Evaluation of neointimal hyperplasia on tranilast-coated synthetic vascular grafts: An experimental study

Journal of Investigative Surgery

Volumn 20, Issue 3, 2007, Pages 167-173

  Karakayali, Feza ^a   Haberal, Nihan ^a   Tufan, Hale ^a   Hasirci, Nesrin ^b   BaSaran, Ozgur ^a   Sevmis, Sinasi ^a   Akdur, Aydin ^a   Kiziltay, Aysel ^b   Haberal, Mehmet ^a  

^a BASKENT UNIVERSITY   (Turkey)

^b MIDDLE EAST TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Neointimal hyperplasia; Tranilast; Vascular graft

Indexed keywords

CHITOSAN; FIBROBLAST GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; POLITEF; TRANILAST; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTICLE; BLOOD VESSEL GRAFT; CAROTID ARTERY; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOPPLER FLOWMETRY; EXPERIMENTAL STUDY; GRAFT PATENCY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; MATERIAL COATING; NONHUMAN; POLITEF IMPLANT; POSTOPERATIVE PERIOD; POSTOPERATIVE THROMBOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECIPIENT; SMOOTH MUSCLE FIBER; SUTURING METHOD; TISSUE SECTION; TREATMENT OUTCOME; VASCULAR SMOOTH MUSCLE;

ANIMALS; ANTHRANILIC ACIDS; ANTI-ALLERGIC AGENTS; BLOOD VESSEL PROSTHESIS; CAROTID ARTERIES; COATED MATERIALS, BIOCOMPATIBLE; GRAFT OCCLUSION, VASCULAR; GRAFT SURVIVAL; HYPERPLASIA; POLYTETRAFLUOROETHYLENE; RATS; RATS, WISTAR; TUNICA INTIMA;

EID: 34447312826     PISSN: 08941939     EISSN: 15210553     Source Type: Journal    
DOI: 10.1080/08941930701365101     Document Type: Article

References (29)

1. Lemson, M. S., Tordoir, J. H., Daemen, M. J. and Kitslaar, P. J. (2000) Intimal hyperplasia in vascular grafts. Eur J Vasc Endovasc Surg., 19:4, pp. 336-350.
2. Goldman, S., Zadina, K. and Krasnicka, B. (1997) Predictors of graft patency 3 years after coronary artery bypass graft surgery. Department of Veterans Affairs Cooperative Study Group No. 297. J Am Coll Cardiol., 29:7, pp. 1563-1568.
3. Watase, M., Kambayashi, J. and Itoh, T. (1992) Ultrastructural analysis of pseudo-intimal hyperplasia of polytetrafluoroethylene prostheses implanted into the venous and arterial systems. Eur J Vasc Surg., 6:4, pp. 371-380.
4. Clowes, A. W. (1993) Intimal hyperplasia and graft failure. Cardiovasc Pathol, 2, pp. 179S-186S.
5. Golden, M. A., Au, Y. P. and Kirkman, T. R. (1991) Platelet-derived growth factor activity and mRNA expression in healing vascular grafts in baboons. Association in vivo of platelet-derived growth factor mRNA and protein with cellular proliferation. J Clin Invest., 87:2, pp. 406-414.
6. Clowes, A. W., Gown, A. M., Hanson, S. R. and Reidy, M. A. (1985) Mechanisms of arterial graft failure. 1. Role of cellular proliferation in early healing of PTFE prostheses. Am J Pathol., 118:1, pp. 43-54.
7. Tamai, H., Katoh, O. and Suzuki, S. (1999) Impact of tranilast on restenosis after coronary angioplasty: Tranilast restenosis following angioplasty trial (TREAT). Am Heart J., 138, pp. 968-975.
8. Miyazawa, K., Kikuchi, S., Fukuyama, J., Hamano, S. and Ujiie, A. (1995) Inhibition of PDGF- and TGF-beta 1-induced collagen synthesis, migration and proliferation by tranilast in vascular smooth muscle cells from spontaneously hypertensive rats. Atherosclerosis, 118:2, pp. 213-221.
9. Fukuyama, J., Miyazawa, K., Hamano, S. and Ujiie, A. (1996) Inhibitory effects of tranilast on proliferation, migration, and collagen synthesis of human vascular smooth muscle cells. Can J Physiol Pharmacol., 74:1, pp. 80-84.
10. Miyazawa, K., Fukuyama, J., Misawa, K., Hamano, S. and Ujiie, A. (1996) Tranilast antagonizes angiotensin II and inhibits its biological effects in vascular smooth muscle cells. Atherosclerosis., 121:2, pp. 167-173.
11. Hishikawa, K., Nakaki, T., Hirahashi, J., Marumo, T. and Saruta, T. (1996) Tranilast restores cytokine-induced nitric oxide production against platelet-derived growth factor in vascular smooth muscle cells. J Cardiovasc Pharmacol., 28:2, pp. 200-207.
12. Fukuyama, J., Ichikawa, K., Miyazawa, K., Hamano, S., Shibata, N. and Ujiie, A. (1996) Tranilast suppresses intimal hyperplasia in the balloon injury model and cuff treatment model in rabbits. Jpn J Pharmacol., 70:4, pp. 321-327.
13. Fukuyama, J., Ichikawa, K., Hamano, S. and Shibata, N. (1996) Tranilast suppresses the vascular intimal hyperplasia after balloon injury in rabbits fed on a high-cholesterol diet. Eur J Pharmacol., 318:2, pp. 327-332.
14. Ichikawa, K., Fukuyama, J. and Miyazawa, K. (1995) Suppressive effect of an anti-allergic drug, tranilast on the vascular intimal thicking by balloon catheter. Pharmacometrics., 50, pp. 539-545.
15. Kikuchi, S., Umemura, K., Kondo, K. and Nakashima, M. (1996) Tranilast suppresses intimal hyperplasia after photochemically induced endothelial injury in the rat. Eur J Pharmacol., 295:2, pp. 221-227.
16. Ishiwata, S., Choronos, N AF and Lin, G. (1998) Tranilast inhibits neointimal formation in balloon-injured and stented pig coronary arteries and decreases negative remodelling after injury. J Am Coll Cardiol., 31, p. 144.
17. Tamai, H., Katoh, K. and Yamaguchi, T. (2002) The impact of tranilast on restenosis after coronary angioplasty: The Second Tranilast Restenosis Following Angioplasty Trial (TREAT-2). Am Heart J., 143:3, pp. 506-513.
18. Jackson, M. R., Belott, T. P. and Dickason, T. (2000) The consequences of a failed femoropopliteal bypass grafting: Comparison of saphenous vein and PTFE grafts. J Vasc Surg., 32:3, pp. 498-504.
19. Nolan, K. D., Benjamin, M. E. and Murphy, T. J. (1994) Femorofemoral bypass for aortofemoral graft limb occlusion: A ten-year experience. J Vasc Surg., 19:5, pp. 851-856.
20. Lin, P. H., Chen, C., Bush, R. L., Yao, Q., Lumsden, A. B. and Hanson, S. R. (2004) Small-caliber heparin-coated ePTFE grafts reduce platelet deposition and neointimal hyperplasia in a baboon model. J Vasc Surg., 39:6, pp. 1322-1328.
21. Cagiannos, C., Abul-Khoudoud, O. R. and De Rijk, W. (2005) Rapamycin-coated expanded polytetrafluoroethylene bypass grafts exhibit decreased anastomotic neointimal hyperplasia in a porcine model. J Vasc Surg., 42:5, pp. 980-988.
22. Kosuga, K., Tamai, H. and Ueda, K. (1997) Effectiveness of tranilast on restenosis after directional coronary atherectomy. Am Heart J., 134:4, pp. 712-718.
23. Tamai, H., Katoh, O. and Suzuki, S. (1999) Impact of tranilast on restenosis after coronary angioplasty: Tranilast restenosis following angioplasty trial (TREAT). Am Heart J., 138:5, pp. 968-975.
24. Ward, M. R., Sasahara, T., Agrotis, A., Dilley, R. J., Jennings, G. L. and Bobik, A. (1998) Inhibitory effects of tranilast on expression of transforming growth factor-beta isoforms and receptors in injured arteries. Atherosclerosis, 137:2, pp. 267-275.
25. Smith, J. D., Bryant, S. R. and Couper, L. L. (1999) Soluble transforming growth factor-beta type II receptor inhibits negative remodeling, fibroblast transdifferentiation, and intimal lesion formation but not endothelial growth. Circ Res., 84:10, pp. 1212-1222.
26. Tsuji, T., Tamai, H. and Igaki, K. (2003) Biodegradable stents as a platform to drug loading. Int J Cardiovasc Intervent., 5:1, pp. 13-16.
27. Ward, M. R., Agrotis, A., Kanellakis, P., Hall, J., Jennings, G. and Bobik, A. (2002) Tranilast prevents activation of transforming growth factor-beta system, leukocyte accumulation, and neointimal growth in porcine coronary arteries after stenting. Arterioscler Thromb Vasc Biol., 22:6, pp. 940-948.
28. Shiota, N., Okunishi, H. and Takai, S. (1999) Tranilast suppresses vascular chymase expression and neointima formation in balloon-injured dog carotid artery. Circulation., 99:8, pp. 1084-1090.
29. Lafont, A. and Faxon, D. (1998) Why do animal models of post-angioplasty restenosis sometimes poorly predict the outcome of clinical trials?. Cardiovasc Res., 39:1, pp. 50-59.