Resolution of severe sinus vein thrombosis with super selective thrombolysis in a pre-adolescent with diabetic ketoacidosis and a prothrombin gene mutation

Journal of Pediatric Endocrinology and Metabolism

Volumn 20, Issue 6, 2007, Pages 725-731

  Zerah, Michele ^a   Patterson, Robert ^a   Hansen, Inger ^b   Briones, Michael ^b   Dion, Jacques ^b   Renfroe, Ben ^c  

^a Children's Clinic   (United States)

^b EMORY UNIVERSITY   (United States)

^c Children's Neurology Center   (United States)

Author keywords

Cerebral sinus vein thrombosis; Coagulopathy; Diabetes mellitus; Prothrombin gene mutation; Selective thrombolysis; Thrombophilic risk factors

Indexed keywords

ENOXAPARIN; HEPARIN; INSULIN; INSULIN ASPART; INSULIN GLARGINE; LOW MOLECULAR WEIGHT HEPARIN; NONSTEROID ANTIINFLAMMATORY AGENT; PROTHROMBIN; TISSUE PLASMINOGEN ACTIVATOR;

ABDUCENS NERVE PARALYSIS; ARTICLE; BIOCHEMISTRY; CASE REPORT; CEREBRAL SINUS THROMBOSIS; COMA; DIABETIC KETOACIDOSIS; DISEASE SEVERITY; FEMALE; FIBRINOLYTIC THERAPY; FLUID THERAPY; FOLLOW UP; GENE MUTATION; HEADACHE; HEMATOLOGY; HETEROZYGOSITY; HOSPITAL DISCHARGE; HUMAN; HYPERCOAGULABILITY; INSULIN TREATMENT; MENTAL HEALTH; PHLEBOGRAPHY; SCHOOL CHILD;

EID: 34447312709     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/JPEM.2007.20.6.725     Document Type: Article

References (19)

1. Gutierrez JA, Bagatell F, Samson MP, Theodorou AA, Berg RA. Femoral central venous catheter-associated deep venous thrombosis in children with diabetic ketoacidosis. Crit Care Med 2003; 31: 80-83.
2. Worly JM, Fortenberry JD, Hansen I, Chambliss CR, Stockwell J. Deep venous thrombosis in children with diabetic ketoacidosis and femoral central venous catheters. Pediatrics 2004; 113: e57-60.
3. Keane S, Gallagher A, Ackroyd S, McShane MA, Edge JA. Cerebral venous thrombosis during diabetic ketoacidosis. Arch Dis Child 2002; 86: 204-206.
4. Vielhaber H, Ehrenforth S, Koch HG, Scharrer I, van der Werf N, Nowak-Gottl U. Cerebral venous sinus thrombosis in infancy and childhood: role of genetic and acquired risk factors of thrombophilia. Eur J Pediatr 1998; 157: 555-560.
5. Sasiadek M, Sosnowska-Pacuszko D, Zielinska M, Turek T. Cerebral venous thrombosis as a first presentation of diabetes. Pediatr Neurol 2006; 35: 135-138.
6. Scibilia J, Finegold D, Dorman J, Becker D, Drash A. Why do children with diabetes die? Acta Endocrinol Suppl (Copenh) 1986; 279: 326-333.
7. Bonduel M, Sciuccati G, Hepner M, Torres AF, Pieroni G, Frontroth JP. Prothrombotic disorders in children with arterial ischemic stroke and sinovenous thrombosis. Arch Neurol 1999; 56: 967-971.
8. Huisman TAGM, Holzman D, Martin E, Willi UV. Cerebral venous thrombosis in childhood. Eur Radiol 2001; 11: 1760-1765.
9. Sebire G, Tabarki B, Saunders DE, Leroy I, Liesner R, Saint-Martin C, Husson B, Williams AN, Wade A, Kirkham FJ. Cerebral venous sinus thrombosis in children: risk factors, presentation, diagnosis and outcome. Brain 2005; 128: 477-489.
10. Barnes C, Newall F, Furmedge J, Mackay M, Monagle P. Cerebral sinus venous thrombosis in children. J Paediatr Child Health 2004; 40: 53-55.
11. Benedict SL, Bonkowski JL, Thompson JA, Van Orman CB, Boyer RS, Bale JF, Filloux FM. Cerebral sinovenous thrombosis in children: another reason to treat iron deficiency anemia. J Child Neurol 2004; 19: 526-531.
12. Guedes RF, Lopes AF, Santos F, Ribeiro AR, Sucesso MB. Deep cerebral venous thrombosis in an 11-year-old female. Pediatr Neurol 2006; 34: 248-251.
13. DeVeber G, Chan A, Monagle P, Marzinotto V, Armstrong D, Massicotte P, Leaker M, Andrew M. Anticoagulation therapy in pediatric patients with sinovenous thrombosis: a cohort study. Arch Neurol 1998; 55: 1533-1537.
14. DeVeber G, Andrew M, Adams C, Bjornson B, Booth F, Buckley D, Camfield C, David M, Humphreys P, Langevin P, MadDonald A, Gillet J. Cerebral sinovenous thrombosis in children. N Engl J Med 2001; 345: 417-423.
15. Horowitz M, Urdy P, Unwin H, Costens G, Greenlee R, Hise J, Kopitnik T, Botyer H, Rollins N, Samson D. Horovitz treatment of dural sinus thrombosis using selective catheterization and urokinase. Ann Neurol 1995; 38: 58-67.
16. Griesemer D, Theodorou A, Berg R, Spera T. Local fibrinolysis in cerebral venous thrombosis. Pediatr Neurol 1994; 10: 78-80.
17. Dunger DB, Sperling MA, Acerini CL, Bohn DJ, Daneman D, Danne TA, Glaser NS, Hanas R, Hintz RL, Levitsky LL, Savage MO, Tasker RC, Wolfsdorf JI. ESPE/LWPES consensus statement on diabetic ketoacidosis in children and adolescents. Arch Dis Child 2004; 89: 188-194.
18. Anhalt H, Eckert KH, Hintz RL, Neely EK. Type I diabetes mellitus, ketoacidosis and thromboembolism in an adolescent with Prader-Willi syndrome. Acta Paediatr 1996; 85: 516.
19. Frey JL, Muro GJ, McDougall CG, Dean BL, Jahnke HK. Cerebral venous thrombosis: combined intrathrombus rtPA and intravenous heparin. Stroke 1999; 30: 489-494.