Reducing susceptibility to bacteremia after experimental burn injury: A role for selective decontamination of the digestive tract

Journal of Applied Physiology

Volumn 102, Issue 6, 2007, Pages 2207-2216

  Horton, Jureta W ^a   Maass, David L ^a   White, Jean ^a   Minei, Joseph P ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Adult Sprague Dawley rats; Inflammatory cytokines; Intratracheal bacterial challenge; Isolated cardiac myocytes; Oral antibiotics; Postburn cardiac function; Streptococcus pneumoniae

Indexed keywords

COLISTIN; FLUCYTOSINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; TOBRAMYCIN; TUMOR NECROSIS FACTOR ALPHA; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC THERAPY; ARTICLE; ASEPSIS; BACTEREMIA; BURN; CONTROLLED STUDY; CYTOKINE RELEASE; DIGESTIVE SYSTEM; DISEASE PREDISPOSITION; EXPERIMENTAL STUDY; HEART DISEASE; HEART FUNCTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CELL; MALE; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; RAT; SEPSIS; STATISTICAL ANALYSIS; TREATMENT DURATION;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTEREMIA; DISEASE MODELS, ANIMAL; GASTROINTESTINAL TRACT; MALE; MYOCARDITIS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 34447530821     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01365.2005     Document Type: Article

References (35)

1. Adams CA Jr, Hauser CJ, Adams JM, Fekete Z, Xu DZ, Sambol JT, Deitch EA. Trauma-hemorrhage-induced neutrophil priming is prevented by mesenteric lymph duct ligation. Shock 18: 513-517, 2002.
2. Baron P, Traber LD, Traber DL, Nguyen T, Hollyoak M, Heggers JP, Herndon DN. Gut failure and translocation following burn and sepsis. J Surg Res 57: 197-204, 1994.
3. Barret JP, Jeschke MG, Herndon DN. Selective decontamination of the digestive tract in severely burned pediatric patients. Burns 27: 439-445, 2001.
4. Bonten MJM, Joore HCA, de Jongh BM, Kluytmans J, Kuijper EJ, van Leeuwen HJ, de Smet AMGA, Vandenbroucke-Grauls C. Selective decontamination of the digestive tract: all questions answered? Crit Care 7: 203-205, 2003.
5. Chung DH, Herndon DN. Multiple converging mechanisms for postburn intestinal barrier dysfunction. Crit Care Med 32: 1730-1739, 2004.
6. Collard HR, Saint S, Matthay MA. Prevention of ventilator-associated pneumonia: an evidence-based systematic review. Ann Intern Med 138: 494-501, 2003.
7. D'Amico R, Pifferi S, Leonetti C, Torri V, Tinazzi A, Liberati A. Effectiveness of antibiotic prophylaxis in critically ill adult patients: systematic review of randomized controlled trials. Br Med J 316: 1275-1285, 1998.
8. Davis CC, Mellencamp MA, Preheim LC. A model of pneumococcal pneumonia in chronically intoxicated rats. J Infect Dis 163: 799-805, 1991.
9. de Jonge E, Schultz MJ, Spanjaard L, Bossuyt PMM, Vroom MB, Dankert J, Kesecioglu J. Effects of selective decontamination of digestive tract on mortality and acquisition of resistant bacterial in intensive care: a randomized controlled trial. Lancet 362: 1011-1016, 2003.
10. de La Cal MA, Cerda E, Garcia-Hierro P, van Saene HK, Gon Santos D, Negro E, Lorente JA. Survival benefit in critically ill burned patients receiving selective decontamination of the digestive tract: a randomized, placebo-controlled, double-blind trial. Ann Surg 241: 424-430, 2005.
11. Deitch EA, Winterton J, Berg R. Thermal injury promotes bacterial translocation from the gastrointestinal tract in mice with impaired T-cell-mediated immunity. Arch Surg 121: 97-101, 1986.
12. Horton JW, Maass DL, White J, Sanders B. Myocardial inflammatory responses to sepsis complicated by previous burn injury. Surg Infect 4: 363-378, 2003.
13. Horton JW, Tan J, White DJ, Maass DL, Thomas JA. Selective decontamination of the digestive tract attenuated the myocardial inflammation and dysfunction that occur with burn injury. Am J Physiol Heart Circ Physiol 287: H2241-H2251, 2004.
14. Horton JW. Bacterial translocation after burn injury: the contribution of ischemia and permeability changes. Shock 4: 286-290, 1994.
15. Kollef MH. Selective digestive decontamination should not be routinely employed. Chest 123: 464S-468S, 2003.
16. Krueger WA, Unertl KE. Selective decontamination of the digestive tract. Am J Respir Crit Care Med 8: 139-144, 2002.
17. Lingnau W, Berger J, Javorsky F, Fille M, Allerberger F, Ben H. Changing bacterial ecology during a five-year period of selective intestinal decontamination. J Hosp Infect 39: 195-206, 1998.
18. Mackie DP, van Hertum WA, Schumburg T, Kuijper EC, Knape P. Prevention of infection in burns: preliminary experience with selective decontamination of the digestive tract in patients with extensive injuries. J Trauma 32: 570-575, 1992.
19. Mackie DP, van Hertum WA, Schumburg TH, Kuijper EC, Knape P, Massaro F. Reduction in Staphylococcus aureus wound colonization using nasal mupirocin and selective decontamination of the digestive tract in extensive burns. Burns 20: S14-S17, 1994.
20. Manson WL, Klasen HJ, Sauer EW, Olieman A. Selective intestinal decontamination for prevention of wound colonization in severely burned patients: a retrospective analysis. Burns 18: 98-102, 1992.
21. Mellencamp MA, Preheim LC. Pneumococcal pneumonia in rat model of cirrhosis: effects of cirrhosis on pulmonary defense mechanisms against Streptococcus pneumoniae. J Infect Dis 163: 102-108, 1991.
22. Nathens AB, Marshall JC. Selective decontamination of the digestive tract in surgical patients: a systemic review of the evidence. Arch Surg 134: 170-176, 1999.
23. Nayci A, Atis S, Ersoz G, Polat A. Gut decontamination prevents bronchoscopy-induced bacterial translocation. An experimental study in rats. Respiration 71: 66-71, 2004.
24. Rue LW, Cioffi WG, Mason AD, McManus WF, Pruitt BA. The risk of pneumonia in thermally injured patients requiring ventilatory support. J Burn Care Rehabil 16: 262-268, 1995.
25. Sambol JT, White J, Horton JW, Deitch EA. Burn-induced impairment of cardiac contractile function is due to gut-derived factors transported in mesenteric lymph. Shock 18: 272-276, 2002.
26. Schultz MJ, de Jonge E, Kesecioglu J. Selective decontamination of the digestive tract reduces mortality in critically ill patients. Crit Care 7: 107-110, 2003.
27. Selective Decontamination of the Digestive Tract Trialists' Collaborative Group. Meta-analysis of randomised controlled trials of selective decontamination of the digestive tract. Br Med J 307: 525-532, 1993.
28. Sheeran PW, Maass DL, White DJ, Turbeville TD, Giroir BP, Horton JW. Aspiration pneumonia-induced sepsis increases cardiac dysfunction after burn trauma. J Surg Res 76: 192-199, 1998.
29. Shirani KZ, Pruitt BA Jr, Mason AD. The influence of inhalation injury and pneumonia on burn mortality. Ann Surg 295: 82-87, 1987.
30. Silvestri L, Mannucci F, van Saene HKF. Selective decontamination of the digestive tract: a live saver. J Hosp Infect 45: 185-190, 2000.
31. Stoutenbeek CP, van Saene HK, Miranda DR, Zandstra DF. The effect of selective decontamination of the digestive tract on colonization and infection rate in multiple patients. Intensive Care Med 10: 185-192, 1984.
32. White DJ, Sanders B, Horton JW. Selective decontamination of the digestive tract (SDD) attenuates post burn myocardial contractile depression associated with post burn sepsis (Abstract). Crit Care Med 32: 13, 2004.
33. White DJ, Thomas JA, Maass DL, Horton JW. Cardiac effects of burn injury complicated by aspiration pneumonia-induced sepsis. Am J Physiol Heart Circ Physiol 285: H47-H58, 2003.
34. Yao YM, Lu LR, Yu Y, Liang HP, Chen JS, Shi ZG, Zhou BT, Sheng ZY. Influence of selective decontamination of the digestive tract on cell-mediated immune function and bacteria/endotoxin translocation in thermally injured rats. J Trauma 42: 1073-1079, 1997.
35. Yao YM, Yu Y, Sheng ZY, Tian HM, Wang YP, Lu LR, Yu Y. Role of gut-derived endotoxaemia and bacterial translocation in rats after thermal injury: effects of selective decontamination of the digestive tract. Burns 21: 580-585, 1995.