Pre-operative management of a patient with hypoprothrombinemia-lupus anticoagulant syndrome

Thrombosis and Haemostasis

Volumn 98, Issue 1, 2007, Pages 248-250

  Raflores, Marion B ^a   Kaplan, Robert ^a   Spero, Joel A ^b  

^a WESTERN PENNSYLVANIA HOSPITAL   (United States)

^b ALLEGHENY GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOCAPROIC ACID; BETA2 GLYCOPROTEIN 1 ANTIBODY; CARDIOLIPIN ANTIBODY; CYCLOPHOSPHAMIDE; HEPARIN; LUPUS ANTICOAGULANT; METHYLPREDNISOLONE; PROTHROMBIN; PROTHROMBIN ANTIBODY; RITUXIMAB; STEROID;

ADULT; ANTIBODY TITER; ARTICLE; BLOOD CLOTTING DISORDER; CASE REPORT; DEEP VEIN THROMBOSIS; DRUG MEGADOSE; DRUG WITHDRAWAL; EPISTAXIS; GASTROCNEMIUS MUSCLE; HEMATURIA; HUMAN; HYPOPROTHROMBINEMIA LUPUS ANTICOAGULANT SYNDROME; INTERNAL JUGULAR VEIN; MALE; MUSCLE BLEEDING; PLASMAPHERESIS; POSTOPERATIVE CARE; POSTOPERATIVE HEMORRHAGE; PREOPERATIVE CARE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SOFT TISSUE DISEASE; SOLEUS MUSCLE; TOOTH DISEASE; TOOTH EXTRACTION;

ADULT; ANTIBODIES, MONOCLONAL; ANTIPHOSPHOLIPID SYNDROME; BLOOD LOSS, SURGICAL; HEMORRHAGE; HUMANS; HYPOPROTHROMBINEMIAS; INTRAOPERATIVE COMPLICATIONS; LUPUS COAGULATION INHIBITOR; MALE; ORAL SURGICAL PROCEDURES; PLASMA EXCHANGE; PREOPERATIVE CARE; PROTHROMBIN; STEROIDS;

EID: 34447512924     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH07-01-0014     Document Type: Article

References (19)

1. Bajaj S, Rapaport S, Fierer D. A mechanism for the hypoprothrombinemia of the acquired hypoprothrombinemia-lupus anticoagulant syndrome. Blood 1983; 61: 684.
2. Bajaj S, Rapaport S, Barclay S, et al. Acquired hypoprothrombinemia due to non-neutralizing antibodies to prothrombin: mechanisms and management. Blood 1985; 65: 1538.
3. Vinet E, Rich E, Senecal J. Thromboembolism complicating the treatment of lupus anticoagulant hypoprothrombinemia syndrome. J Rheumatol 2006; 33: 2088-2090.
4. Vivaldi P, Rossetti G, Galli M, et al. Severe bleeding due to acquired hypoprothrombinemia-lupus anticoagulant syndrome. Case report and review of literature. Haematologica 1997; 82: 345-347.
5. Colman RW. Hemostasis and Thrombosis: Basic principles in clinical practice. Philadelphia: Williams and Wilkins, 2005: p. 1106.
6. Williams S, Linardic C, Wilson O, et al. Acquired hypoprothrombinemia: effects of danazol treatment. Am J Hematol 1996; 53: 272-276.
7. Pernod G, Arvieux J, Carpentier PH, et al. Successful treatment of lupus anticoagulant-hypoprothrombinemia syndrome using intravenous immunoglobulins. Thromb Haemost 1997; 78: 969-970.
8. Simel D, St. Clair E, Adams J, et al. Correction of hypoprothrombinemia by immunosuppressive treatment of the lupus anticoagulant-hypoprothrombinemia syndrome. Am J Med 1987; 83: 563-566.
9. Holm M, Andreasen R, Ingerslev J Management of bleeding using recombinant factor VIIa in a patient suffering from bleeding tendency due to a lupus anticoagulant-hypoprothrombinemia syndrome. Thromb Haemost 1999; 82: 1776-1778.
10. Rituxan full prescribing information. Retrieved February 28, 2007, from http://www.gene.com/gene/products/information/oncology/ritaxan/ insert.jsp#indications.
11. Fakhouri F, Vernant JP, Veyradier A, et al. Efficiency of curative and prophylactic treatment with rituximab, in ADAMTS13-deficient thrombotic thrombocytopenic purpura: a study of 11 cases. Blood 2005; 106: 1932-1937.
12. Niewold T, Alpert D, Scanzello CR, et al. Rituximab treatment of thrombotic thrombocytopenic purpura in the setting of connective tissue disease. J Rheumatol 2006; 33: 1194-1196.
13. Rubenstein E, Arkfeld DG, Metyas S, et al. Rituximab treatment for resistant antiphospholipid syndrome. J Rheumatol 2006; 33: 355-357.
14. Onitilio AA, Skorupa A, Lal A, et al. Rituximab in the treatment of acquired factor VIII inhibitors. Thromb Haemost 2006; 96: 84-87.
15. Franchini M, Veneri D, Lippi G, et al. The efficacy of rituximab in the treatment of inhibitor-associated hemostatic disorders. Thromb Haemost 2006; 96: 119-125.
16. Peacock N, Levine S. Case report: The lupus anticoagulant-hypoprothrombinemia syndrome. Am J Med Sci 1994; 307: 346-349.
17. Eberhard A, Sparling C, Sudbury S, et al. Hypoprothrombinemia in childhood systemic lupus erythematosus. Semin Arthritis Rheum 1994; 24: 12-18.
18. Khamashta M. Hughes syndrome: Antiprothrombin antibodies. London: Springer-Verlag, 2006: pp. 319-328.
19. Cmolik B, Spero JA, Magovern GJ, et al. Redo cardiac surgery: late bleeding complications from topical thrombin induced factor V deficiency. 3 Thorac Cardiovasc Surg 1993; 105: 222-228.