Effects of CD40 binding on ovarian carcinoma cell growth and cytokine production in vitro

Clinical and Experimental Immunology

Volumn 149, Issue 2, 2007, Pages 372-377

  Toutirais, O ^a,b   Gervais, A ^a   Cabillic, F ^a   Le Gallo, M ^a   Coudrais, A ^a   Leveque J ^a   Catros Quemener, V ^a   Genetet, N ^a  

^a RENNES UNIVERSITY HOSPITAL   (France)

^b Inst de Med Légale   (France)

Author keywords

Cytokines interleukins; Ovarian carcinoma; Phenotype cell markers

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CANCER GROWTH; CELL CULTURE; CELL GROWTH; CELL LINE; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FLOW CYTOMETRY; GROWTH REGULATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INCIDENCE; MOUSE; NONHUMAN; OVARY CARCINOMA; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; UPREGULATION;

ANTIGENS, CD40; ANTIGENS, NEOPLASM; CD40 LIGAND; CELL DIVISION; COCULTURE TECHNIQUES; CYTOKINES; FEMALE; HUMANS; INFLAMMATION MEDIATORS; OVARIAN NEOPLASMS; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 34447318600     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2007.03426.x     Document Type: Article

References (23)

1. Quezada SA, Jarvinen LZ, Lind EF, Noelle RJ. CD40/CD154 interactions at the interface of tolerance and immunity. Annu Rev Immunol 2004 22 : 307 28.
2. Schoenberger SP, Toes RE, van der Voort EI, Offringa R, Melief CJ. T cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions. Nature 1998 393 : 480 3.
3. Thomas WD, Smith MJ, Si Z, Hersey P. Expression of the co-stimulatory molecule CD40 on melanoma cells. Int J Cancer 1996 68 : 795 801.
4. Young LS, Eliopoulos AG, Gallagher NJ, Dawson CW. CD40 and epithelial cells: across the great divide. Immunol Today 1998 19 : 502 6.
5. Sbih-Lammali F, Clausse B, Ardila-Osorio H et al. Control of apoptosis in Epstein-Barr virus-positive nasopharyngeal carcinoma cells: opposite effects of CD95 and CD40 stimulation. Cancer Res 1999 59 : 924 30.
6. Alexandroff AB, Jackson AM, Paterson T et al. Role for CD40-CD40 ligand interactions in the immune response to solid tumours. Mol Immunol 2000 37 : 515 26.
7. Byrom J, Davies Q. Cancer of the ovary. Curr Obstet Gynaecol 2003 13 : 88 94.
8. de Visser KE, Eichten A, Coussens LM. Paradoxical roles of the immune system during cancer development. Nat Rev Cancer 2006 6 : 24 37.
9. Toutirais O, Chartier P, Dubois D et al. Constitutive expression of TGF-beta1, interleukin-6 and interleukin-8 by tumor cells as a major component of immune escape in human ovarian carcinoma. Eur Cytokine Netw 2003 14 : 246 55.
10. Naylor MS, Stamp GWH, Foulkes WD, Eccles D, Balkwill FR. Tumor necrosis factor and its receptors in human ovarian cancer. J Clin Invest 1993 91 : 2194 206.
11. Garrone P, Neidhardt EM, Garcia E, Galibert L, van Kooten C, Banchereau J. Fas ligation induces apoptosis of CD40-activated human B lymphocytes. J Exp Med 1995 182 : 1265 73.
12. Cassard L, Cohen-Solal JFG, Galinha A et al. Modulation of tumor growth by inhibitory Fc{gamma} receptor expressed by human melanoma cells. J Clin Invest 2002 110 : 1549 57.
13. Armstrong A, Eck SL. EpCAM: a new therapeutic target for an old cancer antigen. Cancer Biol Ther 2003 2 : 320 6.
14. Gallagher NJ, Eliopoulos AG, Agathangelo A, Oates J, Crocker J, Young LS. CD40 activation in epithelial ovarian carcinoma cells modulates growth, apoptosis, and cytokine secretion. Mol Pathol 2002 55 : 110 20.
15. Qian Y, Zhao Z, Jiang Z, Li X. Role of NF kappa B activator Act1 in CD40-mediated signaling in epithelial cells. Proc Natl Acad Sci USA 2002 99 : 9386 91.
16. Hirano A, Longo DL, Taub DD et al. Inhibition of human breast carcinoma growth by a soluble recombinant human CD40 ligand. Blood 1999 93 : 2999 3007.
17. Jakobson E, Jonsson G, Bjorck P, Paulie S. Stimulation of CD40 in human bladder carcinoma cells inhibits anti-Fas/APO-1 (CD95)-induced apoptosis. Int J Cancer 1998 77 : 849 53.
18. Biancone L, Cantaluppi V, Boccellino M et al. Activation of CD40 favors the growth and vascularization of Kaposi's sarcoma. J Immunol 1999 163 : 6201 8.
19. Murdoch WJ, McDonnel AC. Roles of the ovarian surface epithelium in ovulation and carcinogenesis. Reproduction 2002 123 : 743 50.
20. Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet 2001 357 : 539 45.
21. Nilsson MB, Langley RR, Fidler IJ. Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine. Cancer Res 2005 65 : 10794 800.
22. Obata NH, Tamakoshi K, Shibata K, Kikkawa F, Tomoda Y. Effects of interleukin-6 on in vitro cell attachment, migration and invasion of human ovarian carcinoma. Anticancer Res 1997 17 : 337 42.
23. Herrera CA, Xu L, Bucana CD et al. Expression of metastasis-related genes in human epithelial ovarian tumors. Int J Oncol 2002 20 : 5 13.