메뉴 건너뛰기




Volumn 17, Issue 4, 2007, Pages 764-770

The role of regulatory T cells in ovarian cancer

Author keywords

Immune escape; Ovarian cancer; Regulatory T cells; Targeted therapy; Tumor immunology

Indexed keywords

ANTINEOPLASTIC AGENT; CHEMOKINE CCL22 ANTIBODY; CHEMOKINE RECEPTOR ANTAGONIST; CTLA 4 ANTIBODY; CYCLOPHOSPHAMIDE; DENILEUKIN DIFTITOX; FLUDARABINE; INTERLEUKIN 2; LYMPHOCYTE ANTIBODY; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; UNCLASSIFIED DRUG;

EID: 34447345986     PISSN: 1048891X     EISSN: 15251438     Source Type: Journal    
DOI: 10.1111/j.1525-1438.2006.00861.x     Document Type: Article
Times cited : (19)

References (94)
  • 1
    • 0347949497 scopus 로고    scopus 로고
    • Primary ovarian cancer chemotherapy: Current standards of care
    • McGuire WP 3rd., Markman M. Primary ovarian cancer chemotherapy: current standards of care. Br J Cancer 2003 89 (Suppl. 3 S3 8.
    • (2003) Br J Cancer , vol.89 , Issue.3
    • McGuire III, W.P.1    Markman, M.2
  • 2
    • 0034909802 scopus 로고    scopus 로고
    • Advances in the management of epithelial ovarian cancer
    • discussion 29-30.
    • Memarzadeh S, Berek JS. Advances in the management of epithelial ovarian cancer. J Reprod Med 2001 46: 621 9 discussion 29-30.
    • (2001) J Reprod Med , vol.46 , pp. 621-9
    • Memarzadeh, S.1    Berek, J.S.2
  • 3
    • 24344485096 scopus 로고    scopus 로고
    • Gene expression profiles associated with response to chemotherapy in epithelial ovarian cancers
    • Jazaeri AA, Awtrey CS, Chandramouli GV et al. Gene expression profiles associated with response to chemotherapy in epithelial ovarian cancers. Clin Cancer Res 2005 11: 6300 10.
    • (2005) Clin Cancer Res , vol.11 , pp. 6300-10
    • Jazaeri, A.A.1    Awtrey, C.S.2    Chandramouli, G.V.3
  • 4
    • 33645363016 scopus 로고    scopus 로고
    • Predicting the clinical behavior of ovarian cancer from gene expression profiles
    • De Smet F, Pochet NL, Engelen K et al. Predicting the clinical behavior of ovarian cancer from gene expression profiles. Int J Gynecol Cancer 2006 16 (Suppl. 1 147 51.
    • (2006) Int J Gynecol Cancer , vol.16 , Issue.1 , pp. 147-51
    • De Smet, F.1    Pochet, N.L.2    Engelen, K.3
  • 5
    • 0000161413 scopus 로고
    • The treatment of malignant tumors by repeated inoculations of erysipelas: With a report of ten original cases
    • Coley WB. The treatment of malignant tumors by repeated inoculations of erysipelas: with a report of ten original cases. Am J Med Sci 1893 105: 487 511.
    • (1893) Am J Med Sci , vol.105 , pp. 487-511
    • Coley, W.B.1
  • 6
    • 0001415346 scopus 로고
    • Über den jetzigen Stand der Karzinomforschung
    • Ehrlich P. Über den jetzigen Stand der Karzinomforschung. Ned Tijdschr Geneeskd 1909 5: 273 90.
    • (1909) Ned Tijdschr Geneeskd , vol.5 , pp. 273-90
    • Ehrlich, P.1
  • 7
    • 84965092294 scopus 로고
    • Cancer: A biological approach
    • Burnet FM. Cancer: a biological approach. Br Med J 1957 1: 779 86.
    • (1957) Br Med J , vol.1 , pp. 779-86
    • Burnet, F.M.1
  • 8
    • 0014191608 scopus 로고
    • Immunological aspects of malignant disease
    • Burnet FM. Immunological aspects of malignant disease. Lancet 1967 1: 1171 4.
    • (1967) Lancet , vol.1 , pp. 1171-4
    • Burnet, F.M.1
  • 9
    • 0014887939 scopus 로고
    • The concept of immunological surveillance
    • Burnet FM. The concept of immunological surveillance. Prog Exp Tumor Res 1970 13: 1 2.
    • (1970) Prog Exp Tumor Res , vol.13 , pp. 1-2
    • Burnet, F.M.1
  • 11
    • 0029924107 scopus 로고    scopus 로고
    • Human tumor antigens recognized by T lymphocytes
    • Boon T, van der Bruggen P. Human tumor antigens recognized by T lymphocytes. J Exp Med 1996 183: 725 9.
    • (1996) J Exp Med , vol.183 , pp. 725-9
    • Boon, T.1    Van Der Bruggen, P.2
  • 12
    • 12944325331 scopus 로고    scopus 로고
    • A listing of human tumor antigens recognized by T cells
    • update.
    • Novellino L, Castelli C, Parmiani G. A listing of human tumor antigens recognized by T cells: March 2004 update. Cancer Immunol Immunother 2005 54: 187 207.
    • (2004) Cancer Immunol Immunother , vol.54 , pp. 187-207
    • Novellino, L.1    Castelli, C.2    Parmiani, G.3
  • 13
    • 0036561909 scopus 로고    scopus 로고
    • AIDS-related malignancies
    • Boshoff C, Weiss R. AIDS-related malignancies. Nat Rev Cancer 2002 2: 373 82.
    • (2002) Nat Rev Cancer , vol.2 , pp. 373-82
    • Boshoff, C.1    Weiss, R.2
  • 14
    • 0037341533 scopus 로고    scopus 로고
    • Observing the invisible: Successful tumor immunity in humans
    • Darnell RB, Posner JB. Observing the invisible: successful tumor immunity in humans. Nat Immun 2003 4: 201.
    • (2003) Nat Immun , vol.4 , pp. 201
    • Darnell, R.B.1    Posner, J.B.2
  • 15
    • 0033972180 scopus 로고    scopus 로고
    • The HLA crossroad in tumor immunology
    • Algarra I, Cabrera T, Garrido F. The HLA crossroad in tumor immunology. Hum Immunol 2000 61: 65 73.
    • (2000) Hum Immunol , vol.61 , pp. 65-73
    • Algarra, I.1    Cabrera, T.2    Garrido, F.3
  • 16
    • 0033991158 scopus 로고    scopus 로고
    • Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance
    • Marincola FM, Jaffee EM, Hicklin DJ, Ferrone S. Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance. Adv Immunol 2000 74: 181 273.
    • (2000) Adv Immunol , vol.74 , pp. 181-273
    • Marincola, F.M.1    Jaffee, E.M.2    Hicklin, D.J.3    Ferrone, S.4
  • 17
    • 0036157853 scopus 로고    scopus 로고
    • HLA class I antigen abnormalities and immune escape by malignant cells
    • Seliger B, Cabrera T, Garrido F, Ferrone S. HLA class I antigen abnormalities and immune escape by malignant cells. Semin Cancer Biol 2002 12: 3 13.
    • (2002) Semin Cancer Biol , vol.12 , pp. 3-13
    • Seliger, B.1    Cabrera, T.2    Garrido, F.3    Ferrone, S.4
  • 19
    • 0036852191 scopus 로고    scopus 로고
    • Natural selection of tumor variants in the generation of "tumor escape" phenotypes
    • Khong HT, Restifo NP. Natural selection of tumor variants in the generation of "tumor escape" phenotypes. Nat Immun 2002 3: 999 1005.
    • (2002) Nat Immun , vol.3 , pp. 999-1005
    • Khong, H.T.1    Restifo, N.P.2
  • 21
    • 33646755569 scopus 로고    scopus 로고
    • Cancer immunosurveillance and immunoediting: The roles of immunity in suppressing tumor development and shaping tumor immunogenicity
    • Smyth MJ, Dunn GP, Schreiber RD. Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity. Adv Immunol 2006 90: 1 50.
    • (2006) Adv Immunol , vol.90 , pp. 1-50
    • Smyth, M.J.1    Dunn, G.P.2    Schreiber, R.D.3
  • 22
    • 33745258657 scopus 로고    scopus 로고
    • Tumor-driven evolution of immunosuppressive networks during malignant progression
    • Kim R, Emi M, Tanabe K, Arihiro K. Tumor-driven evolution of immunosuppressive networks during malignant progression. Cancer Res 2006 66: 5527 36.
    • (2006) Cancer Res , vol.66 , pp. 5527-36
    • Kim, R.1    Emi, M.2    Tanabe, K.3    Arihiro, K.4
  • 23
    • 27644457376 scopus 로고    scopus 로고
    • TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
    • Thomas DA, Massague J. TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell 2005 8: 369 80.
    • (2005) Cancer Cell , vol.8 , pp. 369-80
    • Thomas, D.A.1    Massague, J.2
  • 24
    • 33645853780 scopus 로고    scopus 로고
    • B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma
    • Kryczek I, Zou L, Rodriguez P et al. B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma. J Exp Med 2006 203: 871 81.
    • (2006) J Exp Med , vol.203 , pp. 871-81
    • Kryczek, I.1    Zou, L.2    Rodriguez, P.3
  • 25
    • 33745317769 scopus 로고    scopus 로고
    • Cutting edge: Induction of B7-H4 on APCs through IL-10: Novel suppressive mode for regulatory T cells
    • Kryczek I, Wei S, Zou L et al. Cutting edge: induction of B7-H4 on APCs through IL-10: novel suppressive mode for regulatory T cells. J Immunol 2006 177: 40 44.
    • (2006) J Immunol , vol.177 , pp. 40-44
    • Kryczek, I.1    Wei, S.2    Zou, L.3
  • 26
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med 2004 10: 942 9.
    • (2004) Nat Med , vol.10 , pp. 942-9
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3
  • 27
    • 28544433483 scopus 로고    scopus 로고
    • The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer
    • Wolf D, Wolf AM, Rumpold H et al. The expression of the regulatory T cell-specific forkhead box transcription factor FoxP3 is associated with poor prognosis in ovarian cancer. Clin Cancer Res 2005 11: 8326 31.
    • (2005) Clin Cancer Res , vol.11 , pp. 8326-31
    • Wolf, D.1    Wolf, A.M.2    Rumpold, H.3
  • 28
    • 0018906201 scopus 로고
    • T-cell-mediated suppression of anti-tumor immunity. An explanation for progressive growth of an immunogenic tumor
    • Berendt MJ, North RJ. T-cell-mediated suppression of anti-tumor immunity. An explanation for progressive growth of an immunogenic tumor. J Exp Med 1980 151: 69 80.
    • (1980) J Exp Med , vol.151 , pp. 69-80
    • Berendt, M.J.1    North, R.J.2
  • 29
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • Galon J, Costes A, Sanchez-Cabo F et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006 313: 1960 4.
    • (2006) Science , vol.313 , pp. 1960-4
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3
  • 30
    • 0037388367 scopus 로고    scopus 로고
    • TRANCE- and CD40 ligand-matured dendritic cells reveal MHC class I-restricted T cells specific for autologous tumor in late-stage ovarian cancer patients
    • Schlienger K, Chu CS, Woo EY et al. TRANCE- and CD40 ligand-matured dendritic cells reveal MHC class I-restricted T cells specific for autologous tumor in late-stage ovarian cancer patients. Clin Cancer Res 2003 9: 1517 27.
    • (2003) Clin Cancer Res , vol.9 , pp. 1517-27
    • Schlienger, K.1    Chu, C.S.2    Woo, E.Y.3
  • 31
    • 0037448353 scopus 로고    scopus 로고
    • Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
    • Zhang L, Conejo-Garcia JR, Katsaros D et al. Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. N Engl J Med 2003 348: 203 13.
    • (2003) N Engl J Med , vol.348 , pp. 203-13
    • Zhang, L.1    Conejo-Garcia, J.R.2    Katsaros, D.3
  • 32
    • 29444442811 scopus 로고    scopus 로고
    • Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer
    • Sato E, Olson SH, Ahn J et al. Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer. Proc Natl Acad Sci USA 2005 102: 18538 43.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 18538-43
    • Sato, E.1    Olson, S.H.2    Ahn, J.3
  • 34
    • 0030659077 scopus 로고    scopus 로고
    • Study of tumor infiltrating lymphocytes and transforming growth factor-beta as prognostic factors in breast carcinoma
    • Marrogi AJ, Munshi A, Merogi AJ et al. Study of tumor infiltrating lymphocytes and transforming growth factor-beta as prognostic factors in breast carcinoma. Int J Cancer 1997 74: 492 501.
    • (1997) Int J Cancer , vol.74 , pp. 492-501
    • Marrogi, A.J.1    Munshi, A.2    Merogi, A.J.3
  • 35
    • 0032529466 scopus 로고    scopus 로고
    • CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer
    • Naito Y, Saito K, Shiiba K et al. CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. Cancer Res 1998 58: 3491 4.
    • (1998) Cancer Res , vol.58 , pp. 3491-4
    • Naito, Y.1    Saito, K.2    Shiiba, K.3
  • 36
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003 299: 1057 61.
    • (2003) Science , vol.299 , pp. 1057-61
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 37
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immun 2003 4: 330 6.
    • (2003) Nat Immun , vol.4 , pp. 330-6
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 38
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Khattri R, Cox T, Yasayko SA, Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immun 2003 4: 337 42.
    • (2003) Nat Immun , vol.4 , pp. 337-42
    • Khattri, R.1    Cox, T.2    Yasayko, S.A.3    Ramsdell, F.4
  • 39
    • 33646168597 scopus 로고    scopus 로고
    • FOXP3: Of mice and men
    • Ziegler SF. FOXP3: of mice and men. Annu Rev Immunol 2006 24: 209 26.
    • (2006) Annu Rev Immunol , vol.24 , pp. 209-26
    • Ziegler, S.F.1
  • 40
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995 155: 1151 64.
    • (1995) J Immunol , vol.155 , pp. 1151-64
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 41
    • 0036597371 scopus 로고    scopus 로고
    • CD4+ CD25+ suppressor T cells: More questions than answers
    • Shevach EM. CD4+ CD25+ suppressor T cells: more questions than answers. Nat Rev Immunol 2002 2: 389 400.
    • (2002) Nat Rev Immunol , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 42
    • 33745817085 scopus 로고    scopus 로고
    • CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
    • Liu W, Putnam AL, Xu-Yu Z et al. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med 2006 203: 1701 11.
    • (2006) J Exp Med , vol.203 , pp. 1701-11
    • Liu, W.1    Putnam, A.L.2    Xu-Yu, Z.3
  • 43
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • Groux H, O'Garra A, Bigler M et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997 389: 737 42.
    • (1997) Nature , vol.389 , pp. 737-42
    • Groux, H.1    O'Garra, A.2    Bigler, M.3
  • 44
    • 0035186416 scopus 로고    scopus 로고
    • Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells
    • Weiner HL. Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells. Immunol Rev 2001 182: 207 14.
    • (2001) Immunol Rev , vol.182 , pp. 207-14
    • Weiner, H.L.1
  • 45
    • 17144400393 scopus 로고    scopus 로고
    • TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
    • Marie JC, Letterio JJ, Gavin M, Rudensky AY. TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J Exp Med 2005 201: 1061 7.
    • (2005) J Exp Med , vol.201 , pp. 1061-7
    • Marie, J.C.1    Letterio, J.J.2    Gavin, M.3    Rudensky, A.Y.4
  • 46
    • 0034141907 scopus 로고    scopus 로고
    • Tumors promote altered maturation and early apoptosis of monocyte-derived dendritic cells
    • Kiertscher SM, Luo J, Dubinett SM, Roth MD. Tumors promote altered maturation and early apoptosis of monocyte-derived dendritic cells. J Immunol 2000 164: 1269 76.
    • (2000) J Immunol , vol.164 , pp. 1269-76
    • Kiertscher, S.M.1    Luo, J.2    Dubinett, S.M.3    Roth, M.D.4
  • 47
    • 33747748129 scopus 로고    scopus 로고
    • Cooperative induction of a tolerogenic dendritic cell phenotype by cytokines secreted by pancreatic carcinoma cells
    • Bellone G, Carbone A, Smirne C et al. Cooperative induction of a tolerogenic dendritic cell phenotype by cytokines secreted by pancreatic carcinoma cells. J Immunol 2006 177: 3448 60.
    • (2006) J Immunol , vol.177 , pp. 3448-60
    • Bellone, G.1    Carbone, A.2    Smirne, C.3
  • 48
    • 0038325761 scopus 로고    scopus 로고
    • Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance
    • Probst HC, Lagnel J, Kollias G, van den Broek M. Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance. Immunity 2003 18: 713 20.
    • (2003) Immunity , vol.18 , pp. 713-20
    • Probst, H.C.1    Lagnel, J.2    Kollias, G.3    Van Den Broek, M.4
  • 49
    • 0036659913 scopus 로고    scopus 로고
    • Antigen-bearing immature dendritic cells induce peptide-specific CD8(+) regulatory T cells in vivo in humans
    • Dhodapkar MV, Steinman RM. Antigen-bearing immature dendritic cells induce peptide-specific CD8(+) regulatory T cells in vivo in humans. Blood 2002 100: 174 7.
    • (2002) Blood , vol.100 , pp. 174-7
    • Dhodapkar, M.V.1    Steinman, R.M.2
  • 50
    • 0037237628 scopus 로고    scopus 로고
    • Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: Dependency on antigen dose and differential toll-like receptor ligation
    • Boonstra A, Asselin-Paturel C, Gilliet M et al. Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation. J Exp Med 2003 197: 101 9.
    • (2003) J Exp Med , vol.197 , pp. 101-9
    • Boonstra, A.1    Asselin-Paturel, C.2    Gilliet, M.3
  • 52
    • 10744226674 scopus 로고    scopus 로고
    • Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes
    • Cosmi L, Liotta F, Lazzeri E et al. Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes. Blood 2003 102: 4107 14.
    • (2003) Blood , vol.102 , pp. 4107-14
    • Cosmi, L.1    Liotta, F.2    Lazzeri, E.3
  • 53
    • 0022509770 scopus 로고
    • Identification of a putative second T-cell receptor
    • Brenner MB, McLean J, Dialynas DP et al. Identification of a putative second T-cell receptor. Nature 1986 322: 145 9.
    • (1986) Nature , vol.322 , pp. 145-9
    • Brenner, M.B.1    McLean, J.2    Dialynas, D.P.3
  • 54
    • 0033168162 scopus 로고    scopus 로고
    • Depletion of IL-10- and TGF-beta-producing regulatory gamma delta T cells by administering a daunomycin-conjugated specific monoclonal antibody in early tumor lesions augments the activity of CTLs and NK cells
    • Seo N, Tokura Y, Takigawa M, Egawa K. Depletion of IL-10- and TGF-beta-producing regulatory gamma delta T cells by administering a daunomycin-conjugated specific monoclonal antibody in early tumor lesions augments the activity of CTLs and NK cells. J Immunol 1999 163: 242 9.
    • (1999) J Immunol , vol.163 , pp. 242-9
    • Seo, N.1    Tokura, Y.2    Takigawa, M.3    Egawa, K.4
  • 55
    • 0028147154 scopus 로고
    • Adoptive transfer of unresponsiveness to allogeneic skin grafts with hepatic gamma delta + T cells
    • Gorczynski RM. Adoptive transfer of unresponsiveness to allogeneic skin grafts with hepatic gamma delta + T cells. Immunology 1994 81: 27 35.
    • (1994) Immunology , vol.81 , pp. 27-35
    • Gorczynski, R.M.1
  • 56
    • 0025330735 scopus 로고
    • Gamma/delta T cell clones and natural killer cell clones mediate distinct patterns of non-major histocompatibility complex-restricted cytolysis
    • Fisch P, Malkovsky M, Braakman E et al. Gamma/delta T cell clones and natural killer cell clones mediate distinct patterns of non-major histocompatibility complex-restricted cytolysis. J Exp Med 1990 171: 1567 79.
    • (1990) J Exp Med , vol.171 , pp. 1567-79
    • Fisch, P.1    Malkovsky, M.2    Braakman, E.3
  • 57
    • 0025986933 scopus 로고
    • In vivo induction of gamma/delta T cells with highly potent and selective anti-tumor cytotoxicity
    • Ericsson PO, Hansson J, Widegren B, Dohlsten M, Sjogren HO, Hedlund G. In vivo induction of gamma/delta T cells with highly potent and selective anti-tumor cytotoxicity. Eur J Immunol 1991 21: 2797 802.
    • (1991) Eur J Immunol , vol.21 , pp. 2797-802
    • Ericsson, P.O.1    Hansson, J.2    Widegren, B.3    Dohlsten, M.4    Sjogren, H.O.5    Hedlund, G.6
  • 58
    • 26844464792 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner
    • Ghiringhelli F, Menard C, Terme M et al. CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner. J Exp Med 2005 202: 1075 85.
    • (2005) J Exp Med , vol.202 , pp. 1075-85
    • Ghiringhelli, F.1    Menard, C.2    Terme, M.3
  • 59
    • 0033571105 scopus 로고    scopus 로고
    • Induction of tumor immunity by removing CD25+CD4+ T cells: A common basis between tumor immunity and autoimmunity
    • Shimizu J, Yamazaki S, Sakaguchi S. Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J Immunol 1999 163: 5211 8.
    • (1999) J Immunol , vol.163 , pp. 5211-8
    • Shimizu, J.1    Yamazaki, S.2    Sakaguchi, S.3
  • 60
    • 12244285937 scopus 로고    scopus 로고
    • Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo
    • Chen ML, Pittet MJ, Gorelik L et al. Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Proc Natl Acad Sci USA 2005 102: 419 24.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 419-24
    • Chen, M.L.1    Pittet, M.J.2    Gorelik, L.3
  • 61
    • 0036093489 scopus 로고    scopus 로고
    • Depletion of CD4+ CD25+ regulatory cells augments the generation of specific immune T cells in tumor-draining lymph nodes
    • Tanaka H, Tanaka J, Kjaergaard J, Shu S. Depletion of CD4+ CD25+ regulatory cells augments the generation of specific immune T cells in tumor-draining lymph nodes. J Immunother 2002 25: 207 17.
    • (2002) J Immunother , vol.25 , pp. 207-17
    • Tanaka, H.1    Tanaka, J.2    Kjaergaard, J.3    Shu, S.4
  • 62
    • 0035903324 scopus 로고    scopus 로고
    • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • Sutmuller RP, van Duivenvoorde LM, van Elsas A et al. Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J Exp Med 2001 194: 823 32.
    • (2001) J Exp Med , vol.194 , pp. 823-32
    • Sutmuller, R.P.1    Van Duivenvoorde, L.M.2    Van Elsas, A.3
  • 63
    • 0035893387 scopus 로고    scopus 로고
    • Depletion of CD25(+) CD4(+) T cells and treatment with tyrosinase-related protein 2-transduced dendritic cells enhance the interferon alpha-induced, CD8(+) T-cell-dependent immune defense of B16 melanoma
    • Steitz J, Bruck J, Lenz J, Knop J, Tuting T. Depletion of CD25(+) CD4(+) T cells and treatment with tyrosinase-related protein 2-transduced dendritic cells enhance the interferon alpha-induced, CD8(+) T-cell-dependent immune defense of B16 melanoma. Cancer Res 2001 61: 8643 6.
    • (2001) Cancer Res , vol.61 , pp. 8643-6
    • Steitz, J.1    Bruck, J.2    Lenz, J.3    Knop, J.4    Tuting, T.5
  • 64
    • 25844517914 scopus 로고    scopus 로고
    • Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells
    • Ko K, Yamazaki S, Nakamura K et al. Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells. J Exp Med 2005 202: 885 91.
    • (2005) J Exp Med , vol.202 , pp. 885-91
    • Ko, K.1    Yamazaki, S.2    Nakamura, K.3
  • 65
    • 33746887327 scopus 로고    scopus 로고
    • Comparative analysis of regulatory and effector T Cells in progressively growing versus rejecting Tumors of similar origins
    • Bui JD, Uppaluri R, Hsieh C-S, Schreiber RD. Comparative analysis of regulatory and effector T Cells in progressively growing versus rejecting Tumors of similar origins. Cancer Res 2006 66: 7301 09.
    • (2006) Cancer Res , vol.66 , pp. 7301-09
    • Bui, J.D.1    Uppaluri, R.2    Hsieh, C.-S.3    Schreiber, R.D.4
  • 66
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: A renewed sense of self
    • Matzinger P. The danger model: a renewed sense of self. Science 2002 296: 301 5.
    • (2002) Science , vol.296 , pp. 301-5
    • Matzinger, P.1
  • 67
    • 0035874949 scopus 로고    scopus 로고
    • Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer
    • Woo EY, Chu CS, Goletz TJ et al. Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res 2001 61: 4766 72.
    • (2001) Cancer Res , vol.61 , pp. 4766-72
    • Woo, E.Y.1    Chu, C.S.2    Goletz, T.J.3
  • 68
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • Zou W. Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol 2006 6: 295 307.
    • (2006) Nat Rev Immunol , vol.6 , pp. 295-307
    • Zou, W.1
  • 69
    • 33748481603 scopus 로고    scopus 로고
    • An increase in CD4+CD25+FOXP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme
    • Andaloussi AE, Lesniak MS. An increase in CD4+CD25+FOXP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme. Neuro-oncol 2006 8: 234 43.
    • (2006) Neuro-oncol , vol.8 , pp. 234-43
    • Andaloussi, A.E.1    Lesniak, M.S.2
  • 70
    • 0036569127 scopus 로고    scopus 로고
    • Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation
    • Woo EY, Yeh H, Chu CS et al. Cutting edge: regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation. J Immunol 2002 168: 4272 6.
    • (2002) J Immunol , vol.168 , pp. 4272-6
    • Woo, E.Y.1    Yeh, H.2    Chu, C.S.3
  • 71
    • 18144392697 scopus 로고    scopus 로고
    • Tumour-infiltrating gamma/delta T-lymphocytes are correlated with a brief disease-free interval in advanced ovarian serous carcinoma
    • Raspollini MR, Castiglione F, Rossi Degl'Innocenti D et al. Tumour-infiltrating gamma/delta T-lymphocytes are correlated with a brief disease-free interval in advanced ovarian serous carcinoma. Ann Oncol 2005 16: 590 96.
    • (2005) Ann Oncol , vol.16 , pp. 590-96
    • Raspollini, M.R.1    Castiglione, F.2    Rossi Degl'Innocenti, D.3
  • 72
    • 33646052015 scopus 로고    scopus 로고
    • Progress in ovarian cancer research: Proceedings of the 5th Biennial Ovarian Cancer Research Symposium
    • Disis ML, Rivkin SE, Baron A et al. Progress in ovarian cancer research: proceedings of the 5th Biennial Ovarian Cancer Research Symposium. Int J Gynecol Cancer 2006 16: 463 9.
    • (2006) Int J Gynecol Cancer , vol.16 , pp. 463-9
    • Disis, M.L.1    Rivkin, S.E.2    Baron, A.3
  • 73
    • 0035180065 scopus 로고    scopus 로고
    • Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
    • Sakaguchi S, Sakaguchi N, Shimizu J et al. Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 2001 182: 18 32.
    • (2001) Immunol Rev , vol.182 , pp. 18-32
    • Sakaguchi, S.1    Sakaguchi, N.2    Shimizu, J.3
  • 74
    • 4644224624 scopus 로고    scopus 로고
    • Fatal attraction: Tumors beckon regulatory T cells
    • Shevach EM. Fatal attraction: tumors beckon regulatory T cells. Nat Med 2004 10: 900 1.
    • (2004) Nat Med , vol.10 , pp. 900-1
    • Shevach, E.M.1
  • 75
    • 0023930413 scopus 로고
    • Effect of low dose cyclophosphamide on the immune system of cancer patients: Depletion of CD4+, 2H4+ suppressor-inducer T-cells
    • Berd D, Mastrangelo MJ. Effect of low dose cyclophosphamide on the immune system of cancer patients: depletion of CD4+, 2H4+ suppressor-inducer T-cells. Cancer Res 1988 48: 1671 5.
    • (1988) Cancer Res , vol.48 , pp. 1671-5
    • Berd, D.1    Mastrangelo, M.J.2
  • 76
    • 0024598609 scopus 로고
    • Cyclophosphamide-induced immunologically mediated regression of a cyclophosphamide-resistant murine tumor: A consequence of eliminating precursor L3T4+ suppressor T-cells
    • Awwad M, North RJ. Cyclophosphamide-induced immunologically mediated regression of a cyclophosphamide-resistant murine tumor: a consequence of eliminating precursor L3T4+ suppressor T-cells. Cancer Res 1989 49: 1649 54.
    • (1989) Cancer Res , vol.49 , pp. 1649-54
    • Awwad, M.1    North, R.J.2
  • 77
    • 15944410592 scopus 로고    scopus 로고
    • Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide
    • Lutsiak ME, Semnani RT, De Pascalis R, Kashmiri SV, Schlom J, Sabzevari H. Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide. Blood 2005 105: 2862 8.
    • (2005) Blood , vol.105 , pp. 2862-8
    • Lutsiak, M.E.1    Semnani, R.T.2    De Pascalis, R.3    Kashmiri, S.V.4    Schlom, J.5    Sabzevari, H.6
  • 78
    • 24744432528 scopus 로고    scopus 로고
    • Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine
    • Beyer M, Kochanek M, Darabi K et al. Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine. Blood 2005 106: 2018 25.
    • (2005) Blood , vol.106 , pp. 2018-25
    • Beyer, M.1    Kochanek, M.2    Darabi, K.3
  • 79
    • 0037299714 scopus 로고    scopus 로고
    • Recombinant toxins for the treatment of cancer
    • Kreitman RJ. Recombinant toxins for the treatment of cancer. Curr Opin Mol Ther 2003 5: 44 51.
    • (2003) Curr Opin Mol Ther , vol.5 , pp. 44-51
    • Kreitman, R.J.1
  • 80
    • 0034280315 scopus 로고    scopus 로고
    • DAB(389)IL-2 (ONTAK): A novel fusion toxin therapy for lymphoma
    • discussion 17.
    • Foss FM. DAB(389)IL-2 (ONTAK): a novel fusion toxin therapy for lymphoma. Clin Lymphoma 2000 1: 110 6 discussion 17.
    • (2000) Clin Lymphoma , vol.1 , pp. 110-6
    • Foss, F.M.1
  • 81
    • 27444435581 scopus 로고    scopus 로고
    • Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma
    • Attia P, Maker AV, Haworth LR, Rogers-Freezer L, Rosenberg SA. Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma. J Immunother 2005 28: 582 92.
    • (2005) J Immunother , vol.28 , pp. 582-92
    • Attia, P.1    Maker, A.V.2    Haworth, L.R.3    Rogers-Freezer, L.4    Rosenberg, S.A.5
  • 82
    • 34447301899 scopus 로고    scopus 로고
    • Regulatory T cells in ovarian cancer: Biology and therapeutic potential
    • Curiel T, Barnett B, Kryczek I, Cheng P, Zou W. Regulatory T cells in ovarian cancer: biology and therapeutic potential. Cancer Immunity 2006 6: 20.
    • (2006) Cancer Immunity , vol.6 , pp. 20
    • Curiel, T.1    Barnett, B.2    Kryczek, I.3    Cheng, P.4    Zou, W.5
  • 83
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • Zou W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat Rev Cancer 2005 5: 263 74.
    • (2005) Nat Rev Cancer , vol.5 , pp. 263-74
    • Zou, W.1
  • 84
    • 33644988431 scopus 로고    scopus 로고
    • Characterization of CD4+CD25+ regulatory T cells in patients treated with high-dose interleukin-2 for metastatic melanoma or renal cell carcinoma
    • Cesana GC, DeRaffele G, Cohen S et al. Characterization of CD4+CD25+ regulatory T cells in patients treated with high-dose interleukin-2 for metastatic melanoma or renal cell carcinoma. J Clin Oncol 2006 24: 1169 77.
    • (2006) J Clin Oncol , vol.24 , pp. 1169-77
    • Cesana, G.C.1    Deraffele, G.2    Cohen, S.3
  • 85
    • 33644784733 scopus 로고    scopus 로고
    • IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients
    • Ahmadzadeh M, Rosenberg SA. IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients. Blood 2006 107: 2409 14.
    • (2006) Blood , vol.107 , pp. 2409-14
    • Ahmadzadeh, M.1    Rosenberg, S.A.2
  • 86
    • 0029947568 scopus 로고    scopus 로고
    • Enhancement of antitumor immunity by CTLA-4 blockade
    • Leach DR, Krummel MF, Allison JP. Enhancement of antitumor immunity by CTLA-4 blockade. Science 1996 271: 1734 36.
    • (1996) Science , vol.271 , pp. 1734-36
    • Leach, D.R.1    Krummel, M.F.2    Allison, J.P.3
  • 87
    • 0033592924 scopus 로고    scopus 로고
    • Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy
    • Kwon ED, Foster BA, Hurwitz AA et al. Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy. Proc Natl Acad Sci USA 1999 96: 15074 9.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 15074-9
    • Kwon, E.D.1    Foster, B.A.2    Hurwitz, A.A.3
  • 88
    • 33746924449 scopus 로고    scopus 로고
    • Combination therapy with anti-CTL antigen-4 and anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity
    • Kocak E, Lute K, Chang X et al. Combination therapy with anti-CTL antigen-4 and anti-4-1BB antibodies enhances cancer immunity and reduces autoimmunity. Cancer Res 2006 66: 7276 84.
    • (2006) Cancer Res , vol.66 , pp. 7276-84
    • Kocak, E.1    Lute, K.2    Chang, X.3
  • 89
    • 7444226411 scopus 로고    scopus 로고
    • SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo
    • Uhl M, Aulwurm S, Wischhusen J et al. SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo. Cancer Res 2004 64: 7954 61.
    • (2004) Cancer Res , vol.64 , pp. 7954-61
    • Uhl, M.1    Aulwurm, S.2    Wischhusen, J.3
  • 90
    • 23944509107 scopus 로고    scopus 로고
    • Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function
    • Peng G, Guo Z, Kiniwa Y et al. Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function. Science 2005 309: 1380 4.
    • (2005) Science , vol.309 , pp. 1380-4
    • Peng, G.1    Guo, Z.2    Kiniwa, Y.3
  • 91
    • 2442655250 scopus 로고    scopus 로고
    • Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance
    • Yang Y, Huang CT, Huang X, Pardoll DM. Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. Nat Immun 2004 5: 508 15.
    • (2004) Nat Immun , vol.5 , pp. 508-15
    • Yang, Y.1    Huang, C.T.2    Huang, X.3    Pardoll, D.M.4
  • 92
    • 1542317578 scopus 로고    scopus 로고
    • Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
    • Heil F, Hemmi H, Hochrein H et al. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 2004 303: 1526 9.
    • (2004) Science , vol.303 , pp. 1526-9
    • Heil, F.1    Hemmi, H.2    Hochrein, H.3
  • 94
    • 33744908300 scopus 로고    scopus 로고
    • Regulatory T cells and toll-like receptors in cancer therapy
    • Wang RF. Regulatory T cells and toll-like receptors in cancer therapy. Cancer Res 2006 66: 4987 90.
    • (2006) Cancer Res , vol.66 , pp. 4987-90
    • Wang, R.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.