Expression and possible functions of a novel gene SPATA12 in human testis

Journal of Andrology

Volumn 28, Issue 4, 2007, Pages 502-512

  Dan, Li ^a,b   Lifang, Yang ^c   Guangxiu, Lu ^b  

^a HUNAN UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c Central South University   (China)

Author keywords

Germ cell specific; Spermatogenesis; Stage specific

Indexed keywords

ADULT; ANIMAL CELL; ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; FLOW CYTOMETRY; GENE; GENE FUNCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LEYDIG CELL; MALE; MALE INFERTILITY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SERTOLI CELL; SPATA12 GENE; SPERMATID; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOZOON; TESTIS; TISSUE DISTRIBUTION;

BLOTTING, WESTERN; DNA PRIMERS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETIC VECTORS; HOMEODOMAIN PROTEINS; HUMANS; MALE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TESTIS;

EID: 34447337499     PISSN: 01963635     EISSN: None     Source Type: Journal    
DOI: 10.2164/jandrol.106.001560     Document Type: Article

References (28)

1. Allemand I, Anglo A, Jeantet AY. Testicular wild-type p53 expression in transgenic mice induces spermiogenesis ranging from differentiation defects to apoptosis. Oncogene. 1999;18:6521-6530.
2. Chan SW, Fowler KJ, Choo KH, Kalitsis P. Spef1, a conserved novel testis protein found in mouse sperm flagella. Gene. 2005;353: 189-199.
3. Flanagan J, Healey S, Young J, Whitehall V, Chenevix-Trench G. Analysis of the transcription regulator, CNOT7, as a candidate chromosome 8 tumor suppressor gene in colorectal cancer. Int J Cancer. 2003;106:505-509.
4. Fu J, Li L, Lu G. Relationship between microdeletion on Y chromosome and patients with idiopathic azoospermia and severe oligozoospermia in the Chinese. Chin Med J (Engl). 2002;115: 72-75.
5. Guo R, Yu Z, Guan J, Ge Y, Ma J, Li S, Wang S, Xue S, Han D. Stage-specific and tissue-specific expression characteristics of differentially expressed genes during mouse spermatogenesis. Mol Reprod Dev. 2004;67:264-272.
6. Guo Z, Hu X, Afink G, Ponten F, Wilander E, Ponten J. Comparison of chromosome 3p deletions between cervical precancers synchronous with and without invasive cancer. Int J Cancer. 2000;86: 518-523.
7. Hanke S, Bugert P, Chudek J, Kovacs G. Cloning a calcium channel alpha2delta-3 subunit gene from a putative tumor suppressor gene region at chromosome 3p21.1 in conventional renal cell carcinoma. Gene. 2001;264:69-75.
8. Hecht NB. The making of a spermatozoon: a molecular perspective. Dev Genet. 1995;16:95-103.
9. Imreh S, Klein G, Zabarovsky ER. Search for unknown tumor-antagonizing genes. Genes Chromosomes Cancer. 2003;38:307-321.
10. Kissel H, Georgescu MM, Larisch S, Manova K, Hunnicutt GR, Steller H. The Sept4 septin locus is required for sperm terminal differentiation in mice. Dev Cell. 2005;8:353-364.
11. Li D, Lu GX. Identification and expression of a novel human testis-specific gene by digital differential display. Chin Med J. 2004; 117:1791-1796.
12. Li S, Zhou W, Doglio L, Goldberg E. Transgenic mice demonstrate a testis-specific promoter for lactate dehydrogenase, LDHC. J Biol Chem. 1998;273:31191-31194.
13. Miki K, Willis WD, Brown PR, Goulding EH, Fulcher KD, Eddy EM. Targeted disruption of the Akap4 gene causes defects in sperm flagellum and motility. Dev Biol. 2002;248:331-342.
14. Modarressi MH, Cameron J, Taylor KE, Wolfe J. Identification and characterisation of a novel gene, TSGA10, expressed in testis. Gene. 2001;262:249-255.
15. Nakamura T, Yao R, Ogawa T, Suzuki T, Ito C, Tsunekawa N, Inoue K, Ajima R, Miyasaka T, Yoshida Y, Ogura A, Toshimori K, Noce T, Yamamoto T, Noda T. Oligo-astheno-teratozoospermia in mice lacking Cnot7, a regulator of retinoid X receptor beta. Nat Genet. 2004;36:528-533.
16. Roy A, Yan W, Burns KH, Matzuk MM. Tektin3 encodes an evolutionarily conserved putative testicular microtubules-related protein expressed preferentially in male germ cells. Mol Reprod Dev. 2004;67:295-302.
17. Sassone-Corsi P. Transcriptional checkpoints determining the fate of male germ cells. Cell. 1997;88:163-166.
18. Senoo M, Hoshino S, Mochida N, Matsumura Y, Habu S. Identification of a novel protein p59scr, which is expressed at specific stages of mouse spermatogenesis. Biochem Biophys Res Commun. 2002;292:992-998.
19. Siegrist S, Feral C, Chami M, Solhonne B, Mattei MG, Rajpert-De Mcyts E, Guellaen G, Bulle F. hH-RevI07, a class II tumor suppressor gene, is expressed by post-meiotic testicular germ cells and CIS cells but not by human testicular germ cell tumors. Oncogene. 2001;20:5155-5163.
20. Socher SA, Yin Y, Dewolf WC, Morgentaler A. Temperature-mediated germ cell loss in the testis is associated with altered expression of the cell-cycle regulator p53. J Urol. 1997;157: 1986-1989.
21. Takahashi T, Tanaka H, Iguchi N, Kitamura K, Chen Y, Maekawa M, Nishimura H, Ohta H, Miyagawa Y, Matsumiya K, Okuyama A, Nishimune Y. Rosbin: a novel homeobox-like protein gene expressed exclusively in round spermatids. Biol Reprod. 2004;70:1485 1492.
22. Tanaka H, Ikawa M, Tsuchida J, Nozaki M, Suzuki M, Fujiwara T, Okabe M, Nishimune Y. Cloning and characterization of the human calmegin gene encoding putative testis-specific chaperone. Gene. 1997;204:159-163.
23. Toshimori K, Yoshinaga K, Tanii I, Wakayama T, Saxena DK, Ohoka T. Protein expression and cell organelle behavior in spermatogenic cells. Kaibogaku Zasshi. 2001;76:367-379.
24. Vogt PH. Human chromosome deletions in Yq11, AZF candidate genes and male fertility: history and update. Mol Hum Reprod. 1998;4:739-744.
25. Wang L, Darling J, Zhang JS, Liu W, Qian J, Bostwick D, Hartmann L, Jenkins R, Bardenhauer W, Schutte J, Opalka B, Smith DI. Loss of expression of the DRR 1 gene at chromosomal segment 3p21.1 in renal cell carcinoma. Genes Chromosomes Cancer. 2000;27: 1-10.
26. Xue JC, Goldberg E. Identification of a novel testis-specific leucine-rich protein in humans and mice. Biol Reprod. 2000;62:1278-1284.
27. Yan W, Burns KH, Ma L, Matzuk MM. Identification of Zfp393, a germ cell-specific gene encoding a novel zinc finger protein. Mech Dev. 2002;118:233-239.
28. Zhang LP, Stroud J, Eddy CA, Walter CA, McCarrey JR. Multiple elements influence transcriptional regulation from the human testis-specific PGK2 promoter in transgenic mice. Biol Reprod. 1999;60:1329-1337.