Effects of the chemotherapeutic agents for non-Hodgkin lymphoma, cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP), on the male rat reproductive system and progeny outcome

Journal of Andrology

Volumn 28, Issue 4, 2007, Pages 578-587

  Vaisheva, Farida ^a   Delbes, Geraldine ^a   Hales, Barbara F ^a   Robaire, Bernard ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b Department of Pharmacology and Therapeutics ^*  (Canada)

Author keywords

Adverse effects; Anticancer drugs; Developmental toxicity; Male germ cell apoptosis; Spermatogenesis

Indexed keywords

ACRIDINE ORANGE; CYCLOPHOSPHAMIDE; DOXORUBICIN; PREDNISONE; VINCRISTINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL COUNT; CELL VACUOLE; CONTROLLED STUDY; DNA DETERMINATION; EPIDIDYMIS; GENOME; GERM CELL; MALE; MALE FERTILITY; MALE GENITAL SYSTEM; MULTIPLE CYCLE TREATMENT; NONHODGKIN LYMPHOMA; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGENY; RAT; REPRODUCTIVE TOXICITY; SEMINIFEROUS TUBULE; SPERMATID; SPERMATOZOON; TESTIS WEIGHT;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CYCLOPHOSPHAMIDE; DOXORUBICIN; FEMALE; HUMANS; IN SITU NICK-END LABELING; LYMPHOMA, NON-HODGKIN; MALE; NUCLEIC ACID DENATURATION; PREDNISONE; PREGNANCY; PREGNANCY OUTCOME; RATS; RATS, SPRAGUE-DAWLEY; TESTIS; TESTOSTERONE; VINCRISTINE;

EID: 34447345951     PISSN: 01963635     EISSN: None     Source Type: Journal    
DOI: 10.2164/jandrol.106.002428     Document Type: Article

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