rev Toxicol 1991;21:235-40.
17. Melikian AA, Sun P, Prokopczyk B, et al. Identification of benzo[a]pyrene metabolites in cervical mucus and DNA adducts in cervical tissues in humans by gas chromatography-mass spectrometry. Cancer Lett 1999;146:127-34.
18. Singh R, Tucek M, Maxa K, Tenglerova J, Weyand EH. A rapid and simple method for the analysis of 1-hydroxypyrene glucuronide: a potential biomarker for polycyclic aromatic hydrocarbon exposure. Carcinogenesis 1995;16:2909-15.
19. Lee CK, Cho SH, Kang JW, et al. Comparison of three analytical methods for 1-hydroxypyrene glucuronide in urine after non-occupational exposure to polycyclic aromatic hydrocarbons. Toxicol Lett 1999;108:209-15.
20. Carmella SG, Akerkar S, Hecht SS. Metabolites of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers' urine. Cancer Res 1993;53:721-4.
21. Melikian AA, Qu Q, Shore R, et al. Personal exposure to different levels of benzene and its relationships to the urinary metabolites S- phenylmercapturic acid and trans, trans-muconic acid. J Chromatogr B Analyt Technol Biomed Life Sci 2002;778:211-21.
22. Benowitz NL, Jacob P 3rd. Effects of cigarette smoking and carbon monoxide on nicotine and cotinine metabolism. Clin Pharmacol Ther 2000;67:653-9.
23. Lee BL, Benowitz NL, Jacob P 3rd. Influence of tobacco abstinence on the disposition kinetics and effects of nicotine. Clin Pharmacol Ther 1987;41:474-9.
24. Schoedel KA, Sellers EM, Palmour R, Tyndale RF. Down-regulation of hepatic nicotine metabolism and a CYP2A6-like enzyme in African green monkeys after long-term nicotine administration. Mol Pharmacol 2003;63:96-104.
25. Law MR, Morris JK, Watt HC, Wald NJ. The dose-response relationship between cigarette consumption, biochemical markers, and risk of lung cancer. Br J Cancer 1997;75:1690-3.
26. Vineis P, Alavanja M, Garte S. Dose-response relationship in tobacco-related cancers of bladder and lung: a biochemical interpretation. Int J Cancer 2004;108:2-7.
27. Vineis P, Kogevinas M, Simonato L, Brennan P, Boffetta P. Levelling-off of the risk of lung and bladder cancer in heavy smokers: an analysis based on multicentric case-control studies and a metabolic interpretation. Mutat Res 2000;463:103-10.
28. Wynder EL, Stellman SD. The comparative epidemiology of tobacco-related cancers. Cancer Res 1977;37:4608-22.
29. Lubin JH, Caporaso NE. Cigarette smoking and lung cancer: modeling total exposure and intensity. Cancer Epid Biomarkers Prev 2006;15:517-23.
30. Haiman CA, Stram DO, Wilkens LR, et al. Ethnic and racial differences in the smoking-related risk of lung cancer. N Engl J Med 2006;354:333-42.
31. Harris JE, Thun MJ, Mondul AM. Cigarette tar yields in relation to mortality from lung cancer in cancer prevention study II prospective cohort, 1982-8. BMJ 2004;328:72-9.
32. Melikian AA, Djordjevic MV. The role of smoking topography in assessing human smoking and its utility for information machine smoking protocols. 7th Scientific Advisory Study Group on Tobacco Product Regulations (formerly known as SACTob) meeting. Montebello (Canada); September 2004.
33. th Annual Meeting of Society for Research on Nicotine and Tobacco (SNRT), 2006.
34. Simpson CD, Wu MT, Christiani DC, Santella RM, Carmella SG, Hecht SS. Determination of r-7,t-8,9,c-10-tetrahydroxy-7,8,9,10-tetrahydrobenzo[a] pyrrene in human urine by gas chromatography/negative ion chemical ionization/mass spectrometry. Chem Res Toxicol 2000;13:271-80.
35. Jongeneelen FJ. Methods for routine biological monitoring of carcinogenic PAH-mixtures. Sci Total Environ 1997;199:141-9.
36. Tsai HT, Wu MT, Hauser R, et al. Exposure to environmental tobacco smoke and urinary 1-hydroxypyrene levels in preschool children. Kaohsiung J Med Sci 2003;19:97-104.
37. Melikian AA, Malpure S, John A, et al. Determination of hemoglobin and serum albumin adducts of benzo[a]pyrene by gas chromatography-mass spectrometry in humans and their relation to exposure and to other biological markers. Polycyclic Aromatic Compounds 1999;17:125-34.