Genetically glycosylated ovomucoid third domain can modulate Immunoglobulin e antibody production and cytokine response in BALB/c mice

Clinical and Experimental Allergy

Volumn 37, Issue 6, 2007, Pages 918-928

  Rupa, P ^a   Nakamura, S ^b   Mine, Y ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b SHINSHU UNIVERSITY   (Japan)

Author keywords

Food allergy; IgE; N linked glycosylation; Ovomucoid; Pichia pastoris; Th1 Th2

Indexed keywords

COMPLEMENTARY DNA; GLYCAN DERIVATIVE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN E ANTIBODY; INTERLEUKIN 4; OVOMUCOID; RECOMBINANT PROTEIN;

ALLERGIC REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME GLYCOSYLATION; FEMALE; GENE EXPRESSION; GENETIC CODE; GENOMICS; HELPER CELL; IMMUNE RESPONSE; IMMUNOMODULATION; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN SECRETION; TH1 CELL; TH2 CELL; YEAST;

ADULT; ANIMALS; ANTIBODY FORMATION; CHILD; CHILD, PRESCHOOL; DOWN-REGULATION; EGG HYPERSENSITIVITY; FEMALE; GLYCOSYLATION; HUMANS; IMMUNE TOLERANCE; IMMUNOGLOBULIN E; IMMUNOTHERAPY, ACTIVE; INTERFERON TYPE II; INTERLEUKIN-4; MICE; MICE, INBRED BALB C; OLIGOSACCHARIDES; OVOMUCIN; PICHIA; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TH1 CELLS; TH2 CELLS; TRYPSIN INHIBITORS; VACCINES;

EID: 34447513157     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2007.02720.x     Document Type: Article

References (28)

1. Kato I, Schrode J, Kohr WJ, Laskowski M Jr. Chicken ovomucoid: determination of its amino acid sequence, determination of the trypsin reactive site and preparation of all three of its domains. Biochemistry 1987 26 : 193 201.
2. Yet MG, Chin CC, Wold F. The covalent structure of individual N-linked glycopeptides from ovomucoid and asialofetuin. J Biol Chem 1988 263 : 111 7.
3. Beeley JG. The isolation of ovomucoid variants differing in carbohydrate composition. Biochem J 1971 123 : 399 405.
4. Matsuda T, Nakamura R, Nakashima I, Hasegawa Y, Shimokata K. Human IgE antibody to the carbohydrate-containing third domain of chicken ovomucoid. Biochem Biophys Res Commun 1985 129 : 505 10.
5. Besler M, Steinhart H, Paschke A. Allergenicity of hen's egg-white proteins: IgE binding of native and deglycosylated ovomucoid. Food Agric Immunol 1997 9 : 277 88.
6. Zhang JW, Mine Y. Characterization of IgE and IgG epitopes on ovomucoid using egg white allergic patient's sera. Biochem Biophys Res Commun 1998 253 : 124 7.
7. Lauer I, Foetisch K, Kolarich D et al. Hazelnut (Corylus avellana) vicilin Cor a 11: molecular characterization of a glycoprotein and its allergenic activity. Biochem J 2004 383 : 327 34.
8. Calabozo B, Barber D, Polo F. Studies on the carbohydrate moiety of Pla l 1 allergen. Identification of a major N-glycan and significance for the immunoglobulin E-binding activity. Clin Exp Allergy 2002 32 : 1628 34.
9. Okano M, Kino K, Takishita T et al. Roles of carbohydrates on Cry j 1, the major allergen of Japanese cedar pollen, in specific T-cell responses. J Allergy Clin Immunol 2001 108 : 101 8.
10. Petersen A, Schramm G, Schlaak M, Becker WM. Post-translational modifications influence IgE reactivity to the major allergen Phl p 1 of timothy grass pollen. Clin Exp Allergy 1998 28 : 315 21.
11. Nakamura S, Hata J, Kawamukai M et al. Enhanced anti-rotavirus action of human cystatin C by site-specific glycosylation in yeast. Bioconjugate Chem 2004 15 : 1289 96.
12. Cregg J, Vedvick TS, Raschke WC. Recent advances in the expression of foreign genes in Pichia pastoris. Biotechnology 1993 11 : 905 10.
13. White CE, Kempi NM, Komives EA. Expression of highly disulphide-bonded proteins in Pichia pastoris. Structure 1994 2 : 1003 5.
14. Clare JJ, Rayment FB, Ballantine SP, Sreekrishna K, Ramanos MA. High-level expression of tetanus toxin fragment C in Pichia pastoris strains containing multiple tandem integrations of the gene. Biotechnology 1991 9 : 455 60.
15. Ikegaya K, Hirose M, Ohmura T, Nokihara K. Complete determination of disulfide forms of purified recombinant human serum albumin, secreted by the yeast Pichia pastoris. Anal Chem 1997 69 : 1986 91.
16. Liu ST, Saito A, Azakami H, Kato A. Expression, purification, and characterization of an unstable lysozyme mutant in Pichia pastoris. Protein Exp Purif 2003 27 : 304 12.
17. Waterham HR, Digan ME, Koutz PJ, Lair SV, Cregg JM. Isolation of the Pichia pastoris glyceraldehyde-3-phosphate dehydrogenase gene and regulation and use of its promoter. Gene 1997 186 : 37 44.
18. Burnette WN. Western blotting: electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem 1981 112 : 195 203.
19. Kondo M, Harada H, Sunada S, Yamaguchi T. Increased selectivity in the detection of glycoproteins on nitrocellulose membranes by washing with sodium hydroxide solution. Electrophoresis 1991 12 : 685 6.
20. Dubois M, Gilles KA, Hamilton JK, Rebers PA, Smith F. Colorimetric method for determination of sugars and related substances. Anal Chem 1956 28 : 350 6.
21. Aalberse RC. Structural biology of allergens. J Allergy Clin Immunol 2000 106 : 228 38.
22. Mine Y, Zhang JW. Identification and fine mapping of IgG and IgE epitopes in ovomucoid. Biochem Biophys Res Commun 2002 292 : 1070 4.
23. Cereghino JL, Cregg JM. Heterologous protein expression in the methylotrophic yeast Pichia pastoris. FEMS Microbiol Rev 2000 24 : 45 66.
24. Schuster M, Einhauer A, Wasserbauer E et al. Protein expression in yeast; comparison of two expression strategies regarding protein maturation. J Biotechnol 2000 84 : 237 48.
25. Eggesbo M, Botten G, Halvorsen R, Magnus P. The prevalence of allergy to egg: a population-based study in young children. Allergy 2001 56 : 403 11.
26. Matsuda T, Nakashima I, Nakamura R, Shimokata K. Specificity to ovomucoid domains of human serum antibody from allergic patients: comparison with anti-ovomucoid antibody from laboratory animals. J Biochem 1986 100 : 985 8.
27. Cooke SK, Sampson HA. Allergenic properties of ovomucoid in man. J Immunol 1997 159 : 2026 32.
28. Yamashita K, Kammerling JP, Kobata A. Structural studies of the sugar chains of hen ovomucoid. Evidence indicating that they are formed mainly by the alternate biosynthetic pathway of asparagine-linked sugar chains. J Biol Chem 1982 257 : 12809 14.