A novel validated LC method for quantitation of lopinavir in bulk drug and pharmaceutical formulation in the presence of its potential impurities and degradation products

Biomedical Chromatography

Volumn 21, Issue 7, 2007, Pages 716-723

  Seshachalam, U ^a   Haribabu, B ^a   Chandrasekhar, K B ^b  

^a Matrix Laboratories Limited   (India)

^b JNTUA COLLEGE OF ENGINEERING   (India)

Author keywords

Bulk drug; Column liquid chromatography; Forced degradation; Lopinavir; Pharmaceutical formulation; Stability indicating method

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; COLUMN CHROMATOGRAPHY; DEGRADATION; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; PHOTOLYSIS; POTASSIUM COMPOUNDS; QUALITY CONTROL;

BULK DRUGS; COLUMN LIQUID CHROMATOGRAPHY; DEGRADATION PRODUCTS; DRUG FORMULATIONS; FORCED DEGRADATION; LIMITS OF QUANTITATIONS; LOPINAVIR; PHARMACEUTICAL FORMULATION; SIMPLE++; STABILITY INDICATING METHOD;

IMPURITIES;

ACETONITRILE; KELETRA; LOPINAVIR; METHANOL; POTASSIUM DIHYDROGEN PHOSPHATE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG DEGRADATION; DRUG DETERMINATION; DRUG FORMULATION; DRUG IMPURITY; DRUG STABILITY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; OXIDATION; PHOTOLYSIS; QUALITY CONTROL; SENSITIVITY AND SPECIFICITY; TEMPERATURE STRESS; ULTRAVIOLET RADIATION; VALIDATION PROCESS;

EID: 34447524016     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.810     Document Type: Article

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